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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antimalarial and Hepatoprotective Effects of Crude Ethanolic Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.)P.Karst. (Higher Basidiomycetes), in Plasmodium berghei-Infected Mice

Volume 14, Issue 5, 2012, pp. 459-466
DOI: 10.1615/IntJMedMushr.v14.i5.30
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ABSTRACT

This study was aimed at investigating the in vivo antimalarial activity (using some biochemical indices) of crude aqueous extracts of the fruiting bodies of Ganoderma lucidum, a mushroom with well-established medicinal properties. A rodent malaria parasite, Plasmodium berghei (1 × 107), was inoculated intraperitoneally into Swiss albino mice. The test groups were administered G. lucidum extract and chloroquine (CQ, as standard drug), while the control groups were administered the same amount of distilled water by an intragastric tube once daily. The antimalarial activity of the extract was investigated from the suppressive, curative, and prophylactic effects of the extract on parasite growth. Serum aminotransferases (AST and ALT), alkaline phosphatase (ALP), and gamma glutamine transpeptidase (γ-GT) levels monitored following the 4-day suppressive test were significantly reduced, with a corresponding significant increase in the livers of mice treated with the extract compared with infected untreated mice. The results obtained from this study provide scientific justification in an animal model of malaria that an ethanolic extract of G. lucidum possesses potent antimalarial activity and also could help ameliorate the attendant Plasmodium-induced liver damage due to malarial infection.

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  1. Banik Samudra Prosad, Khowala Suman, Pal Chiranjib, Mukherjee Soumya, Proteomic Approaches to Identify Novel Therapeutics and Nutraceuticals from Filamentous Fungi, in Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods, 2015. Crossref

  2. Ma Ke, Li Li, Bao Li, He Luwei, Sun Chen, Zhou Bing, Si Shuyi, Liu Hongwei, Six new 3,4-seco-27-norlanostane triterpenes from the medicinal mushroom Ganoderma boninense and their antiplasmodial activity and agonistic activity to LXRβ, Tetrahedron, 71, 12, 2015. Crossref

  3. Oluba Olarewaju M., Josiah Sunday J., Adebisi Kayode E., Ojeaburu Sam I., Chukwu Onyeneke E., Antiplasmodial and antioxidant activities of chloroform extract of Ganoderma lucidum fruit body in Plasmodium berghei-infected mice, Oriental Pharmacy and Experimental Medicine, 17, 4, 2017. Crossref

  4. Wang Jue, Cao Bin, Zhao Haiping, Feng Juan, Emerging Roles of Ganoderma Lucidum in Anti-Aging, Aging and disease, 8, 6, 2017. Crossref

  5. Oluba Olarewaju Michael, Erythrocyte Lipid and Antioxidant Changes in Plasmodium falciparum-infected Children Attending Mother and Child Hospital in Akure, Nigeria, Pakistan Journal of Biological Sciences, 22, 6, 2019. Crossref

  6. Shedoeva Aleksandra, Leavesley David, Upton Zee, Fan Chen, Wound Healing and the Use of Medicinal Plants, Evidence-Based Complementary and Alternative Medicine, 2019, 2019. Crossref

  7. Oluba Olarewaju M., Ganoderma terpenoid extract exhibited anti-plasmodial activity by a mechanism involving reduction in erythrocyte and hepatic lipids in Plasmodium berghei infected mice, Lipids in Health and Disease, 18, 1, 2019. Crossref

  8. Oluba Olarewaju M., Akpor Oghenerobor B., Adebiyi Feyikemi D., Josiah Sunday J., Alabi Olayinka O., Shoyombo Ayoola O., Olusola Augustine O., Effects of co-administration of Ganoderma terpenoid extract with chloroquine on inflammatory markers and antioxidant status in Plasmodium berghei-infected mice, Journal of Integrative Medicine, 18, 6, 2020. Crossref

  9. Ma Ke, Ren Jinwei, Han Junjie, Bao Li, Li Li, Yao Yijian, Sun Chen, Zhou Bing, Liu Hongwei, Ganoboninketals A–C, Antiplasmodial 3,4-seco-27-Norlanostane Triterpenes from Ganoderma boninense Pat., Journal of Natural Products, 77, 8, 2014. Crossref

  10. Happi Gervais Mouthé, Meikeu Livine Zemo, Sikam Klev Gaïtan, Dzouemo Liliane Clotilde, Wansi Jean Duplex, Mushrooms (Basidiomycetes) as a significant source of biologically active compounds for malaria control, Natural Resources for Human Health, 2, 2, 2022. Crossref

  11. Mkhize Senzosenkosi S., Machaba Kgothatso E., Simelane Mthokozisi B. C., Pooe Ofentse J., Mushroom‐Derived Products as an Alternative Antimalarial Therapeutics: A Review, in Drug Development for Malaria, 2022. Crossref

  12. Lenzi Juliana, Costa Tania Maria , Filho Hercílio Higino da Silva , Alberton Michele Debiasi , Goulart Juliane Araújo Greinert , Tavares Lorena Benathar Ballod, Antiprotozoal Activity of Mycelial Extracts of Several Medicinal Agaricomycetes Mushrooms against Giardia duodenalis , International Journal of Medicinal Mushrooms, 24, 12, 2022. Crossref

  13. Moussa Ashaimaa Y., Xu Baojun, A narrative review on inhibitory effects of edible mushrooms against malaria and tuberculosis-the world’s deadliest diseases, Food Science and Human Wellness, 12, 4, 2023. Crossref

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