Current Status of Radiation Therapy for the Management of Rectal Cancer

William Rule; Jeffrey  Meyer

doi:10.1615/CritRevOncog.v17.i4.30

Critical Reviews™ in Oncogenesis

Éditeur en chef: Benjamin Bonavida (open in a new tab)

Publication de 4 numéros par an

ISSN Imprimer: 0893-9675

ISSN En ligne: 2162-6448

Indexed in

Current Status of Radiation Therapy for the Management of Rectal Cancer

Volume 17, Numéro 4, 2012, pp. 331-343

DOI: 10.1615/CritRevOncog.v17.i4.30

Get access

William Rule
Department of Radiation Oncology, Mayo Clinic-Arizona, Phoenix, AZ

Jeffrey Meyer
Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX

RÉSUMÉ

Neoadjuvant chemoradiation for stage II and III rectal adenocarcinoma patients is delivered on a routine basis. This treatment paradigm, built on decades of clinical study, is continuously evolving. While multiple radiosensitizers have gained a great deal of interest over the past couple of decades, 5-fluorouracil still remains as the standard radiosensitizing agent. Long-course preoperative chemoradiotherapy is the current standard of care in the Unites States, but short-course hypofractionated preoperative radiotherapy is advocated by some investigators. This review will discuss the current standard of care in the preoperative setting for patients with rectal cancer and will also examine the novel ways in which investigators are modifying this regimen in an effort to improve patient outcomes.

MOTS CLÉS: rectal cancer, radiotherapy, chemoradiation

CITÉ PAR

Peng Yi-Fan, Tumor regression grades: Potential outcome predictor of locally advanced rectal adenocarcinoma after preoperative radiotherapy, World Journal of Gastroenterology, 21, 6, 2015. Crossref
Wu Xiao-Yu, Wu Zhen-Feng, Cao Qin-Hong, Chen Che, Chen Zhi-Wei, Xu Zhe, Li Wei-Su, Liu Fu-Kun, Yao Xue-Quan, Li Gang, Insulin-like growth factor receptor-1 overexpression is associated with poor response of rectal cancers to radiotherapy, World Journal of Gastroenterology, 20, 43, 2014. Crossref
Chen Junqi, Ning Chengyun, Zhou Zhengnan, Yu Peng, Zhu Ye, Tan Guoxin, Mao Chuanbin, Nanomaterials as photothermal therapeutic agents, Progress in Materials Science, 99, 2019. Crossref
Nasrolahi Hamid, Mirzaei Sepideh, Mohammadianpanah Mohammad, Bananzadeh Ali Mohammad, Mokhtari Maral, Sasani Mohammad Reza, Mosalaei Ahmad, Omidvari Shapour, Ansari Mansour, Ahmadloo Niloofar, Hamedi Seyed Hasan, Khanjani Nezhat, Efficacy and Feasibility of Adding Induction Chemotherapy to Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer: A Phase II Clinical Trial, Annals of Coloproctology, 35, 5, 2019. Crossref
Hosseini Sare, Nguyen NamPhong, Mohammadianpanah Mohammad, Mirzaei Sepideh, Bananzadeh Ali Mohammad, Predictive Significance of Mucinous Histology on Pathologic Complete Response Rate Following Capecitabine-Based Neoadjuvant Chemoradiation in Rectal Cancer: a Comparative Study, Journal of Gastrointestinal Cancer, 50, 4, 2019. Crossref

625 Vues d'articles 45 Téléchargements d'articles Métrique

625 VUES 45 TÉLÉCHARGEMENTS 5 Crossref CITATIONS Google
Scholar CITATIONS

Articles avec un contenu similaire:

Biology of Rectal Cancer−The Rationale for Targeted Therapy Critical Reviews™ in Oncogenesis, Vol.17, 2012, issue 4
Sean Dineen

Twenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward? Critical Reviews™ in Oncogenesis, Vol.20, 2015, issue 3-4
Elizabeth Lawlor, Poul H. Sorensen

Deciphering Tumor Growth by Clonal Analysis Critical Reviews™ in Oncogenesis, Vol.19, 2014, issue 5
Gregory Driessens

Critical Concepts in the Oncogenesis of Adenocarcionoma of the Rectum Critical Reviews™ in Oncogenesis, Vol.17, 2012, issue 4
Sergio Huerta

Theranostic Nanostructures for Ovarian Cancer Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.36, 2019, issue 4
Bankuru Navyatha, Seema Nara

Dernier numéro

Machine Evaluation of Catchment Area Relevance through Text Mining Philip A. Arlen, Joseph Chakko, Geoffrey DeGennaro, Erin Kobetz, Brandon Mahal Oral Cavity Squamous Cell Carcinoma: Review of Pathology, Diagnosis, and Management Benjamin J. Rich, Stuart E. Samuels, Gregory A. Azzam, Gregory Kubicek, Laura Freedman Surgical Management of the Neck in Oral Cavity Squamous Cell Carcinoma Olivia Mihulka, Eric Nisenbaum, Elizabeth Nicolli Convolutional Neural Networks for Glioma Segmentation and Prognosis: A Systematic Review Janette Herr, Radka Stoyanova, Eric Albert Mellon Proton Beam Therapy for Breast Cancer Seraphina Choi, Isabella Dreyfuss, Crystal Seldon Taswell, Jonathan Cyriac, Michael Butkus, Cristiane Takita Management of Advanced Medullary Thyroid Carcinoma: Current Systemic Therapy Options Mark A. Jara Disparities in Electronic Cigarette Use: A Narrative Review Kyle Edwards, Aysswarya Manoharan, Taghrid Asfar, Samuel Kareff, Gilberto Lopes, Estelamari Rodriguez, Coral Olazagasti The Genetic Paradigm of Hereditary Breast and Ovarian Cancer (HBOC) in the Afro-Caribbean Population Danielle Cerbon, Daphanie Taylor, Priscila Barreto-Coelho, Estelamari Rodriguez, Matthew Schlumbrecht, Judith Hurley, Sophia H.L. George

Prochains articles

Neuroplasticity: Pathophysiology and Role in Major Depressive Disorder Rama Rao Malla, Sreeharshini Kadiyala, Priyamvada Bhamidipati IMMUNE EVASION IN CANCER IS REGULATED BY THE TUMOR-ASOCIATED MACROPHAGES (TAMS): TARGETING TAMS Megan Jung, Benjamin Bonavida Disparities in Electronic Cigarette Use: A Narrative Review Kyle Edwards, Aysswarya Manoharan, Taghrid Asfar, Samuel Kareff, Gilberto Lopes, Estelamari Rodriguez, Coral Olazagasti Advanced Medullary Thyroid Carcinoma: The Current Systemic Therapy Options Mark Jara Proton Beam Therapy for Breast Cancer Seraphina Choi, Crystal Taswell, Isabella Dreyfuss, Jonathan Cyriac, Michael Butkus, Cristiane Takita The Genetic Paradigm of Hereditary Breast and Ovarian Cancer in The Afro-Caribbean Population Danielle Cerbon, Daphnie Taylor, Priscila Barreto Coelho, Estelamari Rodriguez, Matthew Schlumbrecht, Judith Hurley, Sophia George