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Journal of Environmental Pathology, Toxicology and Oncology

Publication de 4  numéros par an

ISSN Imprimer: 0731-8898

ISSN En ligne: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Antimutagenic Activity and In Vitro Anticancer Effects of Bamboo Salt on HepG2 Human Hepatoma Cells

Volume 32, Numéro 1, 2013, pp. 9-20
DOI: 10.1615/JEnvironPatholToxicolOncol.2013006370
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RÉSUMÉ

Bamboo salt is a traditional Korean baked solar salt processed by packing the solar salt in bamboo joint cases and heating it several times to high temperatures. The antimutagenic activity and in vitro anticancer effects of bamboo salt on HepG2 human hepatoma cells were investigated and compared to those of other salt samples. Although solar salt and purified salt exhibited comutagenicity with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in the Salmonella typhimurium TA100 strain, bamboo salt was associated with a lower degree of comutagenicity or antimutagenic activity. Bamboo salt baked nine times (9×) showed a greater increase in antimutagenic activity than salts baked once (1×) or three times (3×). At a concentration of 1%, the growth rate of HepG2 cells treated with 9× bamboo salt determined by a 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide (MIT) assay was reduced by 65%; this rate of inhibition was higher than that achieved with 1× baked bamboo salt (40%). Purified and solar salts had relatively lower inhibitory effects on growth rate (25% and 29%, respectively). Compared to the other salt samples, 9× bamboo salt significantly (p<0.05) induced apoptosis as determined by 4,6-diamidino-2-phenylindole (DAPI) staining and flow cytometry analysis. It also upregulated the expression of Bax, caspase-9 and caspase-3; and downregulated Bcl-2 expression. The bamboo salts, especially 9× bamboo salt, also significantly (p<0.05) downregulated the expression of inflammation-related NF-κB, iNOS, and COX-2, and upregulated the gene expression of IκB-α compared to the other salt sample.

CITÉ PAR
  1. Zhao Xin, Song Jia-Le, Jung Ok-Sang, Lim Yaung-Iee, Park Kun-Young, Chemical properties and in vivo gastric protective effects of bamboo salt, Food Science and Biotechnology, 23, 3, 2014. Crossref

  2. Jeong Jong Hee, Choi Jae-Hyeok, Kim Min Chul, Park Jae Hyeon, Herrin Jason Scott, Kim Seung Hyun, Lee Haiwon, Cho Nam-Joon, Elucidating how bamboo salt interacts with supported lipid membranes: influence of alkalinity on membrane fluidity, European Biophysics Journal, 44, 5, 2015. Crossref

  3. Ju Jaehyun, Song Jia-Le, Park Kun-Young, Antiobesity Effects of Bamboo Salt in C57BL/6 Mice, Journal of Medicinal Food, 18, 6, 2015. Crossref

  4. SUO HUAYI, SONG JIA-LE, ZHOU YALIN, LIU ZHENHU, YI RUOKUN, ZHU KAI, XIE JIE, ZHAO XIN, Induction of apoptosis in HCT-116 colon cancer cells by polysaccharide of Larimichthys crocea swim bladder, Oncology Letters, 9, 2, 2015. Crossref

  5. Kim Hee-Young, Ju Jaehyun, Lee Kyung Hee, Park Kun-Young, In vitro Anticancer Effect of Salt on HepG2 Human Hepatocellular Carcinoma Cells, Journal of the Korean Society of Food Science and Nutrition, 45, 1, 2016. Crossref

  6. Pang Liang, Zhao Xin, Liu Weiwei, Deng Jiang, Tan Xiaotong, Qiu Lihua, Anticancer Effect of Ursodeoxycholic Acid in Human Oral Squamous Carcinoma HSC-3 Cells through the Caspases, Nutrients, 7, 5, 2015. Crossref

  7. KIM JIN HYO, KIM SO-YOUNG, CHOI GEUN-HYOUNG, LEE JI-HAE, Polycyclic Aromatic Hydrocarbon Generation in Heat-Processed Sundried Salt, Journal of Food Protection, 77, 9, 2014. Crossref

  8. Zhao Xin, Pang Liang, Li Jing, Song Jia-Le, Qiu Li-Hua, Apoptosis Inducing Effects of Kuding Tea Polyphenols in Human Buccal Squamous Cell Carcinoma Cell Line BcaCD885, Nutrients, 6, 8, 2014. Crossref

  9. JEONG JONG HEE, NOH MIN-YOUNG, CHOI JAE-HYEOK, LEE HAIWON, KIM SEUNG HYUN, Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons, Experimental and Therapeutic Medicine, 11, 4, 2016. Crossref

  10. Qian Yu, Song Jia-Le, Sun Peng, Yi Ruokun, Liu Honglin, Feng Xia, Park Kun-Young, Zhao Xin, Lactobacillus casei Strain Shirota Enhances the In Vitro Antiproliferative Effect of Geniposide in Human Oral Squamous Carcinoma HSC-3 Cells, Molecules, 23, 5, 2018. Crossref

  11. Li Chong, Huang Guangbin, Tan Fang, Zhou Xianrong, Mu Jianfei, Zhao Xin, In Vitro Analysis of Antioxidant, Anticancer, and Bioactive Components of Apocynum venetum Tea Extracts, Journal of Food Quality, 2019, 2019. Crossref

  12. Cheng Zhou , Xu Hui , Wang Xiaoping , Liu Zuoye , Lactobacillus raises in vitro anticancer effect of geniposide in HSC‑3 human oral squamous cell carcinoma cells, Experimental and Therapeutic Medicine, 2017. Crossref

  13. Zeng Shi, Zhao Xin, Xu Lun-Shan, Yang Donghong, Chen Lizhao, Xu Min-Hui, Apoptosis induction effect of Apocynum venetum polyphenol on human U87 glioma cells via NF-κB pathway, Future Oncology, 15, 32, 2019. Crossref

  14. Kim Hee‐Yun, Han Dongkyun, Kim Jungeun, Yoo Min‐Sun, Lee Jin‐Soo, Kim Hyunyong, Kim Hyung‐Min, Jeong Hyun‐Ja, An anti‐cancer effect of Sambou bamboo salt TM in melanoma skin cancer both in vivo and in vitro models , Journal of Food Biochemistry, 45, 9, 2021. Crossref

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