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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Safety Evaluation of an Aqueous Extract of Termitomyces robustus (Agaricomycetes) in Wistar Rats

Volume 21, Numéro 2, 2019, pp. 193-203
DOI: 10.1615/IntJMedMushrooms.2018029737
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RÉSUMÉ

Termitomyces robustus is an edible and highly nutritious wild Basidiomycetes mushroom. It is used in ethnomedicine for treating malnutrition-related diseases, rheumatism, diarrhea, gonorrhea, anemia, and hypertension. Despite the tremendous use of this delicious edible mushroom as a source of nutrients, no comprehensive literature describes its safety and toxicity profiles. Therefore, this study evaluated the toxicity profile of an aqueous T. robustus extract in rats. In the acute toxicity test, male and female rats were orally administered daily a single dose of up to 10 g/kg extract. In the subacute toxicity test, male rats were orally administered the T. robustus extract at graded doses of 500, 1000, and 1500 mg/kg for 14 days. No mortality or any signs of toxicity were observed in the acute toxicity study, indicating that the median lethal dose (LD50) of T. robustus is greater than 10 g/kg. In the subacute toxicity study, T. robustus had no effect (P > 0.05) on hemoglobin, packed cell volume, red blood cell, white blood cell, alanine aminotransferase, alkaline phosphatase, neutrophil, lymphocyte, or lipid profile parameters in any of the rats. However, significant differences (P < 0.05) were noted in alanine aminotransferase, eosinophils, basophils, monocytes, platelets, urea, creatinine, and electrolytes in the tested groups when compared to values from the control group. No histopathological alterations or changes were observed in the liver or kidneys of the rats. This study established that an aqueous extract of T. robustus is nontoxic and therefore safe for consumption at the tested doses.

CITÉ PAR
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  2. Ekweogu Celestine Nwabu, Ude Victor Chibueze, Nwankpa Promise, Emmanuel Okezie, Ugbogu Eziuche Amadike, Ameliorative effect of aqueous leaf extract of Solanum aethiopicum on phenylhydrazine-induced anaemia and toxicity in rats, Toxicological Research, 36, 3, 2020. Crossref

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  4. Mbanaso Eberechukwu, Nwankwo Azubuike, Ijioma Solomon Nnah, Emmanuel Okezie, Ugbogu Eziuche Amadike, Nwagbara Ngozi, Ugwuanyi Kingsley, Haematoprotective and red blood cell membrane stabilizing effects of Justicia carnae leaf extracts in sodium nitrate-treated rats, Journal of Basic and Clinical Physiology and Pharmacology, 2020. Crossref

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