Publicado 6 números por año
ISSN Imprimir: 1045-4403
ISSN En Línea: 2162-6502
Indexed in
Insights on the Functional Role of Chromatin Remodelers in Osteogenic Cells
SINOPSIS
Control of eukaryotic gene expression requires interaction between sequence-specific transcription factors and their regulatory elements on the particular promoter. The dynamic alteration of chromatin structure regulates the accessibility of these elements in the genome and therefore contributes to the control of transcrip-tional activity. Here we discuss chromatin remodelling in the context of osteoblast lineage regulation. This review specifically highlights the role of the protein chromatin-related mesenchymal modulator (CReMM/CHD9), a recently identified chromatin remodeler, in osteogenic cell differentiation.
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Dahiya Rashmi, Naqvi Ahmad Abu Turab, Mohammad Taj, Alajmi Mohamed F., Rehman Md. Tabish, Hussain Afzal, Hassan Md. Imtaiyaz, Investigating the structural features of chromodomain proteins in the human genome and predictive impacts of their mutations in cancers, International Journal of Biological Macromolecules, 131, 2019. Crossref
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