Publicado 3 números por año
ISSN Imprimir: 0892-0915
ISSN En Línea: 2375-0014
The Amygdala: Corticotropin-Releasing Factor, Steroids, and Stress
SINOPSIS
The possible function of corticotropin-releasing factor (CRF), adrenal steroids, and gonadal steroids in amygdala-mediated responses to anxiogenic or stressful stimuli is reviewed. The amygdala is part of an endogenous CRF circuitry within the brain that mediates neuroendocrine, autonomic, and behavioral changes in response to stress. The amygdala contains CRF-expressing neurons that communicate with widespread regions of the neural axis. High densities of CRF, CRF-binding protein, and CRF receptors are located in the amygdala. Direct injections of CRF into the amygdala produce anxiety-like behaviors. Release of endogenous CRF can be measured in the amygdala during stress. Potent anxiolytic actions are observed when CRF receptor antagonists are administered into the amygdala. CRF-containing neurons of the amygdala can be directly modulated by alterations in circulating glucocorticoids through glucocorticoid receptors, which are expressed in amygdaloid CRF-containing neurons. Gonadal steroid hormone receptors are found in the amygdala. They are not located in CRF immunoreactive neurons, but they are located adjacent to CRF-expressing neurons and in amygdaloid neurons that are likely to participate in central autonomic and neuroendocrine circuitry. Differences are noted between the steroid influences in the amygdala of male and female animals. Also, evidence is reviewed suggesting a modulatory role in the amygdala for gonadal and adrenal steroids in behavioral, autonomic, and neuroendocrine responses to anxiogenic stimuli.
-
Yilmazer-Hanke Deniz M., Amygdala, in The Human Nervous System, 2012. Crossref
-
Ladd Charlotte O., Huot Rebecca L., Thrivikraman K.V., Nemeroff Charles B., Meaney Michael J., Plotsky Paul M., Long-term behavioral and neuroendocrine adaptations to adverse early experience, in The Biological Basis for Mind Body Interactions, 122, 2000. Crossref
-
Dagnino-Subiabre Alexies, Pérez Miguel Ángel, Terreros Gonzalo, Cheng Michelle Y., House Patrick, Sapolsky Robert, Corticosterone treatment impairs auditory fear learning and the dendritic morphology of the rat inferior colliculus, Hearing Research, 294, 1-2, 2012. Crossref
-
Tran Viet, Hatalski Carolyn G., Yan Xiao-Xin, Baram Tallie Z., Effects of Blocking GABA Degradation on Corticotropin-Releasing Hormone Gene Expression in Selected Brain Regions, Epilepsia, 40, 9, 1999. Crossref
-
Brunson K.L., Avishai-Eliner S., Baram T.Z., Acth treatment of infantile spasms: Mechanisms of its effects in modulation of neuronal excitability, in Epilepsy, Infantile Spasms, and Development Encephalopathy, 49, 2002. Crossref
-
Quigg Mark, Chronobiology and Sleep, in Epilepsy, 2010. Crossref
-
Donner Nina C., Lowry Christopher A., Sex differences in anxiety and emotional behavior, Pflügers Archiv - European Journal of Physiology, 465, 5, 2013. Crossref
-
Gold Philip W., Chrousos George P., The Endocrinology of Melancholic and Atypical Depression: Relation to Neurocircuitry and Somatic Consequences, Proceedings of the Association of American Physicians, 111, 1, 1999. Crossref
-
Kusnecov Alexander W., Rossi-George Alba, Siegel Scott, , 1, 2001. Crossref
-
Leuner B., Shors T.J., Stress, anxiety, and dendritic spines: What are the connections?, Neuroscience, 251, 2013. Crossref
-
Pérez Miguel Ángel, Pérez-Valenzuela Catherine, Rojas-Thomas Felipe, Ahumada Juan, Fuenzalida Marco, Dagnino-Subiabre Alexies, Repeated restraint stress impairs auditory attention and GABAergic synaptic efficacy in the rat auditory cortex, Neuroscience, 246, 2013. Crossref
-
Johansson-Steensland Pia, Nyberg Fred, Chahl Loris, The anabolic androgenic steroid, nandrolone decanoate, increases the density of Fos-like immunoreactive neurons in limbic regions of guinea-pig brain, European Journal of Neuroscience, 15, 3, 2002. Crossref
-
Jochman Kimberly A., Newman Sarah M., Kalin Ned H., Bakshi Vaishali P., Corticotropin-releasing factor-1 receptors in the basolateral amygdala mediate stress-induced anorexia., Behavioral Neuroscience, 119, 6, 2005. Crossref
-
Stevenson C. W., Gratton A., Basolateral amygdala modulation of the nucleus accumbens dopamine response to stress: role of the medial prefrontal cortex, European Journal of Neuroscience, 17, 6, 2003. Crossref
-
Yilmazer-Hanke Deniz M., Faber-Zuschratter Heidi, Linke Rüdiger, Schwegler Herbert, Contribution of amygdala neurons containing peptides and calcium-binding proteins to fear-potentiated startle and exploration-related anxiety in inbred Roman high- and low-avoidance rats, European Journal of Neuroscience, 15, 7, 2002. Crossref
-
Chen Yuncai, Brunson Kristen L., M�ller Marianne B., Cariaga Wayna, Baram Tallie Z., Immunocytochemical distribution of corticotropin-releasing hormone receptor type-1 (CRF1)-like immunoreactivity in the mouse brain: Light microscopy analysis using an antibody directed against the C-terminus, The Journal of Comparative Neurology, 420, 3, 2000. Crossref
-
Brunson Kristen L, Schultz Linda, Baram Tallie Z, The in vivo proconvulsant effects of corticotropin releasing hormone in the developing rat are independent of ionotropic glutamate receptor activation, Developmental Brain Research, 111, 1, 1998. Crossref
-
FISH ERIC W., SHAHROKH DARA, BAGOT ROSE, CALDJI CHRISTIAN, BREDY TIMOTHY, SZYF MOSHE, MEANEY MICHAEL J., Epigenetic Programming of Stress Responses through Variations in Maternal Care, Annals of the New York Academy of Sciences, 1036, 1, 2006. Crossref
-
Morgan Charles A., Wang Sheila, Rasmusson Ann, Hazlett Gary, Anderson George, Charney Dennis S., Relationship Among Plasma Cortisol, Catecholamines, Neuropeptide Y, and Human Performance During Exposure to Uncontrollable Stress, Psychosomatic Medicine, 63, 3, 2001. Crossref
-
Zhang Limei, Hernández Vito S., Medina-Pizarro Mauricio, Valle-Leija Pablo, Vega-González Arturo, Morales Teresa, Maternal hyperthyroidism in rats impairs stress coping of adult offspring, Journal of Neuroscience Research, 86, 6, 2008. Crossref
-
Wang Shan-Shan, Yan Xue-Bo, Hofman Michel A., Swaab Dick F., Zhou Jiang-Ning, Increased expression level of corticotropin-releasing hormone in the amygdala and in the hypothalamus in rats exposed to chronic unpredictable mild stress, Neuroscience Bulletin, 26, 4, 2010. Crossref
-
Yilmazer-Hanke Deniz M., Morphological correlates of emotional and cognitive behaviour: insights from studies on inbred and outbred rodent strains and their crosses, Behavioural Pharmacology, 19, 5-6, 2008. Crossref
-
Day Heidi E. W., Nebel Scott, Sasse Sarah, Campeau Serge, Inhibition of the central extended amygdala by loud noise and restraint stress, European Journal of Neuroscience, 21, 2, 2005. Crossref
-
Smith Craig M., Shen Pei-Juan, Banerjee Avantika, Bonaventure Pascal, Ma Sherie, Bathgate Ross A.D., Sutton Steven W., Gundlach Andrew L., Distribution of relaxin-3 and RXFP3 within arousal, stress, affective, and cognitive circuits of mouse brain, The Journal of Comparative Neurology, 518, 19, 2010. Crossref
-
Gądek-Michalska Anna, Bugajski Jan, Interleukin-1 (IL-1) in stress-induced activation of limbic-hypothalamic-pituitary adrenal axis, Pharmacological Reports, 62, 6, 2010. Crossref
-
Krishnan Balaji, Centeno Marjorie, Pollandt Sebastian, Fu Yu, Genzer Kathy, Liu Jie, Gallagher Joel P., Shinnick-Gallagher Patricia, Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal, European Journal of Neuroscience, 31, 6, 2010. Crossref
-
Hatalski Carolyn G., Guirguis Christine, Baram Tallie Z., Corticotropin Releasing Factor mRNA Expression in the Hypothalamic Paraventricular Nucleus and the Central Nucleus of the Amygdala is Modulated by Repeated Acute Stress in the Immature Rat, Journal of Neuroendocrinology, 10, 9, 1998. Crossref
-
Mazurek B., Stöver T., Haupt H., Klapp B.F., Adli M., Gross J., Szczepek A.J., Bedeutung von Stress, HNO, 58, 2, 2010. Crossref
-
ZHANG TIE-YUAN, PARENT CARINE, WEAVER IAN, MEANEY MICHAEL J., Maternal Programming of Individual Differences in Defensive Responses in the Rat, Annals of the New York Academy of Sciences, 1032, 1, 2004. Crossref
-
Treweek Jennifer B., Jaferi Azra, Colago Eric E., Zhou Ping, Pickel Virginia M., Electron microscopic localization of corticotropin-releasing factor (CRF) and CRF receptor in rat and mouse central nucleus of the amygdala, The Journal of Comparative Neurology, 512, 3, 2009. Crossref
-
Welberg L. A. M., Seckl J. R., Prenatal Stress, Glucocorticoids and the Programming of the Brain, Journal of Neuroendocrinology, 13, 2, 2001. Crossref
-
Kapoor Amita, Matthews Stephen G., Short periods of prenatal stress affect growth, behaviour and hypothalamo-pituitary-adrenal axis activity in male guinea pig offspring, The Journal of Physiology, 566, 3, 2005. Crossref
-
Naughton Marie, Dinan Timothy G., Scott Lucinda V., Corticotropin-releasing hormone and the hypothalamic–pituitary–adrenal axis in psychiatric disease, in Clinical Neuroendocrinology, 124, 2014. Crossref
-
Kimura M, Müller-Preuss P, Lu A, Wiesner E, Flachskamm C, Wurst W, Holsboer F, Deussing J M, Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep, Molecular Psychiatry, 15, 2, 2010. Crossref
-
Maras P M, Molet J, Chen Y, Rice C, Ji S G, Solodkin A, Baram T Z, Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress, Molecular Psychiatry, 19, 7, 2014. Crossref
-
Shepard Jack D, Barron Kirk W, Myers Dean A, Corticosterone delivery to the amygdala increases corticotropin-releasing factor mRNA in the central amygdaloid nucleus and anxiety-like behavior, Brain Research, 861, 2, 2000. Crossref
-
Eggers A.E., New neural theory of migraine, Medical Hypotheses, 56, 3, 2001. Crossref
-
Gold Philip W, Drevets Wayne C, Charney Dennis S, Drevets Wayne C, New insights into the role of cortisol and the glucocorticoid receptor in severe depression, Biological Psychiatry, 52, 5, 2002. Crossref
-
Stephens Mary Ann C., McCaul Mary E., Wand Gary S., The Potential Role of Glucocorticoids and the HPA Axis in Alcohol Dependence, in Neurobiology of Alcohol Dependence, 2014. Crossref
-
Quigg Mark, Circadian rhythms: interactions with seizures and epilepsy, Epilepsy Research, 42, 1, 2000. Crossref
-
Caldji Christian, Diorio Josie, Meaney Michael J, Variations in maternal care in infancy regulate the development of stress reactivity, Biological Psychiatry, 48, 12, 2000. Crossref
-
Oberlander Joseph G, Henderson Leslie P, Corticotropin-Releasing Factor Modulation of Forebrain GABAergic Transmission has a Pivotal Role in the Expression of Anabolic Steroid-Induced Anxiety in the Female Mouse, Neuropsychopharmacology, 37, 6, 2012. Crossref
-
Crespi F., Apamin increases 5-HT cell firing in raphe dorsalis and extracellular 5-HT levels in amygdala: A concomitant in vivo study in anesthetized rats, Brain Research, 1281, 2009. Crossref
-
Croiset Gerda, Nijsen Marjoleen J.M.A, Kamphuis Patrick J.G.H, Role of corticotropin-releasing factor, vasopressin and the autonomic nervous system in learning and memory, European Journal of Pharmacology, 405, 1-3, 2000. Crossref
-
Sajdyk Tammy J., Shekhar Anantha, Gehlert Donald R., Interactions between NPY and CRF in the amygdala to regulate emotionality, Neuropeptides, 38, 4, 2004. Crossref
-
Basso Alexandre Salgado, Azevedo Costa Pinto Frederico, Russo Momtchilo, Giorgetti Britto Luiz Roberto, de Sá-Rocha Luiz Carlos, Palermo Neto João, Neural correlates of IgE-mediated food allergy, Journal of Neuroimmunology, 140, 1-2, 2003. Crossref
-
Mitra Rupshi, Sapolsky Robert M, Gene therapy in rodent amygdala against fear disorders, Expert Opinion on Biological Therapy, 10, 9, 2010. Crossref
-
Perkeybile Allison M., Bales Karen L., Early rearing experience is associated with vasopressin immunoreactivity but not reactivity to an acute non-social stressor in the prairie vole, Physiology & Behavior, 147, 2015. Crossref
-
Zhou Yan, Spangler Rudolph, Ho Ann, Jeanne Kreek Mary, Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic ‘binge’ cocaine, Molecular Brain Research, 114, 1, 2003. Crossref
-
Thielen Shelley K., Shekhar Anantha, Amygdala priming results in conditioned place avoidance, Pharmacology Biochemistry and Behavior, 71, 3, 2002. Crossref
-
Greenwood-Van Meerveld Beverley, Gibson Matthew, Gunter Wesley, Shepard Jack, Foreman Robert, Myers Dean, Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats, Brain Research, 893, 1-2, 2001. Crossref
-
Simms Jeffrey A, Haass-Koffler Carolina L, Bito-Onon Jade, Li Rui, Bartlett Selena E, Mifepristone in the Central Nucleus of the Amygdala Reduces Yohimbine Stress-Induced Reinstatement of Ethanol-Seeking, Neuropsychopharmacology, 37, 4, 2012. Crossref
-
Stevenson C.W., Sullivan R.M., Gratton A., Effects of basolateral amygdala dopamine depletion on the nucleus accumbens and medial prefrontal cortical dopamine responses to stress, Neuroscience, 116, 1, 2003. Crossref
-
Wang Bin, Luo Fei, Ge Xue-Cai, Fu Ai-Hua, Han Ji-Sheng, Effects of lesions of various brain areas on drug priming or footshock-induced reactivation of extinguished conditioned place preference, Brain Research, 950, 1-2, 2002. Crossref
-
Giaccio Richard G., The dual origin hypothesis: An evolutionary brain-behavior framework for analyzing psychiatric disorders, Neuroscience & Biobehavioral Reviews, 30, 4, 2006. Crossref
-
Smialowska M., Bajkowska M., Heilig M., Obuchowicz E., Turchan J., Maj M., Przewlocki R., Pharmacological studies on the monoaminergic influence on the synthesis and expression of neuropeptide Y and corticotropin releasing factor in rat brain amygdala, Neuropeptides, 35, 2, 2001. Crossref
-
Day Heidi E.W., Kryskow Elisa M., Nyhuis Tara J., Herlihy Lauren, Campeau Serge, Conditioned fear inhibits c-fos mRNA expression in the central extended amygdala, Brain Research, 1229, 2008. Crossref
-
Nelson P.Austin, Sutcliffe J.Gregor, Thomas Elizabeth A, A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain, Gene Expression Patterns, 1, 2, 2002. Crossref
-
Nozu Tsukasa, Okumura Toshikatsu, Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome, Journal of Gastroenterology, 50, 8, 2015. Crossref
-
Pecoraro Norman, Dallman Mary F., Warne James P., Ginsberg Abigail B., Laugero Kevin D., la Fleur Susanne E., Houshyar Hani, Gomez Francisca, Bhargava Aditi, Akana Susan F., From Malthus to motive: How the HPA axis engineers the phenotype, yoking needs to wants, Progress in Neurobiology, 79, 5-6, 2006. Crossref
-
Zhang Qian, Li Houkai, Guo Feifan, Amygdala, an important regulator for food intake, Frontiers in Biology, 6, 1, 2011. Crossref
-
Steckler Thomas, Holsboer Florian, Corticotropin-releasing hormone receptor subtypes and emotion, Biological Psychiatry, 46, 11, 1999. Crossref
-
Menard Janet, Treit Dallas, Effects of centrally administered anxiolytic compounds in animal models of anxiety, Neuroscience & Biobehavioral Reviews, 23, 4, 1999. Crossref
-
Maeng Lisa Y., Milad Mohammed R., Sex differences in anxiety disorders: Interactions between fear, stress, and gonadal hormones, Hormones and Behavior, 76, 2015. Crossref
-
Juster Robert-Paul, Bizik Gustav, Picard Martin, Arsenault-Lapierre Genevieve, Sindi Shireen, Trepanier Lyane, Marin Marie-France, Wan Nathalie, Sekerovic Zoran, Lord Catherine, Fiocco Alexandra J., Plusquellec Pierrich, McEwen Bruce S., Lupien Sonia J., A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development, Development and Psychopathology, 23, 3, 2011. Crossref
-
Szyf Moshe, Weaver Ian C.G., Champagne Francis A., Diorio Josie, Meaney Michael J., Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat, Frontiers in Neuroendocrinology, 26, 3-4, 2005. Crossref
-
Kramer Kristin M., Simmons Jennifer L., Freeman David A., Photoperiod alters central distribution of estrogen receptor α in brain regions that regulate aggression, Hormones and Behavior, 53, 2, 2008. Crossref
-
Goodman Aviel, Neurobiology of addiction, Biochemical Pharmacology, 75, 1, 2008. Crossref
-
Wang Lixin, Martı́nez Vicente, Vale Wylie, Taché Yvette, Fos induction in selective hypothalamic neuroendocrine and medullary nuclei by intravenous injection of urocortin and corticotropin-releasing factor in rats, Brain Research, 855, 1, 2000. Crossref
-
Sterrenburg Linda, Borch Alexandra, Peeters Bernard W.M.M., Pintér Ottó, Zelena Dóra, Roubos Eric W., Kozicz Tamás, Acute ether stress differentially affects corticotropin-releasing factor and urocortin 1 in the Brattleboro rat, Brain Research, 1398, 2011. Crossref
-
Vazquez Delia M., Bailey Charles, Dent Gersham W., Okimoto Darren K., Steffek Amy, López Juan F., Levine Seymour, Brain corticotropin-releasing hormone (CRH) circuits in the developing rat: Effect of maternal deprivation, Brain Research, 1121, 1, 2006. Crossref
-
Baram Tallie Z., Hatalski Carolyn G., Neuropeptide-mediated excitability: a key triggering mechanism for seizure generation in the developing brain, Trends in Neurosciences, 21, 11, 1998. Crossref
-
Valentino R.J., Commons K.G., Peptides that fine-tune the serotonin system, Neuropeptides, 39, 1, 2005. Crossref
-
Clarke Toni-Kim, Schumann Gunter, Gene–environment interactions resulting in risk alcohol drinking behaviour are mediated by CRF and CRF1, Pharmacology Biochemistry and Behavior, 93, 3, 2009. Crossref
-
McCormick Cheryl M, Rioux Tina, Fisher Ronaldo, Lang Kate, MacLaury Kyle, Teillon Sarah M, Effects of neonatal corticosterone treatment on maze performance and HPA axis in juvenile rats, Physiology & Behavior, 74, 3, 2001. Crossref
-
Francis Darlene D, Caldji Christian, Champagne Frances, Plotsky Paul M, Meaney Michael J, The role of corticotropin-releasing factor–norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress, Biological Psychiatry, 46, 9, 1999. Crossref
-
Brunson Kristen L, Eghbal-Ahmadi Mariam, Baram Tallie Z, How do the many etiologies of West syndrome lead to excitability and seizures? The corticotropin releasing hormone excess hypothesis, Brain and Development, 23, 7, 2001. Crossref
-
Korosi Aniko, Baram Tallie Z., The central corticotropin releasing factor system during development and adulthood, European Journal of Pharmacology, 583, 2-3, 2008. Crossref
-
Asan E., Yilmazer-Hanke D.M., Eliava M., Hantsch M., Lesch K.-P., Schmitt A., The Corticotropin-Releasing Factor (CRF)-system and monoaminergic afferents in the central amygdala: Investigations in different mouse strains and comparison with the rat, Neuroscience, 131, 4, 2005. Crossref
-
Loman Michelle M., Gunnar Megan R., Early experience and the development of stress reactivity and regulation in children, Neuroscience & Biobehavioral Reviews, 34, 6, 2010. Crossref
-
Al-Mana D., Ceranic B., Djahanbakhch O., Luxon L.M., Hormones and the auditory system: A review of physiology and pathophysiology, Neuroscience, 153, 4, 2008. Crossref
-
Francis Darlene D, Meaney Michael J, Maternal care and the development of stress responses, Current Opinion in Neurobiology, 9, 1, 1999. Crossref
-
Krysiak R., Obuchowicz E., Herman Z.S., Conditioned fear-induced changes in neuropeptide Y-like immunoreactivity in rats: the effect of diazepam and buspirone, Neuropeptides, 34, 3-4, 2000. Crossref
-
Benes Francine M., The Development of the Prefrontal Cortex: The Maturation of Neurotransmitter Systems and Their Interactions, in Developmental Psychopathology, 2015. Crossref
-
Fries Eva, Dettenborn Lucia, Kirschbaum Clemens, The cortisol awakening response (CAR): Facts and future directions, International Journal of Psychophysiology, 72, 1, 2009. Crossref
-
Johnson Anthony C., Greenwood-Van Meerveld Beverley, Knockdown of steroid receptors in the central nucleus of the amygdala induces heightened pain behaviors in the rat, Neuropharmacology, 93, 2015. Crossref
-
Cook Christian J., Stress induces CRF release in the paraventricular nucleus, and both CRF and GABA release in the amygdala, Physiology & Behavior, 82, 4, 2004. Crossref
-
Marin Marie-France, Pilgrim Kamala, Lupien Sonia J., Modulatory effects of stress on reactivated emotional memories, Psychoneuroendocrinology, 35, 9, 2010. Crossref
-
Bangasser Debra A., Shors Tracey J., Critical brain circuits at the intersection between stress and learning, Neuroscience & Biobehavioral Reviews, 34, 8, 2010. Crossref
-
Yilmazer-Hanke D.M, Hantsch M, Hanke J, Schulz C, Faber-Zuschratter H, Schwegler H, Neonatal thyroxine treatment: changes in the number of corticotropin-releasing-factor (CRF) and neuropeptide Y (NPY) containing neurons and density of tyrosine hydroxylase positive fibers (TH) in the amygdala correlate with anxiety-related behavior of wistar rats, Neuroscience, 124, 2, 2004. Crossref
-
Cameron Nicole M., Champagne Frances A., Parent Carine, Fish Eric W., Ozaki-Kuroda Kumi, Meaney Michael J., The programming of individual differences in defensive responses and reproductive strategies in the rat through variations in maternal care, Neuroscience & Biobehavioral Reviews, 29, 4-5, 2005. Crossref
-
Király András, Szabó Nikoletta, Tóth Eszter, Csete Gergő, Faragó Péter, Kocsis Krisztián, Must Anita, Vécsei László, Kincses Zsigmond Tamás, Male brain ages faster: the age and gender dependence of subcortical volumes, Brain Imaging and Behavior, 10, 3, 2016. Crossref
-
Hatalski C.G, Brunson K.L, Tantayanubutr B, Chen Y, Baram T.Z, Neuronal activity and stress differentially regulate hippocampal and hypothalamic corticotropin-releasing hormone expression in the immature rat, Neuroscience, 101, 3, 2000. Crossref
-
Ragu Varman Durairaj, Marimuthu Ganapathy, Emmanuvel Rajan Koilmani, Environmental enrichment exerts anxiolytic effects in the Indian field mouse (Mus booduga), Applied Animal Behaviour Science, 136, 2-4, 2012. Crossref
-
Alfvén Gösta, Plasma Oxytocin in Children with Recurrent Abdominal Pain, Journal of Pediatric Gastroenterology and Nutrition, 38, 5, 2004. Crossref
-
David Daniel, Matu Silviu, Mogoaşe Cristina, Voinescu Bogdan, Integrating Cognitive Processing, Brain Activity, Molecules and Genes to Advance Evidence-Based Psychological Treatment for Depression and Anxiety: From Cognitive Neurogenetics to CBT-Based Neurogenetics, Journal of Rational-Emotive & Cognitive-Behavior Therapy, 34, 3, 2016. Crossref
-
Reyes Beverly A. S., Kravets J. L., Connelly K. L., Unterwald E. M., Van Bockstaele E. J., Localization of the delta opioid receptor and corticotropin-releasing factor in the amygdalar complex: role in anxiety, Brain Structure and Function, 222, 2, 2017. Crossref
-
Lowry Christopher A., Johnson Philip L., Hay-Schmidt Anders, Mikkelsen Jens, Shekhar Anantha, Modulation of anxiety circuits by serotonergic systems, Stress, 8, 4, 2005. Crossref
-
Shekhar Anantha, Truitt William, Rainnie Donald, Sajdyk Tammy, Role of stress, corticotrophin releasing factor (CRF) and amygdala plasticity in chronic anxiety, Stress, 8, 4, 2005. Crossref
-
Wisłowska-Stanek Aleksandra, Lehner Małgorzata, Skórzewska Anna, Krząścik Paweł, Płaźnik Adam, Behavioral effects and CRF expression in brain structures of high- and low-anxiety rats after chronic restraint stress, Behavioural Brain Research, 310, 2016. Crossref
-
Murck H, Nickel T, Künzel H, Antonijevic I A, Schill J, Zobel A, Steiger A, Sonntag A, Holsboer F, State Markers of Depression in Sleep EEG: Dependency on Drug and Gender in Patients Treated with Tianeptine or Paroxetine, Neuropsychopharmacology, 28, 2, 2003. Crossref
-
Chun Lauren E., Woodruff Elizabeth R., Morton Sarah, Hinds Laura R., Spencer Robert L., Variations in Phase and Amplitude of Rhythmic Clock Gene Expression across Prefrontal Cortex, Hippocampus, Amygdala, and Hypothalamic Paraventricular and Suprachiasmatic Nuclei of Male and Female Rats, Journal of Biological Rhythms, 30, 5, 2015. Crossref
-
Hall Shannon, Deurveilher Samüel, Ko Kristin Robin, Burns Joan, Semba Kazue, Region-specific increases in FosB/ΔFosB immunoreactivity in the rat brain in response to chronic sleep restriction, Behavioural Brain Research, 322, 2017. Crossref
-
Juster Robert-Paul, Vencill Jennifer A., Johnson Philip Jai, Impact of Stress and Strain on Current LGBT Health Disparities, in Trauma, Resilience, and Health Promotion in LGBT Patients, 2017. Crossref
-
Qin Chao, Meerveld Beverley Greenwood-Van, Foreman Robert D., Visceromotor and Spinal Neuronal Responses to Colorectal Distension in Rats With Aldosterone Onto the Amygdala, Journal of Neurophysiology, 90, 1, 2003. Crossref
-
Ma Xin-Ming, Johnson Richard C., Mains Richard E., Eipper Betty A., Expression of Kalirin, a neuronal GDP/GTP exchange factor of the Trio family, in the central nervous system of the adult rat, The Journal of Comparative Neurology, 429, 3, 2001. Crossref
-
Müller Marianne B, Zimmermann Stephan, Sillaber Inge, Hagemeyer Thomas P, Deussing Jan M, Timpl Peter, Kormann Michael S D, Droste Susanne K, Kühn Ralf, Reul Johannes M H M, Holsboer Florian, Wurst Wolfgang, Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress, Nature Neuroscience, 6, 10, 2003. Crossref
-
Thorsell Annika, Brain neuropeptide Y and corticotropin-releasing hormone in mediating stress and anxiety, Experimental Biology and Medicine, 235, 10, 2010. Crossref
-
Vázquez Delia M, Eskandari Ramin, Phelka Andrew, López Juan F, Impact of Maternal Deprivation on Brain Corticotropin-Releasing Hormone Circuits: Prevention of CRH Receptor-2 mRNA Changes by Desipramine Treatment, Neuropsychopharmacology, 28, 5, 2003. Crossref
-
Bolton Jessica L., Molet Jenny, Regev Limor, Chen Yuncai, Rismanchi Neggy, Haddad Elizabeth, Yang Derek Z., Obenaus Andre, Baram Tallie Z., Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene, Biological Psychiatry, 83, 2, 2018. Crossref
-
Palacios-García Ismael, Lara-Vásquez Ariel, Montiel Juan F., Díaz-Véliz Gabriela F., Sepúlveda Hugo, Utreras Elías, Montecino Martín, González-Billault Christian, Aboitiz Francisco, CHAVIS Pascale, Prenatal Stress Down-Regulates Reelin Expression by Methylation of Its Promoter and Induces Adult Behavioral Impairments in Rats, PLOS ONE, 10, 2, 2015. Crossref
-
Vathy Ilona, Prenatal opiate exposure: long-term CNS consequences in the stress system of the offspring, Psychoneuroendocrinology, 27, 1-2, 2002. Crossref
-
Koprdova Romana, Osacka Jana, Mach Mojmir, Kiss Alexander, Acute Impact of Selected Pyridoindole Derivatives on Fos Expression in Different Structures of the Rat Brain, Cellular and Molecular Neurobiology, 38, 1, 2018. Crossref
-
Dallman Mary F., Viau Victor G., Bhatnagar Seema, Gomez Francisca, Laugero Kevin, Bell M.E., Corticotropin-Releasing Factor, Corticosteroids, Stress, and Sugar, in Hormones, Brain and Behavior, 2002. Crossref
-
Wolak Michael L., deJoseph M. Regina, Cator Allison D., Mokashi Ashwini S., Brownfield Mark S., Urban Janice H., Comparative distribution of neuropeptide Y Y1 and Y5 receptors in the rat brain by using immunohistochemistry, The Journal of Comparative Neurology, 464, 3, 2003. Crossref
-
Zhang Xin, Ge Tong tong, Yin Guanghao, Cui Ranji, Zhao Guoqing, Yang Wei, Stress-Induced Functional Alterations in Amygdala: Implications for Neuropsychiatric Diseases, Frontiers in Neuroscience, 12, 2018. Crossref
-
Walker Claire-Dominique, Welberg Leonie A.M., Plotsky Paul M., Glucocorticoids, Stress, and Development, in Hormones, Brain and Behavior, 2002. Crossref
-
Seedat S., Stein M.B., Kennedy C.M., Hauger R.L., Plasma cortisol and neuropeptide Y in female victims of intimate partner violence, Psychoneuroendocrinology, 28, 6, 2003. Crossref
-
Weisinger Harrison, Begg Denovan, Sinclair Andrew, Jois Markandeya, Stahl Lauren, Weisinger Richard, The Role of Omega-3 Polyunsaturated Fatty Acids in Food Intake and Energy Homeostasis, in Fatty Acids in Foods and their Health Implications,Third Edition, 20073230, 2007. Crossref
-
Avishai-Eliner Sarit, Eghbal-Ahmadi Mariam, Tabachnik Elvan, Brunson Kristen L., Baram Tallie Z., Down-Regulation of Hypothalamic Corticotropin-Releasing Hormone Messenger Ribonucleic Acid (mRNA) Precedes Early-Life Experience-Induced Changes in Hippocampal Glucocorticoid Receptor mRNA**This work was supported by NIH Grants NS-28912 and NS-39307., Endocrinology, 142, 1, 2001. Crossref
-
Juster Robert-Paul, Sex × Gender and Sexual Orientation in Relation to Stress Hormones and Allostatic Load, Gender and the Genome, 3, 2019. Crossref
-
Ishai Amorina, Osborne Michael T, Tung Brian, Wang Ying, Hammad Basma, Patrich Tomas, Oberfeld Blake, Fayad Zahi A, Giles Jon T, Lo Janet, Shin Lisa M, Grinspoon Steven K, Koenen Karestan C, Pitman Roger K, Tawakol Ahmed, Amygdalar Metabolic Activity Independently Associates With Progression of Visceral Adiposity, The Journal of Clinical Endocrinology & Metabolism, 104, 4, 2019. Crossref
-
Ladd Charlotte O., Thrivikraman K.V., Huot Rebecca L., Plotsky Paul M., Differential neuroendocrine responses to chronic variable stress in adult Long Evans rats exposed to handling-maternal separation as neonates, Psychoneuroendocrinology, 30, 6, 2005. Crossref
-
Acosta Henriette, Tuulari Jetro J., Scheinin Noora M., Hashempour Niloofar, Rajasilta Olli, Lavonius Tuomas I., Pelto Juho, Saunavaara Virva, Parkkola Riitta, Lähdesmäki Tuire, Karlsson Linnea, Karlsson Hasse, Maternal Pregnancy-Related Anxiety Is Associated With Sexually Dimorphic Alterations in Amygdala Volume in 4-Year-Old Children, Frontiers in Behavioral Neuroscience, 13, 2019. Crossref
-
Dar Tawseef, Radfar Azar, Abohashem Shady, Pitman Roger K., Tawakol Ahmed, Osborne Michael T., Psychosocial Stress and Cardiovascular Disease, Current Treatment Options in Cardiovascular Medicine, 21, 5, 2019. Crossref
-
Gully Danielle, Geslin Michel, Serva Laurence, Fontaine Evelyne, Roger Pierre, Lair Christine, Darre Valerie, Marcy Claudine, Rouby Pierre-Eric, Simiand Jacques, Guitard Josette, Gout Georgette, Steinberg Regis, Rodier Daniel, Griebel Guy, Soubrie Philippe, Pascal Marc, Pruss Rebecca, Scatton Bernard, Maffrand Jean-Pierre, Le Fur Gerard, 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine Hydrochloride (SSR125543A): A Potent and Selective Corticotrophin-Releasing Factor1Receptor Antagonist. I. Biochemical and Pharmacological Characterization, Journal of Pharmacology and Experimental Therapeutics, 301, 1, 2002. Crossref
-
Arakawa Hiroyuki, Arakawa Keiko, Blandino Peter, Deak Terrence, The role of neuroinflammation in the release of aversive odor cues from footshock-stressed rats: Implications for the neural mechanism of alarm pheromone, Psychoneuroendocrinology, 36, 4, 2011. Crossref
-
Ito Masao, Miyata Mariko, Corticotropin-Releasing Factor (CRF) and its Role in the Central Nervous System, in Regulatory Peptides and Cognate Receptors, 26, 1999. Crossref
-
Juster Robert-Paul, Russell Jennifer J., Almeida Daniel, Picard Martin, Allostatic load and comorbidities: A mitochondrial, epigenetic, and evolutionary perspective, Development and Psychopathology, 28, 4pt1, 2016. Crossref
-
Zhang Tie-Yuan, Bagot Rose, Parent Carine, Nesbitt Cathy, Bredy Timothy W., Caldji Christian, Fish Eric, Anisman Hymie, Szyf Moshe, Meaney Michael J., Maternal programming of defensive responses through sustained effects on gene expression, Biological Psychology, 73, 1, 2006. Crossref
-
Mo Christina, Renoir Thibault, Hannan Anthony J., Stress and Glucocorticoids as Experience-Dependent Modulators of Huntington's Disease, in Stress: Physiology, Biochemistry, and Pathology, 2019. Crossref
-
Weinstock Marta, Changes Induced by Prenatal Stress in Behavior and Brain Morphology: Can They Be Prevented or Reversed?, in Perinatal Programming of Neurodevelopment, 10, 2015. Crossref
-
Chen P. J., Yan Z., Corticotropin-Releasing Factor in Brain function, in Handbook of Neurochemistry and Molecular Neurobiology, 2006. Crossref
-
Osborne Michael T., Abohashem Shady, Zureigat Hadil, Abbasi Taimur A., Tawakol Ahmed, Multimodality molecular imaging: Gaining insights into the mechanisms linking chronic stress to cardiovascular disease, Journal of Nuclear Cardiology, 28, 3, 2021. Crossref
-
Ghaemi Kerahrodi Jasmin, Michal Matthias, The fear-defense system, emotions, and oxidative stress, Redox Biology, 37, 2020. Crossref
-
Gunnar Megan, Quevedo Karina, The Neurobiology of Stress and Development, Annual Review of Psychology, 58, 1, 2007. Crossref
-
Carvalho-Netto Eduardo F., Litvin Yoav, Nunes-de-Souza Ricardo L., Blanchard D. Caroline, Blanchard Robert J., Effects of intra-PAG infusion of ovine CRF on defensive behaviors in Swiss-Webster mice, Behavioural Brain Research, 176, 2, 2007. Crossref
-
Farrokhi Catherine, Blanchard D.Caroline, Griebel Guy, Yang Mu, Gonzales Coty, Markham Chris, Blanchard Robert J., Effects of the CRF1 antagonist SSR125543A on aggressive behaviors in hamsters, Pharmacology Biochemistry and Behavior, 77, 3, 2004. Crossref
-
Berretz Gesa, Packheiser Julian, Kumsta Robert, Wolf Oliver T., Ocklenburg Sebastian, The brain under stress—A systematic review and activation likelihood estimation meta-analysis of changes in BOLD signal associated with acute stress exposure, Neuroscience & Biobehavioral Reviews, 124, 2021. Crossref
-
Pérez Miguel Á, Terreros Gonzalo, Dagnino-Subiabre Alexies, Long-term ω-3 fatty acid supplementation induces anti-stress effects and improves learning in rats, Behavioral and Brain Functions, 9, 1, 2013. Crossref
-
Meaney Michael J, Maternal Care, Gene Expression, and the Transmission of Individual Differences in Stress Reactivity Across Generations, Annual Review of Neuroscience, 24, 1, 2001. Crossref
-
Marchisella Francesca, Creutzberg Kerstin Camile, Begni Veronica, Sanson Alice, Wearick-Silva Luis Eduardo, Tractenberg Saulo Gantes, Orso Rodrigo, Kestering-Ferreira Érika, Grassi-Oliveira Rodrigo, Riva Marco Andrea, Exposure to Prenatal Stress Is Associated With an Excitatory/Inhibitory Imbalance in Rat Prefrontal Cortex and Amygdala and an Increased Risk for Emotional Dysregulation, Frontiers in Cell and Developmental Biology, 9, 2021. Crossref
-
Chen Yanmei, Ni Yiling, Zhou Jianhong, Zhou Hua, Zhong Qian, Li Xinyue, Zhang Jichuan, Ma Yuanye, Wei Jingkuan, The Amygdala Responds Rapidly to Flashes Linked to Direct Retinal Innervation: A Flash-evoked Potential Study Across Cortical and Subcortical Visual Pathways, Neuroscience Bulletin, 37, 8, 2021. Crossref
-
Roozendaal Benno, Brunson Kristen L., Holloway Brian L., McGaugh James L., Baram Tallie Z., Involvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidation, Proceedings of the National Academy of Sciences, 99, 21, 2002. Crossref
-
Sztainberg Y, Kuperman Y, Tsoory M, Lebow M, Chen A, The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1, Molecular Psychiatry, 15, 9, 2010. Crossref
-
Meaney Michael J., Szyf Moshe, Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome, Dialogues in Clinical Neuroscience, 7, 2, 2005. Crossref
-
Mitra Rupshi, Sapolsky Robert M., Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy, Proceedings of the National Academy of Sciences, 105, 14, 2008. Crossref
-
Weninger Stacie C., Dunn Adrian J., Muglia Louis J., Dikkes Pieter, Miczek Klaus A., Swiergiel Artur H., Berridge Craig W., Majzoub Joseph A., Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH, Proceedings of the National Academy of Sciences, 96, 14, 1999. Crossref
-
Bülbül Mehmet, Sinen Osman, The influence of early-life and adulthood stressors on brain neuropeptide-S system, Neuropeptides, 92, 2022. Crossref
-
Brunson K L, Avishai-Eliner S, Hatalski C G, Baram T Z, Neurobiology of the stress response early in life: evolution of a concept and the role of corticotropin releasing hormone, Molecular Psychiatry, 6, 6, 2001. Crossref
-
Lichlyter Daniel A., Krumm Zachary A., Golde Todd A., Doré Sylvain, Role of CRF and the hypothalamic‐pituitary‐adrenal axis in stroke: revisiting temporal considerations and targeting a new generation of therapeutics, The FEBS Journal, 2022. Crossref
-
Schulkin Jay, W. Gold Philip, S. McEwen Bruce, INDUCTION OF CORTICOTROPIN-RELEASING HORMONE GENE EXPRESSION BY GLUCOCORTICOIDS: IMPLICATION FOR UNDERSTANDING THE STATES OF FEAR AND ANXIETY AND ALLOSTATIC LOAD, Psychoneuroendocrinology, 23, 3, 1998. Crossref
-
Rupasinghe Rayiky, Dezsi Gabi, Ozturk Ezgi, Carron Simone, Hudson Matthew R., Casillas-Espinosa Pablo M., Jones Nigel C., Early life adversity accelerates epileptogenesis and enhances depression-like behaviors in rats, Experimental Neurology, 354, 2022. Crossref
-
Lew Jimin, Jones Sherri Lee, Caccese Christina, Orfi Isobel, Little Charlotte, Botteron Kelly N., McCracken James T., Nguyen Tuong-Vi, Developmental variation in testosterone:cortisol ratio alters cortical- and amygdala-based cognitive processes, Journal of Developmental Origins of Health and Disease, 13, 3, 2022. Crossref
-
Babicola Lucy, Ventura Rossella, D'Addario Sebastian Luca, Ielpo Donald, Andolina Diego, Di Segni Matteo, Long term effects of early life stress on HPA circuit in rodent models, Molecular and Cellular Endocrinology, 521, 2021. Crossref
-
Meaney Michael J., Liebowitz Michael L., David Leonardo E., Neurobiology of Anxiety Disorders, in Psychiatry, 2015. Crossref
-
Meaney M. J., Weaver I. C. G., Wu T., Hellstrom I., Diorio J., Szyf Moshe, Maternal Programming of Glucocorticoid Receptor Expression and HPA Responses to Stress Through DNA Methylation in the Rat, in Handbook of Neurochemistry and Molecular Neurobiology, 2007. Crossref
-
Limoges Aaron, Yarur Hector E., Tejeda Hugo A., Dynorphin/kappa opioid receptor system regulation on amygdaloid circuitry: Implications for neuropsychiatric disorders, Frontiers in Systems Neuroscience, 16, 2022. Crossref