Abonnement à la biblothèque: Guest
Critical Reviews™ in Immunology

Publication de 6  numéros par an

ISSN Imprimer: 1040-8401

ISSN En ligne: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

FcR-Mediated Inhibition of Cell Activation and Other Forms of Coinhibition

Volume 18, Numéro 6, 1998, pp. 525-544
DOI: 10.1615/CritRevImmunol.v18.i6.30
Get accessGet access

RÉSUMÉ

The tripartite inactivation model proposed that coaggregation of the B cell antigen receptor (BCR) with the Fc receptor (FcR) by antigen and specific IgG antibody complexes explained the Fc-dependent inhibition of immune responses by antibody. This model has since been substantiated by many observations and its impact on studies of immune regulation has been threefold: (1) IgG antibody, via FcγRIIB, mediates inhibition of cell activation in many cell types, demonstrating the general importance of this mechanism in immune regulation; (2) FcγRIIB was the first receptor described that regulates immune responses by coinhibition, that is, regulation as a result of interaction between activating receptors (BCR, TCR, FcεRI, FcγRIII, FcγRIIA) and inhibitory receptors (FcγRIIB, CTLA4, CD5, CD22, p58/70/140 KIR, gp49Bl/gp91, Ly49A/C/E/F/G, NKG2-A/B, APCR, Fas (CD95), TGFβ-R, TNF-R, IFNγ-R, and others). The list of coinhibitors is expanding, just as the list of costimulators has grown. Tolerance through multiple coinhibitors implies that Signal 1 alone is not tolerogenic; and (3) Studies of FcγRIIB coinhibitory mechanisms have pointed the way to potential general inhibitory signaling pathways used by many receptors, involving the competing effects of various kinases and phosphatases, and other competitive events. Investigations of FcγRIIB physiologic function and of other coinhibitory receptors, together with recent biochemical analyses, give an initial understanding of the biology of these inhibitory receptors. Paradoxes within and between theoretical constructs, functional observations, and mechanistic studies point to critical questions for future study.

CITÉ PAR
  1. Philosof-Oppenheimer Rachel, Hampe Christiane S., Schlessinger Karni, Fridkin Mati, Pecht Israel, An immunoreceptor tyrosine-based inhibitory motif, with serine at site Y-2, binds SH2-domain-containing phosphatases, European Journal of Biochemistry, 267, 3, 2000. Crossref

  2. Ledder Ruth G., Timperley Andrea S., Friswell Melissa K., Macfarlane Sandra, McBain Andrew J., Coaggregation between and among human intestinal and oral bacteria, FEMS Microbiology Ecology, 66, 3, 2008. Crossref

  3. Kajiya Mikihito, Giro Gabriela, Taubman Martin A., Han Xiaozhe, Mayer Marcia P. A., Kawai Toshihisa, Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease, Journal of Oral Microbiology, 2, 1, 2010. Crossref

  4. Helft Julie, Jacquet Alexandra, Joncker Nathalie T., Grandjean Isabelle, Dorothée Guillaume, Kissenpfennig Adrien, Malissen Bernard, Matzinger Polly, Lantz Olivier, Antigen-specific T-T interactions regulate CD4 T-cell expansion, Blood, 112, 4, 2008. Crossref

  5. Kumpel Belinda M., On the mechanism of tolerance to the Rh D antigen mediated by passive anti-D (Rh D prophylaxis), Immunology Letters, 82, 1-2, 2002. Crossref

  6. Mechanism of Intravenous Immune Globulin Therapy, New England Journal of Medicine, 341, 1, 1999. Crossref

  7. Kumpel Belinda M., In vivo studies of monoclonal anti-D and the mechanism of immune suppression, Transfusion Clinique et Biologique, 9, 1, 2002. Crossref

  8. Yang Lijun, Shen Lian, Shao Yuehu, Zhao Qing, Zhang Wei, Cytoplasmic domain of human Fcalpha/mu receptor is required for ligand internalization, Cellular Immunology, 258, 1, 2009. Crossref

  9. Nezlin Roald, A quantitative approach to the determination of antigen in immune complexes, Journal of Immunological Methods, 237, 1-2, 2000. Crossref

  10. Kumpel Belinda M, Monoclonal anti-D development programme, Transplant Immunology, 10, 2-3, 2002. Crossref

  11. Mattsson Nancy, Duzevik Eliza Grlickova, Pelsue Stephen C., Expansion of CD22lo B cells in the spleen of autoimmune-prone flaky skin mice, Cellular Immunology, 234, 2, 2005. Crossref

  12. Coggeshall K.M, Nakamura Koji, Phee Hyewon, How do inhibitory phosphatases work?, Molecular Immunology, 39, 9, 2002. Crossref

  13. Preissler Mark T, Kaiser Laura, Drake James R, Gosselin Edmund J, Low-Level Signaling Generated by FcγRIIB-B Cell Receptor Co-Ligation Establishes a State of Global B Cell Receptor Nonresponsiveness, Immunological Investigations, 34, 1, 2005. Crossref

  14. Kumpel Belinda M., Elson Christopher J., Mechanism of anti-D-mediated immune suppression – a paradox awaiting resolution?, Trends in Immunology, 22, 1, 2001. Crossref

  15. Anderson Colin C., Conceptual Models in Immunity/Tolerance: Application to Transplantation, in Immunobiology of Organ Transplantation, 2004. Crossref

  16. Prager Elisabeth, Staffler Günther, Majdic Otto, Säemann Marcus D., Godár Samuel, Zlabinger Gerhard J., Stockinger Hannes, Induction of Hyporesponsiveness and Impaired T Lymphocyte Activation by the CD31 Receptor:Ligand Pathway in T Cells, The Journal of Immunology, 166, 4, 2001. Crossref

  17. Tizard Ian, The Protective Properties of Milk and Colostrum in Non-Human Species, in Advances in Nutritional Research Volume 10, 2010. Crossref

  18. Huggins Jennifer, Pellegrin Tina, Felgar Raymond E., Wei Chungwen, Brown Miguel, Zheng Bo, Milner Eric C. B., Bernstein Steven H., Sanz Ignacio, Zand Martin S., CpG DNA activation and plasma-cell differentiation of CD27− naive human B cells, Blood, 109, 4, 2007. Crossref

  19. Nakamura Koji, Malykhin Alexander, Coggeshall K. Mark, The Src homology 2 domain–containing inositol 5-phosphatase negatively regulates Fcγ receptor–mediated phagocytosis through immunoreceptor tyrosine-based activation motif–bearing phagocytic receptors, Blood, 100, 9, 2002. Crossref

  20. Kumar Santosh, Sarkar Pabak, Sim Malcolm J. W., Rajagopalan Sumati, Vogel Steven S., Long Eric O., A Single Amino Acid Change in Inhibitory Killer Cell Ig-like Receptor Results in Constitutive Receptor Self-Association and Phosphorylation, The Journal of Immunology, 194, 2, 2015. Crossref

  21. Koenig-Marrony Severine, Soulas Pauline, Julien Sylvie, Knapp Anne-Marie, Garaud Jean-Claude, Martin Thierry, Pasquali Jean-Louis, Natural Autoreactive B Cells in Transgenic Mice Reproduce an Apparent Paradox to the Clonal Tolerance Theory, The Journal of Immunology, 166, 3, 2001. Crossref

  22. Sinclair N. R. StC., Fc-Signalling in the Modulation of Immune Responses by Passive Antibody, Scandinavian Journal of Immunology, 53, 4, 2001. Crossref

  23. Khandelwal Sanjay, Barnes Ayiesha, Rauova Lubica, Sarkar Amrita, Rux Ann H., Yarovoi Serge V., Zaitsev S. Sergei, Lambris John D., Myoung Sooho S., Johnson Alexandra, Lee Grace M., Duarte Madelaine, Poncz Mortimer, Arepally Gowthami M., Cines Douglas B., Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes, Blood, 138, 21, 2021. Crossref

  24. Chakrabarti Atis, Kervinen Jukka, Müller Egbert, Tanaka Toru, Muranaka Kazuaki, Analytical Characterization of Monoclonal Antibodies with Novel Fc Receptor-Based Chromatography Technique, in Monoclonal Antibodies, 2021. Crossref

  25. Long Eric O., Sik Kim Hun, Liu Dongfang, Peterson Mary E., Rajagopalan Sumati, Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition, Annual Review of Immunology, 31, 1, 2013. Crossref

  26. Vearing Christopher, Lee Fook-Thean, Wimmer-Kleikamp Sabine, Spirkoska Violeta, To Catherine, Stylianou Con, Spanevello Mark, Brechbiel Martin, Boyd Andrew W., Scott Andrew M., Lackmann Martin, Concurrent Binding of Anti-EphA3 Antibody and Ephrin-A5 Amplifies EphA3 Signaling and Downstream Responses: Potential as EphA3-Specific Tumor-Targeting Reagents, Cancer Research, 65, 15, 2005. Crossref

  27. Kepley Christopher L., Taghavi Sharven, Mackay Graham, Zhu Daocheng, Morel Penelope A., Zhang Ke, Ryan John J., Satin Leslie S., Zhang Min, Pandolfi Pier P., Saxon Andrew, Co-aggregation of FcγRII with FcϵRI on Human Mast Cells Inhibits Antigen-induced Secretion and Involves SHIP-Grb2-Dok Complexes, Journal of Biological Chemistry, 279, 34, 2004. Crossref

  28. Matzinger Polly, Autoimmunity: Are we asking the right question?, Frontiers in Immunology, 13, 2022. Crossref

  29. Tanguay Debra, Pavlovic Sandra, Piatelli Michael J., Bartek Jiri, Chiles Thomas C., B Cell Antigen Receptor-Mediated Activation of Cyclin-Dependent Retinoblastoma Protein Kinases and Inhibition by Co-Cross-Linking with Fcγ Receptors, The Journal of Immunology, 163, 6, 1999. Crossref

Prochains articles

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections Prix et politiques d'abonnement Begell House Contactez-nous Language English 中文 Русский Português German French Spain