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Critical Reviews™ in Therapeutic Drug Carrier Systems

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ISSN Imprimer: 0743-4863

ISSN En ligne: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

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Recent Advances in the Stabilization of Proteins Encapsulated in Injectable PLGA Delivery Systems

Volume 19, Numéro 1, 2002, 26 pages
DOI: 10.1615/CritRevTherDrugCarrierSyst.v19.i1.20
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RÉSUMÉ

Injectable controlled-release systems based on biodegradable copolymers of lactic and glycolic acids (PLGAs) have become widely used for delivery of protein therapeutics and vaccine antigens. Over the last five years, great strides have been made toward overcoming the difficulty of stabilizing PLGA-encapsulated proteins. In addition to stabilizing proteins during encapsulation with anhydrous methods, two approaches have proven highly effective to stabilize proteins during 1-month release incubation under physiological conditions: protein complexation with zinc and control of PLGA microclimate pH with antacid excipients. Described here are recent advances in the stabilization of proteins encapsulated in PLGA delivery systems.

CITÉ PAR
  1. Daoud‐Mahammed S., Grossiord J. L., Bergua T., Amiel C., Couvreur P., Gref R., Self‐assembling cyclodextrin based hydrogels for the sustained delivery of hydrophobic drugs, Journal of Biomedical Materials Research Part A, 86A, 3, 2008. Crossref

  2. Ding Amy G., Schwendeman Steven P., Determination of water‐soluble acid distribution in poly(lactide‐co‐glycolide), Journal of Pharmaceutical Sciences, 93, 2, 2004. Crossref

  3. Pawar Rajendra, Ben-Ari Alon, Domb Abraham J, Protein and peptide parenteral controlled delivery, Expert Opinion on Biological Therapy, 4, 8, 2004. Crossref

  4. Ulery Bret D., Phanse Yashdeep, Sinha Avanti, Wannemuehler Michael J., Narasimhan Balaji, Bellaire Bryan H., Polymer Chemistry Influences Monocytic Uptake of Polyanhydride Nanospheres, Pharmaceutical Research, 26, 3, 2009. Crossref

  5. Sharma Sameer, Mukkur T.K.S., Benson Heather A.E., Chen Yan, Pharmaceutical Aspects of Intranasal Delivery of Vaccines Using Particulate Systems, Journal of Pharmaceutical Sciences, 98, 3, 2009. Crossref

  6. Kaye Richard S., Purewal Tol S., Alpar H. Oya, Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies, Journal of Pharmaceutical Sciences, 98, 11, 2009. Crossref

  7. Taluja Ajay, Youn Yu Seok, Bae You Han, Novel approaches in microparticulate PLGA delivery systems encapsulating proteins, Journal of Materials Chemistry, 17, 38, 2007. Crossref

  8. Xie Jingwei, Wang Chi-Hwa, Encapsulation of proteins in biodegradable polymeric microparticles using electrospray in the Taylor cone-jet mode, Biotechnology and Bioengineering, 97, 5, 2007. Crossref

  9. McDowell A., McLeod B. J., Rades T., Tucker I. G., Application of pharmaceutical drug delivery for biological control of the common brushtail possum in New Zealand: a review, Wildlife Research, 33, 8, 2006. Crossref

  10. Lassalle V.L., Ferreira M.L., Experimental problems in the application of UV/visible based methods as the quantification tool for the entrapped/released insulin from PLGA carriers, Journal of Chemical Technology & Biotechnology, 84, 9, 2009. Crossref

  11. Berkland Cory, Pollauf Emily, Raman Chandrashekar, Silverman Roshelle, Kim Kyekyoon (Kevin), Pack Daniel W., Macromolecule Release from Monodisperse PLG Microspheres: Control of Release Rates and Investigation of Release Mechanism, Journal of Pharmaceutical Sciences, 96, 5, 2007. Crossref

  12. Duan Ke, Wang Rizhi, Surface modifications of bone implants through wet chemistry, Journal of Materials Chemistry, 16, 24, 2006. Crossref

  13. Hou Sijian, McCauley Laurie K., Ma Peter X., Synthesis and Erosion Properties of PEG-Containing Polyanhydrides, Macromolecular Bioscience, 7, 5, 2007. Crossref

  14. Varde Neelesh K, Pack Daniel W, Microspheres for controlled release drug delivery, Expert Opinion on Biological Therapy, 4, 1, 2004. Crossref

  15. Castellanos Ingrid J., Flores Giselle, Griebenow Kai, Effect of cyclodextrins on α-chymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation, Journal of Pharmaceutical Sciences, 95, 4, 2006. Crossref

  16. Mohammadi Yousef, Jabbari Esmaiel, Monte Carlo Simulation of Degradation of Porous Poly(lactide) Scaffolds, 1, Macromolecular Theory and Simulations, 15, 9, 2006. Crossref

  17. Tamilvanan Shunmugaperumal, Progress in Design of Biodegradable Polymer-Based Microspheres for Parenteral Controlled Delivery of Therapeutic Peptide/Protein, in Pharmaceutical Sciences Encyclopedia, 2010. Crossref

  18. Klose D., Azaroual N., Siepmann F., Vermeersch G., Siepmann J., Towards More Realistic In Vitro Release Measurement Techniques for Biodegradable Microparticles, Pharmaceutical Research, 26, 3, 2009. Crossref

  19. Castellanos Ingrid J., Al-Azzam Wasfi, Griebenow Kai, Effect of the Covalent Modification with Poly(ethylene glycol) on α-Chymotrypsin Stability upon Encapsulation in Poly(lactic-co-glycolic) Microspheres, Journal of Pharmaceutical Sciences, 94, 2, 2005. Crossref

  20. Baroli Biancamaria, From natural bone grafts to tissue engineering therapeutics: Brainstorming on pharmaceutical formulative requirements and challenges, Journal of Pharmaceutical Sciences, 98, 4, 2009. Crossref

  21. Wang Ye, Gao Jian-Qing, Zheng Cai-Hong, Xu Dong-Hang, Liang Wen-Quan, Biodegradable and complexed microspheres used for sustained delivery and activity protection of SOD, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 79B, 1, 2006. Crossref

  22. Houchin M.L., Topp E.M., Chemical Degradation of Peptides and Proteins in PLGA: A Review of Reactions and Mechanisms, Journal of Pharmaceutical Sciences, 97, 7, 2008. Crossref

  23. Hurtado-López Pepi, Murdan Sudaxshina, An investigation into the adjuvanticity and immunogenicity of zein microspheres being researched as drug and vaccine carriers, Journal of Pharmacy and Pharmacology, 58, 6, 2010. Crossref

  24. Wischke Christian, Zhang Ying, Mittal Sachin, Schwendeman Steven P., Development of PLGA-Based Injectable Delivery Systems For Hydrophobic Fenretinide, Pharmaceutical Research, 27, 10, 2010. Crossref

  25. Ennett Alessandra B., Kaigler Darnell, Mooney David J., Temporally regulated delivery of VEGFin vitro andin vivo, Journal of Biomedical Materials Research Part A, 79A, 1, 2006. Crossref

  26. Houchin M. L., Topp E. M., Physical properties of PLGA films during polymer degradation, Journal of Applied Polymer Science, 114, 5, 2009. Crossref

  27. Lin Chien-Chi, Metters Andrew T., Enhanced Protein Delivery from Photopolymerized Hydrogels Using a Pseudospecific Metal Chelating Ligand, Pharmaceutical Research, 23, 3, 2006. Crossref

  28. Teixidó Meritxell, Giralt Ernest, The role of peptides in blood-brain barrier nanotechnology, Journal of Peptide Science, 14, 2, 2008. Crossref

  29. Wu Fei, Jin Tuo, Polymer-Based Sustained-Release Dosage Forms for Protein Drugs, Challenges, and Recent Advances, AAPS PharmSciTech, 9, 4, 2008. Crossref

  30. Wei Guobao, Ma Peter X., Nanostructured Biomaterials for Regeneration, Advanced Functional Materials, 18, 22, 2008. Crossref

  31. Zhang Ying, Sophocleous Andreas M., Schwendeman Steven P., Inhibition of Peptide Acylation in PLGA Microspheres with Water-soluble Divalent Cationic Salts, Pharmaceutical Research, 26, 8, 2009. Crossref

  32. Yeo Yoon, Park Kinam, Characterization of reservoir-type microcapsules made by the solvent exchange method, AAPS PharmSciTech, 5, 4, 2004. Crossref

  33. Katare Yogesh K., Panda Amulya K., Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particles, European Journal of Pharmaceutical Sciences, 28, 3, 2006. Crossref

  34. Whittlesey Kevin J., Shea Lonnie D., Delivery systems for small molecule drugs, proteins, and DNA: the neuroscience/biomaterial interface, Experimental Neurology, 190, 1, 2004. Crossref

  35. Bilati Ugo, Allémann Eric, Doelker Eric, Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles, European Journal of Pharmaceutics and Biopharmaceutics, 59, 3, 2005. Crossref

  36. Göpferich A, Becker C, Drug Delivery, in Tissue Engineering, 2007. Crossref

  37. Giavaresi G., Tschon M., Borsari V., Daly J.H., Liggat J.J., Fini M., Bonazzi V., Nicolini A., Carpi A., Morra M., Cassinelli C., Giardino R., New polymers for drug delivery systems in orthopaedics: in vivo biocompatibility evaluation, Biomedicine & Pharmacotherapy, 58, 8, 2004. Crossref

  38. Wei Gang, Lu Li Fang, Lu Wei Yue, Stabilization of recombinant human growth hormone against emulsification-induced aggregation by Pluronic surfactants during microencapsulation, International Journal of Pharmaceutics, 338, 1-2, 2007. Crossref

  39. De Temmerman Marie-Luce, Rejman Joanna, Demeester Jo, Irvine Darrell J., Gander Bruno, De Smedt Stefaan C., Particulate vaccines: on the quest for optimal delivery and immune response, Drug Discovery Today, 16, 13-14, 2011. Crossref

  40. Klose D., Siepmann F., Elkharraz K., Siepmann J., PLGA-based drug delivery systems: Importance of the type of drug and device geometry, International Journal of Pharmaceutics, 354, 1-2, 2008. Crossref

  41. Park Kinam, Yeo Yoon, Microencapsulation of Protein Drugs, in Tissue Engineering And Novel Delivery Systems, 2003. Crossref

  42. Johansen Pål, Martínez Gómez Julia M, Gander Bruno, Development of synthetic biodegradable microparticulate vaccines: a roller coaster story, Expert Review of Vaccines, 6, 4, 2007. Crossref

  43. Dziubla Thomas D., Shuvaev Vladimir V., Hong Nan Kang, Hawkins Brian J., Madesh Muniswamy, Takano Hajime, Simone Eric, Nakada Marian T., Fisher Aron, Albelda Steven M., Muzykantov Vladimir R., Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies, Biomaterials, 29, 2, 2008. Crossref

  44. Yeo Yoon, Park Kinam, A new microencapsulation method using an ultrasonic atomizer based on interfacial solvent exchange, Journal of Controlled Release, 100, 3, 2004. Crossref

  45. Gaudana Ripal, Khurana Varun, Parenky Ashwin, Mitra Ashim K., Encapsulation of Protein-Polysaccharide HIP Complex in Polymeric Nanoparticles, Journal of Drug Delivery, 2011, 2011. Crossref

  46. Olivier Jean-Christophe, Drug transport to brain with targeted nanoparticles, NeuroRX, 2, 1, 2005. Crossref

  47. Sakai Tsutomu, Kohno Hideo, Ishihara Tsutomu, Higaki Megumu, Saito Saburo, Matsushima Masato, Mizushima Yutaka, Kitahara Kenji, Treatment of experimental autoimmune uveoretinitis with poly(lactic acid) nanoparticles encapsulating betamethasone phosphate, Experimental Eye Research, 82, 4, 2006. Crossref

  48. Pei Ping, Horan Michael P., Hille Russ, Hemann Craig F., Schwendeman Steven P., Mallery Susan R., Reduced nonprotein thiols inhibit activation and function of MMP-9: Implications for chemoprevention, Free Radical Biology and Medicine, 41, 8, 2006. Crossref

  49. Lightowlers Marshall W., Eradication of Taenia solium cysticercosis: A role for vaccination of pigs, International Journal for Parasitology, 40, 10, 2010. Crossref

  50. Panyam Jayanth, Dali Manisha M., Sahoo Sanjeeb K., Ma Wenxue, Chakravarthi Sudhir S., Amidon Gordon L., Levy Robert J., Labhasetwar Vinod, Polymer degradation and in vitro release of a model protein from poly(d,l-lactide-co-glycolide) nano- and microparticles, Journal of Controlled Release, 92, 1-2, 2003. Crossref

  51. Sophocleous Andreas M., Zhang Ying, Schwendeman Steven P., A new class of inhibitors of peptide sorption and acylation in PLGA, Journal of Controlled Release, 137, 3, 2009. Crossref

  52. Katare Yogesh K., Muthukumaran T., Panda Amulya K., Influence of particle size, antigen load, dose and additional adjuvant on the immune response from antigen loaded PLA microparticles, International Journal of Pharmaceutics, 301, 1-2, 2005. Crossref

  53. Jang Jae-Hyung, Shea Lonnie D, Controllable delivery of non-viral DNA from porous scaffolds, Journal of Controlled Release, 86, 1, 2003. Crossref

  54. Salem Aliasger K., Behlke Mark A., SiRNA Delivery Vehicles, in RNA Interference, 2010. Crossref

  55. Giri Jyotsnendu, Li Wan-Ju, Tuan Rocky S., Cicerone Marcus T., Stabilization of Proteins by Nanoencapsulation in Sugar-Glass for Tissue Engineering and Drug Delivery Applications, Advanced Materials, 23, 42, 2011. Crossref

  56. Hinds Kenneth D., Campbell Kathleen M., Holland Kathleen M., Lewis Danny H., Piché Claude A., Schmidt Paul G., PEGylated insulin in PLGA microparticles. In vivo and in vitro analysis, Journal of Controlled Release, 104, 3, 2005. Crossref

  57. Hirose Keiichi, Marui Akira, Arai Yoshio, Nomura Takamasa, Inoue Sachiko, Kaneda Kozo, Kamitani Tetsuya, Fujita Masatoshi, Mitsuyama Masao, Tabata Yasuhiko, Komeda Masashi, Sustained-release vancomycin sheet may help to prevent prosthetic graft methicillin-resistant Staphylococcus aureus infection, Journal of Vascular Surgery, 44, 2, 2006. Crossref

  58. Houchin M.L., Neuenswander S.A., Topp E.M., Effect of excipients on PLGA film degradation and the stability of an incorporated peptide, Journal of Controlled Release, 117, 3, 2007. Crossref

  59. Van Tomme Sophie R., De Geest Bruno G., Braeckmans Kevin, De Smedt Stefaan C., Siepmann Florence, Siepmann Juergen, van Nostrum Cornelus F., Hennink Wim E., Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching, Journal of Controlled Release, 110, 1, 2005. Crossref

  60. Ghassemi A.H., van Steenbergen M.J., Talsma H., van Nostrum C.F., Jiskoot W., Crommelin D.J.A., Hennink W.E., Preparation and characterization of protein loaded microspheres based on a hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid), Journal of Controlled Release, 138, 1, 2009. Crossref

  61. Chorny Michael, Fishbein Ilia, Forbes Scott, Alferiev Ivan, Magnetic nanoparticles for targeted vascular delivery, IUBMB Life, 63, 8, 2011. Crossref

  62. van Nostrum Cornelus, Hein van Steenis Jan, Hennink Wim, Fast Biodegradable Polymers, in Reflexive Polymers and Hydrogels, 2004. Crossref

  63. Yan Qinyi, Major Terry C., Bartlett Robert H., Meyerhoff Mark E., Intravascular glucose/lactate sensors prepared with nitric oxide releasing poly(lactide-co-glycolide)-based coatings for enhanced biocompatibility, Biosensors and Bioelectronics, 26, 11, 2011. Crossref

  64. Jin Tuo, Zhu Jiahao, Wu Fei, Yuan Weien, Geng Lee L., Zhu Hua, Preparing polymer-based sustained-release systems without exposing proteins to water–oil or water–air interfaces and cross-linking reagents, Journal of Controlled Release, 128, 1, 2008. Crossref

  65. Koennings S., Sapin A., Blunk T., Menei P., Goepferich A., Towards controlled release of BDNF — Manufacturing strategies for protein-loaded lipid implants and biocompatibility evaluation in the brain, Journal of Controlled Release, 119, 2, 2007. Crossref

  66. Cui Chengji, Stevens Vernon C., Schwendeman Steven P., Injectable polymer microspheres enhance immunogenicity of a contraceptive peptide vaccine, Vaccine, 25, 3, 2007. Crossref

  67. Thote Amol J., Gupta Ram B., Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release, Nanomedicine: Nanotechnology, Biology and Medicine, 1, 1, 2005. Crossref

  68. Dorati Rossella, Genta Ida, Colonna Claudia, Modena Tiziana, Pavanetto Franca, Perugini Paola, Conti Bice, Investigation of the degradation behaviour of poly(ethylene glycol-co-d,l-lactide) copolymer, Polymer Degradation and Stability, 92, 9, 2007. Crossref

  69. Li Lei, Schwendeman Steven P., Mapping neutral microclimate pH in PLGA microspheres, Journal of Controlled Release, 101, 1-3, 2005. Crossref

  70. Peters Ron, Lebouille Jeromme, Plum Bart, Schoenmakers Peter, van der Wal Sjoerd, Hydrolytic degradation of poly(d,l-lactide-co-glycolide 50/50)-di-acrylate network as studied by liquid chromatography–mass spectrometry, Polymer Degradation and Stability, 96, 9, 2011. Crossref

  71. Mohl Silke, Winter Gerhard, Continuous Release of rh-Interferon α-2a from Triglyceride Implants: Storage Stability of the Dosage Forms, Pharmaceutical Development and Technology, 11, 1, 2006. Crossref

  72. Houchin M.L., Heppert K., Topp E.M., Deamidation, acylation and proteolysis of a model peptide in PLGA films, Journal of Controlled Release, 112, 1, 2006. Crossref

  73. Segal Ehud, Satchi-Fainaro Ronit, Design and development of polymer conjugates as anti-angiogenic agents, Advanced Drug Delivery Reviews, 61, 13, 2009. Crossref

  74. Ishihara Tsutomu, Izumo Nobuo, Higaki Megumu, Shimada Emi, Hagi Tomomi, Mine Lisa, Ogawa Yasuaki, Mizushima Yutaka, Role of zinc in formulation of PLGA/PLA nanoparticles encapsulating betamethasone phosphate and its release profile, Journal of Controlled Release, 105, 1-2, 2005. Crossref

  75. Jiang Bin, Zhang Gehan, Brey Eric M., Dual delivery of chlorhexidine and platelet-derived growth factor-BB for enhanced wound healing and infection control, Acta Biomaterialia, 9, 2, 2013. Crossref

  76. León-Rodríguez L., Luzardo-Álvarez A., Blanco-Méndez J., Lamas J., Leiro J., Biodegradable microparticles covalently linked to surface antigens of the scuticociliate parasite P. dicentrarchi promote innate immune responses in vitro, Fish & Shellfish Immunology, 34, 1, 2013. Crossref

  77. Zhang Ying, Schwendeman Steven P., Minimizing acylation of peptides in PLGA microspheres, Journal of Controlled Release, 162, 1, 2012. Crossref

  78. Wang Xiao-Peng, Chen Tian-Ning, Yang Zhan-Xiao, Modeling and simulation of drug delivery from a new type of biodegradable polymer micro-device, Sensors and Actuators A: Physical, 133, 2, 2007. Crossref

  79. Giavaresi Gianluca, Tschon Matilde, Daly John H., Liggat John J., Sutherland Duncan S., Agheli Hossein, Fini Milena, Torricelli Paola, Giardino Roberto, In vitro and in vivo response to nanotopographically-modified surfaces of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and polycaprolactone, Journal of Biomaterials Science, Polymer Edition, 17, 12, 2006. Crossref

  80. Ko Du Young, Shinde Usha Pramod, Yeon Bora, Jeong Byeongmoon, Recent progress of in situ formed gels for biomedical applications, Progress in Polymer Science, 38, 3-4, 2013. Crossref

  81. Thote Amol J., Gupta Ram B., Formation of Nanoparticles of a Hydrophilic Drug Using Supercritical Carbon Dioxide and Microencapsulation for Sustained Release, Disease-a-Month, 51, 6, 2005. Crossref

  82. Riddle Kathryn W., Mooney David J., Role of poly(lactide-co-glycolide) particle size on gas-foamed scaffolds, Journal of Biomaterials Science, Polymer Edition, 15, 12, 2004. Crossref

  83. Gaudana Ripal, Gokulgandhi Mitan, Khurana Varun, Kwatra Deep, Mitra Ashim K., Design and evaluation of a novel nanoparticulate-based formulation encapsulating a HIP complex of lysozyme, Pharmaceutical Development and Technology, 18, 3, 2013. Crossref

  84. Wang Xiaopeng, Chen Tianning, Yang Zhanxiao, Wang Wanjun, Study on structural optimum design of implantable drug delivery micro-system, Simulation Modelling Practice and Theory, 15, 1, 2007. Crossref

  85. Desai Kashappa-Goud H., Schwendeman Steven P., Active self-healing encapsulation of vaccine antigens in PLGA microspheres, Journal of Controlled Release, 165, 1, 2013. Crossref

  86. Agrawal Himanshu, Thacker Nipa, Misra Ambikanandan, Parenteral Delivery of Peptides and Proteins, in Challenges in Delivery of Therapeutic Genomics and Proteomics, 2011. Crossref

  87. Dailey Lea Ann, Kissel Thomas, New poly(lactic-co-glycolic acid) derivatives: Modular polymers with tailored properties, Drug Discovery Today: Technologies, 2, 1, 2005. Crossref

  88. Liu Yajun, Ghassemi Amir H., Hennink Wim E., Schwendeman Steven P., The microclimate pH in poly(d,l-lactide-co-hydroxymethyl glycolide) microspheres during biodegradation, Biomaterials, 33, 30, 2012. Crossref

  89. Prasad Shashi, Cody Virginia, Saucier-Sawyer Jennifer K., Fadel Tarek R., Edelson Richard L., Birchall Martin A., Hanlon Douglas J., Optimization of Stability, Encapsulation, Release, and Cross-Priming of Tumor Antigen-Containing PLGA Nanoparticles, Pharmaceutical Research, 29, 9, 2012. Crossref

  90. Uesugi Yoshiko, Kawata Hiroyuki, Saito Yoshihiko, Tabata Yasuhiko, Ultrasound-responsive thrombus treatment with zinc-stabilized gelatin nano-complexes of tissue-type plasminogen activator, Journal of Drug Targeting, 20, 3, 2012. Crossref

  91. Kang Han Chang, Lee Ji Eun, Bae You Han, Nanoscaled buffering zone of charged (PLGA)n-b-bPEI micelles in acidic microclimate for potential protein delivery application, Journal of Controlled Release, 160, 3, 2012. Crossref

  92. Boraey Mohammed A., Vehring Reinhard, Diffusion controlled formation of microparticles, Journal of Aerosol Science, 67, 2014. Crossref

  93. Gupta Surashree Sen, Ghosh Mahua, Preparation and characterisation of protein based nanocapsules of bioactive lipids, Journal of Food Engineering, 121, 2014. Crossref

  94. Gao Xiujun, Zhou Ping, Yang Rui, Yang De, Zhang Ning, Protein-loaded comb-shape copolymer-based pH-responsive nanoparticles to improve the stability of proteins, Journal of Materials Chemistry B, 1, 38, 2013. Crossref

  95. Falconi Mirella, Focaroli Stefano, Teti Gabriella, Salvatore Viviana, Durante Sandra, Nicolini Benedetta, Orienti Isabella, Novel PLA microspheres with hydrophilic and bioadhesive surfaces for the controlled delivery of fenretinide, Journal of Microencapsulation, 31, 1, 2014. Crossref

  96. Milacic Vesna, Schwendeman Steven P., Lysozyme Release and Polymer Erosion Behavior of Injectable Implants Prepared from PLGA-PEG Block Copolymers and PLGA/PLGA-PEG Blends, Pharmaceutical Research, 31, 2, 2014. Crossref

  97. Reinhold Samuel E., Schwendeman Steven P., Effect of Polymer Porosity on Aqueous Self-Healing Encapsulation of Proteins in PLGA Microspheres, Macromolecular Bioscience, 13, 12, 2013. Crossref

  98. Sophocleous Andreas M., Desai Kashappa-Goud H., Mazzara J. Maxwell, Tong Ling, Cheng Ji-Xin, Olsen Karl F., Schwendeman Steven P., The nature of peptide interactions with acid end-group PLGAs and facile aqueous-based microencapsulation of therapeutic peptides, Journal of Controlled Release, 172, 3, 2013. Crossref

  99. Olivier Jean-Christophe, Pereira de Oliveira Manuela, Nanoparticulate Systems for Central Nervous System Drug Delivery, in Nanoparticulate Drug Delivery Systems, 20075578, 2007. Crossref

  100. Handa Hitesh, Brisbois Elizabeth J., Major Terry C., Refahiyat Lahdan, Amoako Kagya A., Annich Gail M., Bartlett Robert H., Meyerhoff Mark E., Invitro and in vivo study of sustained nitric oxide release coating using diazeniumdiolate-doped poly(vinyl chloride) matrix with poly(lactide-co-glycolide) additive, Journal of Materials Chemistry B, 1, 29, 2013. Crossref

  101. Yi Xiang, Manickam Devika S., Brynskikh Anna, Kabanov Alexander V., Agile delivery of protein therapeutics to CNS, Journal of Controlled Release, 190, 2014. Crossref

  102. Clark Amanda, Milbrandt Todd A, Hilt J Zach, Puleo David A, Retention of insulin-like growth factor I bioactivity during the fabrication of sintered polymeric scaffolds, Biomedical Materials, 9, 2, 2014. Crossref

  103. Yang Fan, Neeley William, Moore Michael, Karp Jeffrey, Shukla Anita, Langer Robert, Tissue Engineering: The Therapeutic Strategy of the Twenty-First Century, in Nanotechnology and Regenerative Engineering, 2014. Crossref

  104. Zhou Ping, An Tong, Zhao Chuan, Li Yuan, Li Rongshan, Yang Rui, Wang Yinsong, Gao Xiujun, Lactosylated PLGA nanoparticles containing ϵ-polylysine for the sustained release and liver-targeted delivery of the negatively charged proteins, International Journal of Pharmaceutics, 478, 2, 2015. Crossref

  105. Kazazi-Hyseni Filis, Landin Mariana, Lathuile Audrey, Veldhuis Gert J., Rahimian Sima, Hennink Wim E., Kok Robbert Jan, van Nostrum Cornelus F., Computer Modeling Assisted Design of Monodisperse PLGA Microspheres with Controlled Porosity Affords Zero Order Release of an Encapsulated Macromolecule for 3 Months, Pharmaceutical Research, 31, 10, 2014. Crossref

  106. Shah Ronak B., Schwendeman Steven P., A biomimetic approach to active self-microencapsulation of proteins in PLGA, Journal of Controlled Release, 196, 2014. Crossref

  107. Schwendeman Steven P., Shah Ronak B., Bailey Brittany A., Schwendeman Anna S., Injectable controlled release depots for large molecules, Journal of Controlled Release, 190, 2014. Crossref

  108. Kang Jian, Wu Fei, Cai Yunpeng, Xu Mingxin, He Mu, Yuan Weien, Development of Recombinant Human Growth Hormone (rhGH) sustained-release microspheres by a low temperature aqueous phase/aqueous phase emulsion method, European Journal of Pharmaceutical Sciences, 62, 2014. Crossref

  109. Schädlich Andreas, Kempe Sabine, Mäder Karsten, Non-invasive in vivo characterization of microclimate pH inside in situ forming PLGA implants using multispectral fluorescence imaging, Journal of Controlled Release, 179, 2014. Crossref

  110. Xia Yujie, Pack Daniel W., Pulsatile Protein Release from Monodisperse Liquid-Core Microcapsules of Controllable Shell Thickness, Pharmaceutical Research, 31, 11, 2014. Crossref

  111. Vaishya Ravi, Khurana Varun, Patel Sulabh, Mitra Ashim K, Long-term delivery of protein therapeutics, Expert Opinion on Drug Delivery, 12, 3, 2015. Crossref

  112. Ma J., Meng J., Simonet M., Stingelin N., Peijs T., Sukhorukov G. B., Biodegradable fibre scaffolds incorporating water-soluble drugs and proteins, Journal of Materials Science: Materials in Medicine, 26, 7, 2015. Crossref

  113. Keles Hakan, Naylor Andrew, Clegg Francis, Sammon Chris, Investigation of factors influencing the hydrolytic degradation of single PLGA microparticles, Polymer Degradation and Stability, 119, 2015. Crossref

  114. Lupi A., Perugini P., Genta I., Modena T., Conti B., Casado B., Cetta G., Pavanetto F., Iadarola P., Biodegradable microspheres for prolidase delivery to human cultured fibroblasts, Journal of Pharmacy and Pharmacology, 56, 5, 2010. Crossref

  115. Chaturvedi Sumit Kumar, Alam Parvez, Khan Javed Masood, Siddiqui Mohd. Khursheed, Kalaiarasan Ponnusamy, Subbarao Naidu, Ahmad Zeeshan, Khan Rizwan Hasan, Biophysical insight into the anti-amyloidogenic behavior of taurine, International Journal of Biological Macromolecules, 80, 2015. Crossref

  116. Conti B., Dorati R., Colonna C., Genta I., Effects of ionizing radiation sterilization on microparticulate drug delivery systems based on poly-α-hydroxyacids: an overview, Journal of Drug Delivery Science and Technology, 19, 2, 2009. Crossref

  117. Cicerone Marcus T., Pikal Michael J., Qian Ken K., Stabilization of proteins in solid form, Advanced Drug Delivery Reviews, 93, 2015. Crossref

  118. Shirangi Mehrnoosh, Hennink Wim E., Somsen Govert W., van Nostrum Cornelus F., Identification and Assessment of Octreotide Acylation in Polyester Microspheres by LC–MS/MS, Pharmaceutical Research, 32, 9, 2015. Crossref

  119. Jorgensen Lene, Hostrup Susanne, Moeller Eva Horn, Grohganz Holger, Recent trends in stabilising peptides and proteins in pharmaceutical formulation – considerations in the choice of excipients, Expert Opinion on Drug Delivery, 6, 11, 2009. Crossref

  120. Srinivasan C., Katare Y. K., Muthukumaran T., Panda A. K., Effect of additives on encapsulation efficiency, stability and bioactivity of entrapped lysozyme from biodegradable polymer particles, Journal of Microencapsulation, 22, 2, 2005. Crossref

  121. Naha Pratap C., Kanchan V., Manna P. K., Panda Amulya K., Improved bioavailability of orally delivered insulin using Eudragit-L30D coated PLGA microparticles, Journal of Microencapsulation, 25, 4, 2008. Crossref

  122. Kharel Sharad, Lee Wei Li, Lee Xuan Yi, Loo Say Chye Joachim, Osmogen-Mediated One-Step Technique of Fabricating Hollow Microparticles for Encapsulation and Delivery of Bioactive Molecules, Macromolecular Bioscience, 17, 4, 2017. Crossref

  123. Taki Aya, Smooker Peter, Small Wonders—The Use of Nanoparticles for Delivering Antigen, Vaccines, 3, 3, 2015. Crossref

  124. Gayakwad Sanjay G., Bejugam Naveen K., Akhavein Nima, Uddin Nasir A., Oettinger Carl E, D'Souza Martin J., Formulation andin vitrocharacterization of spray-dried antisense oligonucleotide to NF-κB encapsulated albumin microspheres, Journal of Microencapsulation, 26, 8, 2009. Crossref

  125. Langer Robert, Shukla Anita, Moore Michael, Yang Fan, Neeley William, Karp Jeffrey, Tissue Engineering, in Nanotechnology and Tissue Engineering, 2008. Crossref

  126. Shenoy Dinesh B., D'Souza Reshma J., Tiwari Sandip B., Udupa N., Potential Applications of Polymeric Microsphere Suspension as Subcutaneous Depot for Insulin, Drug Development and Industrial Pharmacy, 29, 5, 2003. Crossref

  127. Chu Zhaowei, Li Xiaoming, Li Ying, Zheng Quan, Feng Chenglong, Guo Meng, Ding Xili, Feng Wentao, Gao Yuanming, Yao Jie, Chen Xiaofang, Wang Lizhen, Fan Yubo, Effects of different fluid shear stress patterns on the in vitro degradation of poly(lactide-co-glycolide) acid membranes, Journal of Biomedical Materials Research Part A, 105, 1, 2017. Crossref

  128. Sharma Rajeev, Mody Nishi, Dubey Surbhi, Agrawal Udita, Vyas Suresh, Polyester Nano- and Microsystems for Vaccine Delivery, in Handbook of Polyester Drug Delivery Systems, 2016. Crossref

  129. Rafi Md., Singh Surinder M., Kanchan Vibhu, Anish C. K., Panda Amulya K., Controlled release of bioactive recombinant human growth hormone from PLGA microparticles, Journal of Microencapsulation, 27, 6, 2010. Crossref

  130. Chu Zhaowei, Zheng Quan, Guo Meng, Yao Jie, Xu Peng, Feng Wentao, Hou Yongzhao, Zhou Gang, Wang Lizhen, Li Xiaoming, Fan Yubo, The effect of fluid shear stress on thein vitrodegradation of poly(lactide-co-glycolide) acid membranes, Journal of Biomedical Materials Research Part A, 104, 9, 2016. Crossref

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  133. Li Ying, Chu Zhaowei, Li Xiaoming, Ding Xili, Guo Meng, Zhao Haoran, Yao Jie, Wang Lizhen, Cai Qiang, Fan Yubo, The effect of mechanical loads on the degradation of aliphatic biodegradable polyesters, Regenerative Biomaterials, 4, 3, 2017. Crossref

  134. Wu Fei, Dai Lili, Geng Lee, Zhu Hua, Jin Tuo, Practically feasible production of sustained-release microspheres of granulocyte-macrophage colony-stimulating factor (rhGM-CSF), Journal of Controlled Release, 259, 2017. Crossref

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  139. O'Hagan Derek T., Valiante Nicholas M., Recent advances in the discovery and delivery of vaccine adjuvants, Nature Reviews Drug Discovery, 2, 9, 2003. Crossref

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  149. Kim Kyekyoon Kevin, Pack Daniel W., Microspheres for Drug Delivery, in BioMEMS and Biomedical Nanotechnology, 2006. Crossref

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