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Critical Reviews™ in Immunology

Publication de 6  numéros par an

ISSN Imprimer: 1040-8401

ISSN En ligne: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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Innate Antiviral Immunity against Dengue Virus

Volume 35, Numéro 3, 2015, pp. 253-260
DOI: 10.1615/CritRevImmunol.2015014251
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RÉSUMÉ

Dengue virus (DENV), the most prevalent mosquito-borne viral diseases in humans worldwide, causes dengue fever, a mild form of the disease, as well as dengue hemorrhagic fever/dengue shock syndrome, a more severe form which can be life-threatening. The four serotypes of DENV (DENV1-4) are positive-sense, single stranded RNA virus belonging to the Flaviviridae family and are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Together, they are estimated to cause almost 100 million symptomatic cases, 2.1 million cases of dengue hemorrhagic fever/dengue shock syndrome, and 21,000 deaths per year worldwide. There are currently no effective vaccines or antiviral treatment for DENV. Innate immune defenses play a key role in controlling DENV infection in the early stages. Herein we review the innate antiviral immunity against DENV by delineating the intracellular mechanisms of the immune response and the evasion mechanisms evolved by the virus. A better understanding of the innate immune response will impact the development of novel animal models, antiviral drugs as well as potential targeted adjuvants for DENV vaccines.

MOTS CLÉS: Interferon, STAT1, STAT2, IRF, ISG
CITÉ PAR
  1. Zonneveld Rens, Roosblad Jimmy, Staveren Jan Willem van, Wilschut Jan C., Vreden Stephen G.S., Codrington John, Three atypical lethal cases associated with acute Zika virus infection in Suriname, IDCases, 5, 2016. Crossref

  2. Vroon Pieter, Roosblad Jimmy, Poese Fauzia, Wilschut Jan, Codrington John, Vreden Stephen, Zonneveld Rens, Severity of acute Zika virus infection: A prospective emergency room surveillance study during the 2015–2016 outbreak in Suriname, IDCases, 10, 2017. Crossref

  3. Zeidler Julianna, Fernandes-Siqueira Lorena, Barbosa Glauce, Da Poian Andrea, Non-Canonical Roles of Dengue Virus Non-Structural Proteins, Viruses, 9, 3, 2017. Crossref

  4. Mathew Anuja, Humanized mouse models to study human cell-mediated and humoral responses to dengue virus, Current Opinion in Virology, 25, 2017. Crossref

  5. Piret Jocelyne, Carbonneau Julie, Rhéaume Chantal, Baz Mariana, Boivin Guy, Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice, Journal of General Virology , 99, 2, 2018. Crossref

  6. Meyer Bjoern, Ly Hinh, Immunosuppression by hemorrhagic fever-causing viruses, Oncotarget, 6, 42, 2015. Crossref

  7. Müller Claudia, Hrynkiewicz Rafał, Bębnowska Dominika, Maldonado Jaime, Baratelli Massimiliano, Köllner Bernd, Niedźwiedzka-Rystwej Paulina, Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination, Vaccines, 9, 3, 2021. Crossref

  8. Barrows Nicholas J., Campos Rafael K., Liao Kuo-Chieh, Prasanth K. Reddisiva, Soto-Acosta Ruben, Yeh Shih-Chia, Schott-Lerner Geraldine, Pompon Julien, Sessions October M., Bradrick Shelton S., Garcia-Blanco Mariano A., Biochemistry and Molecular Biology of Flaviviruses, Chemical Reviews, 118, 8, 2018. Crossref

  9. Lo Yu-Chih, Perng Guey Chuen, Novel concept on antiviral strategies to dengue, Current Opinion in Virology, 18, 2016. Crossref

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