Publication de 4 numéros par an
ISSN Imprimer: 0731-8898
ISSN En ligne: 2162-6537
Indexed in
Antioxidant Potential of Black Tea Against 7,12-Dimethylbenz(a)anthracene- Induced Oxidative Stress in Swiss Albino Mice
RÉSUMÉ
Oxygen free radicals and related reactive species have been implicated in the etiology of many diseases, such as atherosclerosis, neurodegenerative disorders, and cancer. Antioxidant enzymes exist in cells to protect against the effects of these free radicals and other oxygen-derived species, which are produced during the oxidative stress. Tea (Camellia sinensis) is the most commonly consumed beverage worldwide. Both green and black tea are known to possess many pharmacological properties, including antioxidant, antipyretic, antibacterial, and antineoplastic effects. In the present study, the preventive effects of black tea extract (BTE) was evaluated in Swiss albino mice against 7,12-dimethyl benz(a)anthracene (DMBA)-induced oxidative stress. The animals were given 0.5%, 1%, and 1.5% BTE as the sole source of drinking solution for 1 week prior to the administration of DMBA, which was given orally as a single dose of 50 mg/kg body weight. At the end of the study period, the liver, kidney, and prostate tissues were dissected out for the determination of antioxidant enzyme levels (catalase, superoxide dismutase, glutathione reductase, glutathione-S-transferase), and lipid peroxidation. A dose-dependent protective effect of BTE against DMBA-induced depletion in enzymes activity was observed in all three tissues examined. Similarly, a significant dose-dependent inhibition of the lipid peroxidation caused by DMBA was observed in the BTE-administered animals in all three tissues examined. Our results revealed that BTE provides protection against oxidative damage induced by xenobiotics.
-
Srivastava Smita, Singh Madhulika, Roy Preeti, Prasad Sahdeo, George Jasmine, Shukla Yogeshwer, Inhibitory effect of tea polyphenols on hepatic preneoplastic foci in Wistar rats, Investigational New Drugs, 27, 6, 2009. Crossref
-
Prasad Sahdeo, Kalra Neetu, Shukla Yogeshwer, Hepatoprotective effects of lupeol and mango pulp extract of carcinogen induced alteration in Swiss albino mice, Molecular Nutrition & Food Research, 51, 3, 2007. Crossref
-
George Jasmine, Nigam Nidhi, Shukla Yogeshwer, Tea: age-old beverage as an effective cancer chemopreventive agent, Oncology Reviews, 1, 4, 2008. Crossref
-
Subashini Rajakannu, Yogeeta Surinderkumar, Gnanapragasam Arunachalam, Devaki Thiruvengadam, Protective effect of Nardostachys jatamansi on oxidative injury and cellular abnormalities during doxorubicin-induced cardiac damage in rats, Journal of Pharmacy and Pharmacology, 58, 2, 2010. Crossref
-
Roy Preeti, George Jasmine, Srivastava Smita, Tyagi Shilpa, Shukla Yogeshwer, Inhibitory effects of tea polyphenols by targeting cyclooxygenase-2 through regulation of nuclear factor kappa B, Akt and p53 in rat mammary tumors, Investigational New Drugs, 29, 2, 2011. Crossref
-
Ghanem Kadry M., Nour El-Deen Amani F.H., Ramadan Manal M., Farrag Abdel Razik H., Fadel Hoda H.M., Ahdallah Nadia M., Blend infusion of some aromatic plants ameliorates carbon tetrachloride-induced hepatic damage in rats by inhibition of oxidative stress, Medical Research Journal, 10, 1, 2011. Crossref
-
Prasad Sahdeo, Kaur Jaspreet, Roy Preeti, Kalra Neetu, Shukla Yogeshwer, RETRACTED: Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells, Life Sciences, 81, 17-18, 2007. Crossref
-
Forbes-Hernández Tamara Y., Giampieri Francesca, Gasparrini Massimiliano, Mazzoni Luca, Quiles José L., Alvarez-Suarez José M., Battino Maurizio, The effects of bioactive compounds from plant foods on mitochondrial function: A focus on apoptotic mechanisms, Food and Chemical Toxicology, 68, 2014. Crossref
-
Singh Brahma N., Prateeksha , Rawat A. K. S., Bhagat R. M., Singh B. R., Black tea: Phytochemicals, cancer chemoprevention, and clinical studies, Critical Reviews in Food Science and Nutrition, 57, 7, 2017. Crossref
-
Santos C.B., Bernardino G.Z., Soares F.J., Espindola J.D., Arruda P.M.R., Paula J.R., Conceição E.C., Bara M.T.F, Preparo e caracterização de tinturas das folhas de chá verde [Camellia sinensis (L.) O. Kuntze] Theaceae, Revista Brasileira de Plantas Medicinais, 16, 4, 2014. Crossref
-
Prasad S, Kalra N, Srivastava S, Shukla Y, Regulation of oxidative stress–mediated apoptosis by diallyl sulfide in DMBA-exposed Swiss mice, Human & Experimental Toxicology, 27, 1, 2008. Crossref
-
Wang An Na, Wu Li Gen, Jia Lin Lu, Li Xiu Ling, Sun Yu Dan, Alginate-Chitosan Microspheres for Controlled Release of Tea Polyphenol, Advanced Materials Research, 152-153, 2010. Crossref
-
Shankar Sharmila, Singh Brahma N., Srivastava Rakesh K., Plant Polyphenols and Their Role in Cancer Prevention and Chemotherapy, in Nutrition, Diet and Cancer, 2012. Crossref
-
Akhouri Vivek, Kumar Arun, Kumari Manorma, Antitumour Property ofPterocarpus santalinusSeeds Against DMBA-Induced Breast Cancer in Rats, Breast Cancer: Basic and Clinical Research, 14, 2020. Crossref
-
Prasad Sahdeo, Srivastava Sanjay K., Oxidative stress and cancer: Antioxidative role of Ayurvedic plants, in Cancer, 2021. Crossref
-
Akhouri Vivek, Kumari Manorma, Kumar Arun, Therapeutic effect of Aegle marmelos fruit extract against DMBA induced breast cancer in rats, Scientific Reports, 10, 1, 2020. Crossref
-
Bozkurt Aliseydi, Gürsul Cebrail, Aydin Merve, Sayar İlyas, Karabakan Mehmet, Çikman Aytekin, The evaluation of oxidative stress parameters in the benign prostatic hyperplasia, prostatitis and prostate cancer, Ortadoğu Tıp Dergisi, 11, 3, 2019. Crossref
-
Sun Mang, Deng Ya, Cao Xining, Xiao Lu, Ding Qian, Luo Fuqing, Huang Peng, Gao Yuanyuan, Liu Mengqi, Zhao Hengguang, Effects of Natural Polyphenols on Skin and Hair Health: A Review, Molecules, 27, 22, 2022. Crossref