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International Journal of Medicinal Mushrooms

Publicado 12 números por año

ISSN Imprimir: 1521-9437

ISSN En Línea: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Effect of Sasa veitchii Extract on Immunostimulating Activity of β-glucan (SCG) from Culinary-Medicinal Mushroom Sparassis crispa Wulf.:Fr. (Higher Basidiomycetes)

Volumen 14, Edición 6, 2012, pp. 537-547
DOI: 10.1615/IntJMedMushr.v14.i6.10
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SINOPSIS

Fungal β-glucan is a representative pathogen-associated microbial pattern (PAMP) from mushroom, yeast, and fungi, and stimulates innate as well as acquired immune systems. It is a widely used functional food to enhance immunity. Such plant extracts have been known as folk medicines and reported to show various biological activities beneficial to human health, such as anti-tumor, anti-allergic, and anti-inflammatory activities. In the present study, the cooperative effect of bamboo water-soluble methanol precipitation (BWMP), a macromolecular fraction of the hot-water extract of Sasa veitchii (Japanese folk medicine Kumazasa), and the β-glucan from the medicinal mushroom Sparassis crispa (SCG) was analyzed in vitro using DBA/2 mice. The splenocytes from male DBA/2 mice were cultured with BWMP in the presence of SCG, and the responses were assessed by measuring cytokines. BWMP suppressed IFN-γ and GM-CSF production by SCG, but not TNF-α production. To analyze the specificity of the reaction, similar experiments were conducted with BWMP in the presence of bacterial lipopolysaccharide (LPS); however, none of the cytokines were inhibited. Cytokine production of splenocytes by SCG was suggested to be largely dependent on the binding of lymphocytes with dendritic cells. Functions of BWMP were also analyzed by mixed lymphocyte reaction, and IFN-γ production was suppressed. These findings suggested that BWMP modulated the cell-to-cell contact induced by SCG and inhibited cytokine production. It is strongly suggested that the plant extracts modulate the immunostimulating effects of medicinal mushrooms. Cooperative effects of plants and mushrooms would be an important issue for functional foods.

CITADO POR
  1. Li Haiping, Liu Lizeng, Tao Yongqing, Zhao Pei, Wang Fengling, Huai Lihua, Zhi Dexian, Liu Jiangmei, Li Guoliang, Dang Chunlan, Xu Yufeng, Effects of polysaccharides from Pholiota nameko on maturation of murine bone marrow-derived dendritic cells, International Journal of Biological Macromolecules, 63, 2014. Crossref

  2. Zhang Xiaorui, Qi Chunhui, Guo Yan, Zhou Wenxia, Zhang Yongxiang, Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models, Carbohydrate Polymers, 149, 2016. Crossref

  3. Yoshioka Hiroki, Nonogaki Tsunemasa, Fukaya Shiori, Ichimaru Yoshimi, Nagatsu Akito, Yoshikawa Masae, Fujii Hirohisa, Nakao Makoto, Sasa veitchii extract protects against carbon tetrachloride-induced hepatic fibrosis in mice, Environmental Health and Preventive Medicine, 23, 1, 2018. Crossref

  4. Yoshioka Hiroki, Tominaga Sarah, Nishikawa Mai, Ichimaru Yoshimi, Maeda Tohru, Nonogaki Tsunemasa, Fujii Hirohisa, Nakao Makoto, Protective effects of Sasa veitchii extract on acute ethanol‐induced hepatotoxicity in mice , Traditional & Kampo Medicine, 7, 2, 2020. Crossref

  5. Lee Jong Seok, Kwon Duck Soo, Lee Ki Rim, Park Jun Myoung, Ha Suk-Jin, Hong Eock Kee, Mechanism of macrophage activation induced by polysaccharide from Cordyceps militaris culture broth, Carbohydrate Polymers, 120, 2015. Crossref

  6. Han Jang Mi, Lee Eun Kyeong, Gong So Youn, Sohng Jae Kyung, Kang Yue Jai, Jung Hye Jin, Sparassis crispa exerts anti-inflammatory activity via suppression of TLR-mediated NF-κB and MAPK signaling pathways in LPS-induced RAW264.7 macrophage cells, Journal of Ethnopharmacology, 231, 2019. Crossref

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