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Journal of Environmental Pathology, Toxicology and Oncology

Publication de 4  numéros par an

ISSN Imprimer: 0731-8898

ISSN En ligne: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Effect of Marine Mangrove Avicennia marina (Forssk.) Vierh Against Acetic Acid−Induced Ulcerative Colitis in Experimental Mice

Volume 31, Numéro 2, 2012, pp. 179-192
DOI: 10.1615/JEnvironPatholToxicolOncol.v31.i2.90
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RÉSUMÉ

Ulcerative colitis and Crohn's disease are two conditions that have many features in common and are referred as inflammatory bowel disease (IBD). Patients with IBD are predisposed to colorectal cancer. This investigation evaluates the effect of marine mangrove Avicennia marina against acetic acid−induced colitis. The treatment of A marina extract significantly decreased the colonic lipid peroxides, glutathione peroxidase, and serum nitric oxide and significantly increased the colonic and erythrocyte superoxide dismutase and glutathione levels compared with colitis control. In addition, A marina extract significantly decreased the lesion score and wet colon weight compared with colitis control. Treatment with A marina extract reflects its therapeutic activity against UC by minimal damage of colonic epithelial cells compared with colitis control during histopathologic examination. These protective role of A marina extract against UC could be attributed to the presence of higher levels of decanoic acid, diethylhydroxylamine (DEHA), pentanoic acid, pyrrolidine, 4-chlorophenyl, thiazolidinones, and arabinopyranoside (flavonoid). These findings suggest that A marina extract could be useful as a potential (natural) therapeutic agent for IBD.

CITÉ PAR
  1. V. Vinod Prabhu, C. Guruvayoorappan, Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits, International Immunopharmacology, 18, 1, 2014. Crossref

  2. Moura Fabiana Andréa, de Andrade Kívia Queiroz, dos Santos Juliana Célia Farias, Araújo Orlando Roberto Pimentel, Goulart Marília Oliveira Fonseca, Antioxidant therapy for treatment of inflammatory bowel disease: Does it work?, Redox Biology, 6, 2015. Crossref

  3. Yeom Yiseul, Kim Yuri, The Sasa quelpaertensis Leaf Extract Inhibits the Dextran Sulfate Sodium-induced Mouse Colitis Through Modulation of Antioxidant Enzyme Expression, Journal of Cancer Prevention, 20, 2, 2015. Crossref

  4. Debnath Trishna, Kim Da, Lim Beong, Natural Products as a Source of Anti-Inflammatory Agents Associated with Inflammatory Bowel Disease, Molecules, 18, 6, 2013. Crossref

  5. Mohammadi Erfan, Qujeq Durdi, Taheri Hassan, Hajian-Tilaki Karimollah, Evaluation of Serum Trace Element Levels and Superoxide Dismutase Activity in Patients with Inflammatory Bowel Disease: Translating Basic Research into Clinical Application, Biological Trace Element Research, 177, 2, 2017. Crossref

  6. Tian Tian, Wang Ziling, Zhang Jinhua, Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies, Oxidative Medicine and Cellular Longevity, 2017, 2017. Crossref

  7. Gharahkhani Azadeh, Pourjam Ebrahim, Pedram Majid, Inácio Maria Lurdes, Occurrence of Neodolichodorus persiangulfus n. sp. (Nematoda: Dolichodoridae) in mangrove forests of southern Iran, Forest Pathology, 49, 6, 2019. Crossref

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