Publication de 12 numéros par an
ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344
Indexed in
Antioxidant and Anti-inflammatory Properties of New Medicinal Fungus, Auriculoscypha anacardiicola D.A.Reid et Manim. (Agaricomycetideae), from India
RÉSUMÉ
Antioxidant and anti-inflammatory activities of the aqueous-ethanolic extract of Auriculoscypha anacardiicola fruiting bodies were investigated. Antioxidant activity of the extract was evaluated using DPPH, superoxide anion, FRAP, nitric oxide scavenging and lipid peroxidation inhibition assays. The extract was found to be a potent free radical scavenger and antioxidant. The extract showed significant DPPH scavenging activity (IC50: 31.36±2 μg/mL), ferric reducing antioxidant power (IC50: 3.4±0.5 μg/mL) and lipid peroxidation inhibiting activity (IC50: 79.81±2.77 μg/mL). Anti-inflammatory activity of the extract was determined using carrageenan induced acute and formalin induced chronic inflammatory models in Swiss albino mice. The extract showed profound acute and chronic anti-inflammatory activity. The extract at 500 mg/kg body weight showed higher anti-inflammatory activity than the standard reference drug diclofenac, administered at 10 mg/kg body weight, for both acute and chronic inflammation in mice. This is the first report of the medicinal properties of A. anacardiicola.
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He Mao-Qiang, Zhao Rui-Lin, Hyde Kevin D., Begerow Dominik, Kemler Martin, Yurkov Andrey, McKenzie Eric H. C., Raspé Olivier, Kakishima Makoto, Sánchez-Ramírez Santiago, Vellinga Else C., Halling Roy, Papp Viktor, Zmitrovich Ivan V., Buyck Bart, Ertz Damien, Wijayawardene Nalin N., Cui Bao-Kai, Schoutteten Nathan, Liu Xin-Zhan, Li Tai-Hui, Yao Yi-Jian, Zhu Xin-Yu, Liu An-Qi, Li Guo-Jie, Zhang Ming-Zhe, Ling Zhi-Lin, Cao Bin, Antonín Vladimír, Boekhout Teun, da Silva Bianca Denise Barbosa, De Crop Eske, Decock Cony, Dima Bálint, Dutta Arun Kumar, Fell Jack W., Geml József, Ghobad-Nejhad Masoomeh, Giachini Admir J., Gibertoni Tatiana B., Gorjón Sergio P., Haelewaters Danny, He Shuang-Hui, Hodkinson Brendan P., Horak Egon, Hoshino Tamotsu, Justo Alfredo, Lim Young Woon, Menolli Nelson, Mešić Armin, Moncalvo Jean-Marc, Mueller Gregory M., Nagy László G., Nilsson R. Henrik, Noordeloos Machiel, Nuytinck Jorinde, Orihara Takamichi, Ratchadawan Cheewangkoon, Rajchenberg Mario, Silva-Filho Alexandre G. S., Sulzbacher Marcelo Aloisio, Tkalčec Zdenko, Valenzuela Ricardo, Verbeken Annemieke, Vizzini Alfredo, Wartchow Felipe, Wei Tie-Zheng, Weiß Michael, Zhao Chang-Lin, Kirk Paul M., Notes, outline and divergence times of Basidiomycota, Fungal Diversity, 99, 1, 2019. Crossref