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Critical Reviews™ in Oncogenesis

Publicado 4 números por año

ISSN Imprimir: 0893-9675

ISSN En Línea: 2162-6448

SJR: 0.395 SNIP: 0.322 CiteScore™:: 2.5 H-Index: 54

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MicroRNAs: Cobblestones on the Road to Cancer Metastasis

Volumen 18, Edición 4, 2013, pp. 341-355
DOI: 10.1615/CritRevOncog.2013007182
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Valentina Profumo
Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milano
Paolo Gandellini
Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori

SINOPSIS

Cancer metastasis is the product of a multistep process during which tumor cells, responding to different intrinsic and extrinsic stimuli, detach from the primary tumor mass, invade the contiguous stroma, migrate over a long distance, and colonize distant organs. Despite the well-established role of protein-coding genes behind such events, emerging evidence suggests how genetic and epigenetic alterations in microRNAs equally contribute to cancer metastasis. In this review, we retrace step-to-step all the most salient phases of the tumor dissemination process, by focusing on the role that specific microRNAs play from the time a cancer cell leaves the primary tumor until it acquires the ability to form secondary tumors at distant sites. We also provide a discussion of relevant conceptual and technological issues that need to be addressed before a microRNA-based therapy might be exploited in the clinical setting for the prevention and cure of the metastatic disease.

PALABRAS CLAVE: miRNA, metastasis, EMT, microenvironment, migration, invasion, ECM
CITADO POR

  1. Beauchemin Nicole, Arabzadeh Azadeh, Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis, Cancer and Metastasis Reviews, 32, 3-4, 2013. Crossref

  2. Wang Shaohua, Li Hanjun, Wang Jingjie, Wang Dan, RETRACTED ARTICLE: Expression of microRNA-497 and its prognostic significance in human breast cancer, Diagnostic Pathology, 8, 1, 2013. Crossref

  3. Rosenfeld Cheryl S., Animal Models of Transgenerational Epigenetic Effects, in Transgenerational Epigenetics, 2014. Crossref

  4. Chen Bo, Tang Hailin, Liu Xiaoping, Liu Peng, Yang Lu, Xie Xinhua, Ye Feng, Song Cailu, Xie Xiaoming, Wei Weidong, miR-22 as a prognostic factor targets glucose transporter protein type 1 in breast cancer, Cancer Letters, 356, 2, 2015. Crossref

  5. Ruf Christian G, Dinger Daniela, Port Matthias, Schmelz Hans-Ulrich, Wagner Walter, Matthies Cord, Müller-Myhsok Bertram, Meineke Viktor, Abend Michael, Small RNAs in the peripheral blood discriminate metastasized from non-metastasized seminoma, Molecular Cancer, 13, 1, 2014. Crossref

  6. Croset Martine, Clézardin Philippe, MicroRNA-mediated regulation of bone metastasis formation: from primary tumors to skeleton, in Bone Cancer, 2015. Crossref

  7. Maffioletti Elisabetta, Tardito Daniela, Gennarelli Massimo, Bocchio-Chiavetto Luisella, Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders, Frontiers in Cellular Neuroscience, 8, 2014. Crossref

  8. Croset Martine, Kan Casina, Clézardin Philippe, Tumour-derived miRNAs and bone metastasis, BoneKEy Reports, 4, 2015. Crossref

  9. Guan Xiangming, Cancer metastases: challenges and opportunities, Acta Pharmaceutica Sinica B, 5, 5, 2015. Crossref

  10. Xu Yanjun, Jin Juan, Liu Yiman, Huang Zhenxia, Deng Yujie, You Tao, Zhou Tianhua, Si Jianmin, Zhuo Wei, Tan Ming, Snail-Regulated MiR-375 Inhibits Migration and Invasion of Gastric Cancer Cells by Targeting JAK2, PLoS ONE, 9, 7, 2014. Crossref

  11. Han Yu-Ling, Cao Xian-E., Wang Ju-Xun, Dong Chun-Ling, Chen Hong-Tao, Correlations of microRNA-124a and microRNA-30d with clinicopathological features of breast cancer patients with type 2 diabetes mellitus, SpringerPlus, 5, 1, 2016. Crossref

  12. Ma Zhenhai, Li Yang, Xu Jingchao, Ren Qiaozhen, Yao Jihong, Tian Xiaofeng, MicroRNA-409-3p regulates cell invasion and metastasis by targeting ZEB1 in breast cancer, IUBMB Life, 68, 5, 2016. Crossref

  13. Croset Martine, Santini Daniele, Iuliani Michele, Fioramonti Marco, Zoccoli Alice, Vincenzi Bruno, Tonini Giuseppe, Pantano Francesco, MicroRNAs and Bone Metastasis: A New Challenge, Molecules, 19, 7, 2014. Crossref

  14. Xiao Xiangsheng, Chen Bo, Liu Xiaoping, Liu Peng, Zheng Guopei, Ye Feng, Tang Hailin, Xie Xiaoming, Navarro Alfons, Diallyl Disulfide Suppresses SRC/Ras/ERK Signaling-Mediated Proliferation and Metastasis in Human Breast Cancer by Up-Regulating miR-34a, PLoS ONE, 9, 11, 2014. Crossref

  15. Ruf Christian G., Port Matthias, Schmelz Hans-Ulrich, Wagner Walter, Müller Felix, Senf Sven, Matthies Cord, Müller-Myhsok Bertram, Meineke Viktor, Abend Michael, Pack Svetlana, Clinically Apparent and Occult Metastasized Seminoma: Almost Indistinguishable on the Transcriptional Level, PLoS ONE, 9, 5, 2014. Crossref

  16. CHEN ZIGUI, LI DAZHI, CHENG QUAN, MA ZHIMING, JIANG BING, PENG RENJUN, CHEN RUI, CAO YIQIANG, WAN XIN, MicroRNA-203 inhibits the proliferation and invasion of U251 glioblastoma cells by directly targeting PLD2, Molecular Medicine Reports, 9, 2, 2014. Crossref

  17. LEI PENGFEI, XIE JIE, WANG LONG, YANG XUCHENG, DAI ZIXUN, HU YIHE, microRNA-145 inhibits osteosarcoma cell proliferation and invasion by targeting ROCK1, Molecular Medicine Reports, 10, 1, 2014. Crossref

  18. Muiwo Pamchui, Pandey Priyatama, Ahmad Hafiz M., Ramachandran Suganthi S., Bhattacharya Alok, IsomiR processing during differentiation of myelogenous leukemic cell line K562 by phorbol ester PMA, Gene, 641, 2018. Crossref

  19. Zhou Jiahui, Wu Song, Chen Yuxiang, Zhao Jingfeng, Zhang Kexiang, Wang Jianlong, Chen Shijie, microRNA-143 is associated with the survival of ALDH1+CD133+ osteosarcoma cells and the chemoresistance of osteosarcoma, Experimental Biology and Medicine, 240, 7, 2015. Crossref

  20. Mishra Anupam, Mishra Subhash Chandra, Tripathi Ashoak Mani, Pandey Amita, Clinical correlation of molecular (VEGF, FGF, PDGF, c-Myc, c-Kit, Ras, p53) expression in juvenile nasopharyngeal angiofibroma, European Archives of Oto-Rhino-Laryngology, 275, 11, 2018. Crossref

  21. Wang Wei, Li Qing, Yang Tao, Li Dongsheng, Ding Feng, Sun Hongzhi, Bai Guang, Anti-cancer effect of Aquaporin 5 silencing in colorectal cancer cells in association with inhibition of Wnt/β-catenin pathway, Cytotechnology, 70, 2, 2018. Crossref

  22. Ahir Bhavesh K., Lakka Sajani S., Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive RNA-sequencing transcriptome profiling, Cellular Signalling, 53, 2019. Crossref

  23. Borchert Glen M, MicroRNA Sponge Production Using PCR-Based Concatemerization of Short DNA Oligonucleotides, MOJ Cell Science & Report, 2, 2, 2015. Crossref

  24. Profumo Valentina, Doldi Valentina, Gandellini Paolo, Zaffaroni Nadia, Targeting MicroRNAs to Withstand Cancer Metastasis, in RNA Interference, 1218, 2015. Crossref

  25. Wang Bo , Yin Mujun , Cheng Cheng , Jiang Hongpeng , Jiang Kewei , Shen Zhanlong , Ye Yingjiang , Wang Shan , Decreased expression of miR‑490‑3p in colorectal cancer predicts poor prognosis and promotes cell proliferation and invasion by targeting RAB14, International Journal of Oncology, 2018. Crossref

  26. Xia Weiqi, Hu Chunqi, Progress in Research on Tumor Metastasis Inhibitors, Current Medicinal Chemistry, 27, 34, 2020. Crossref

  27. Chen Yuan, Zhu Xue, Wang Ke, Zou Wenjun, Zhou Fanfan, Tubeimoside II inhibits TGF-β1-induced metastatic progression of human retinoblastoma cells through suppressing redoxosome-dependent EGFR activation, Chemico-Biological Interactions, 335, 2021. Crossref

  28. Zhang Hao, He Qian-Yun, Wang Guang-Chao, Tong Da-Ke, Wang Ren-Kai, Ding Wen-Bin, Li Cheng, Wei Qiang, Ding Chen, Liu Pei-Zhao, Cui Hao-Chen, Zhang Xin, Li Di, Tang Hao, Ji Fang, miR-422a inhibits osteosarcoma proliferation by targeting BCL2L2 and KRAS, Bioscience Reports, 38, 2, 2018. Crossref

  29. Gong Jianyu, Jiang Jike, Qu Jianwen, Li Ju, Chen Xin, Ruan Zhiguo, Lu Gangxu, He Yuxiao, He Xiaoshan, Sun Ruifen, Association between the rs3733846 in the flanking region of miR-143/145 and risk of cervical squamous cell carcinoma, Biomarkers in Medicine, 15, 11, 2021. Crossref

  30. Dong Liang-liang, Chen Li-ming, Wang Wei-min, Zhang Liang-ming, Decreased expression of microRNA-124 is an independent unfavorable prognostic factor for patients with breast cancer, Diagnostic Pathology, 10, 1, 2015. Crossref

  31. Yang Jue, Li Tong, Gao Chao, Lv Xiaobo, Liu Kunmei, Song Hui, Xing Yingying, Xi Tao, FOXO1 3′UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity, FEBS Letters, 588, 17, 2014. Crossref

  32. Gandellini Paolo, Doldi Valentina, Zaffaroni Nadia, microRNAs as players and signals in the metastatic cascade: Implications for the development of novel anti-metastatic therapies, Seminars in Cancer Biology, 44, 2017. Crossref

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1426 PUNTOS DE VISTA 45 DESCARGAS 32 Crossref CITAS Google
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