Publication de 12 numéros par an
ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
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The Efficacy and Toxicity of Using the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), and Its Products in Chemotherapy (Review)
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RÉSUMÉ
Around the world, cancer patients often combine conventional anticancer treatment with complementary alternative medicines derived from natural sources such as fungi and mushrooms, including the popular lingzhi or reishi medicinal mushroom Ganoderma lucidum. Many studies to date have described the anticancer properties of G. lucidum, which are attributed to its major pharmacologically bioactive compounds, such as terpenoids and polysaccharides. Moreover, several scientific observations have suggested a potential beneficial therapeutic strategy using G. lucidum in combination with chemotherapeutic agents to improve therapeutic outcome. However, to my knowledge, no systematic review has been conducted in this area. Therefore, this review summarizes the current knowledge on G. lucidum or its individual components in relation to chemotherapeutic efficacy, ability to reverse multidrug resistance, and chemotherapeutic toxicity.
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Zhu Pei-Li, Fu Xiu-Qiong, Li Jun-Kui, Tse Anfernee Kai-Wing, Guo Hui, Yin Cheng-Le, Chou Ji-Yao, Wang Ya-Ping, Liu Yu-Xi, Chen Ying-Jie, Hossen Muhammad Jahangir, Zhang Yi, Pan Si-Yuan, Zhao Zong-Jie, Yu Zhi-Ling, Antrodia camphorata Mycelia Exert Anti-liver Cancer Effects and Inhibit STAT3 Signaling in vitro and in vivo, Frontiers in Pharmacology, 9, 2018. Crossref
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Liu Qian, Tie Lu, Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Diabetes, in Ganoderma and Health, 1182, 2019. Crossref
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Alhazmi Hassan A., Najmi Asim, Javed Sadique A., Sultana Shahnaz, Al Bratty Mohammed, Makeen Hafiz A., Meraya Abdulkarim M., Ahsan Waquar, Mohan Syam, Taha Manal M. E., Khalid Asaad, Medicinal Plants and Isolated Molecules Demonstrating Immunomodulation Activity as Potential Alternative Therapies for Viral Diseases Including COVID-19, Frontiers in Immunology, 12, 2021. Crossref
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Deng Y., Ma J., Tang D., Zhang Q., Dynamic biomarkers indicate the immunological benefits provided by Ganoderma spore powder in post-operative breast and lung cancer patients, Clinical and Translational Oncology, 23, 7, 2021. Crossref
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Oztopuz Ozlem, Coskun Ozlem, Buyuk Basak, Alterations in aquaporin gene expression level on cyclophosphamide-induced cardiac injury and possible protective role of Ganoderma lucidum, Biologia, 76, 10, 2021. Crossref
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Bin-Jumah May Nasser, Nadeem Muhammad Shahid, Gilani Sadaf Jamal, Imam Syed Sarim, Alshehri Sultan, Kazmi Imran, Novelkaraya gum micro-particles loaded Ganoderma lucidum polysaccharide regulate sex hormones, oxidative stress and inflammatory cytokine levels in cadmium induced testicular toxicity in experimental animals, International Journal of Biological Macromolecules, 194, 2022. Crossref
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Cao Liping, Jin Hongliu, Liang Qi, Yang Haiyi, Li Shuguang, Liu Zhicheng, Yuan Zhongwen, A new anti-tumor cytotoxic triterpene from Ganoderma lucidum, Natural Product Research, 36, 16, 2022. Crossref