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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antitumor Activity and Hematopoietic Response of a b-Glucan Extracted from an Edible and Medicinal Mushroom Sparassis crispa Wulf.: Fr. (Aphyllophoromycetideae)

Volume 4, Issue 1, 2002, 14 pages
DOI: 10.1615/IntJMedMushr.v4.i1.20
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ABSTRACT

Sparassis crispa Wulf.: Fr. is an edible and medicinal mushroom recently cultivated in Japan. It contains a high content (~ 40%) of 6-branched 1,3-b-D-glucan showing antitumor activity. Oral administration of the (b-glucan fraction CA1, extracted with cold sodium hydroxide, enhanced the hematopoietic response in cyclophosphamide (CY)-induced leukopenic mice assessed by white blood cell count. Analyzing the leukocyte population by flow cytometry, the rate of leukocyte recovery in CY-administered mice was different in each population, such as granulocyte, monocyte, natural killer cell, В cell, Т cell, and so on. Administration of CA1 modulated the recovery rate of each population. In Peyer's patches, recovery of the T/B ratio was faster than in the control group. In in vitro, CY-treated spleen cell culture, interleukin-6 and interferon-g production was enhanced by CA1 treatment. These facts strongly suggested that the enhanced hematopoietic response by CA1 is due to enhanced cytokine production.

CITED BY
  1. El Enshasy Hesham A., Hatti-Kaul Rajni, Mushroom immunomodulators: unique molecules with unlimited applications, Trends in Biotechnology, 31, 12, 2013. Crossref

  2. Hida Toshie H., Kawaminami Hiromi, Ishibashi Ken-ichi, Miura Noriko N., Adachi Yoshiyuki, Yadomae Toshiro, Ohno Naohito, Effect of GM-CSF on cytokine induction by soluble β-glucan SCGin vitroin β-glucan-treated mice, Microbiology and Immunology, 53, 7, 2009. Crossref

  3. Harada Toshie, Ohno Naohito, Contribution of dectin-1 and granulocyte macrophage–colony stimulating factor (GM-CSF) to immunomodulating actions of β-glucan, International Immunopharmacology, 8, 4, 2008. Crossref

  4. Kakutani Ryo, Adachi Yoshiyuki, Kajiura Hideki, Takata Hiroki, Kuriki Takashi, Ohno Naohito, The effect of orally administered glycogen on anti-tumor activity and natural killer cell activity in mice, International Immunopharmacology, 12, 1, 2012. Crossref

  5. Harada Toshie, Kawaminami Hiromi, Miura Noriko N., Adachi Yoshiyuki, Nakajima Mitsuhiro, Yadomae Toshiro, Ohno Naohito, Mechanism of Enhanced Hematopoietic Response by Soluble β-Glucan SCG in Cyclophosphamide-Treated Mice, Microbiology and Immunology, 50, 9, 2006. Crossref

  6. Moradali Mohammad-Fata, Mostafavi Hossein, Ghods Shirin, Hedjaroude Ghorban-Ali, Immunomodulating and anticancer agents in the realm of macromycetes fungi (macrofungi), International Immunopharmacology, 7, 6, 2007. Crossref

  7. Ohno N., Yeast and Fungal Polysaccharides, in Comprehensive Glycoscience, 2007. Crossref

  8. Nameda Sachiko, Harada Toshie, Miura Noriko N., Adachi Yoshiyuki, Yadomae Toshiro, Nakajima Mitsuhiro, Ohno Naohito, Enhanced Cytokine Synthesis of Leukocytes by a β‐Glucan Preparation, SCG, Extracted from a Medicinal Mushroom,Sparassis crispa, Immunopharmacology and Immunotoxicology, 25, 3, 2003. Crossref

  9. Sánchez Carmen, Bioactives from Mushroom and Their Application, in Food Bioactives, 2017. Crossref

  10. Nie Shaoping, Cui Steve W., Xie Mingyong, Beta-Glucans and Their Derivatives, in Bioactive Polysaccharides, 2018. Crossref

  11. Borchers Andrea T., Keen Carl L., Gershwin M. Eric, Mushrooms, Tumors, and Immunity: An Update, Experimental Biology and Medicine, 229, 5, 2004. Crossref

  12. Yıldız Sibel, Gürgen Ayşenur, Tabbouche Sana, Serdar Gönül, Sökmen Münevver, Kılıç Ali Osman, Comparison of Quorum Sensing Inhibition and Antimicrobial Properties of Some Commercial and Wild Mushrooms Extracted with Supercritical CO2, Celal Bayar Üniversitesi Fen Bilimleri Dergisi, 2019. Crossref

  13. Yamamoto Kyosuke, Nishikawa Yoshihiro, Kimura Takashi, Dombo Munehiko, Matsuura Nariaki, Sugitachi Akio, Antitumor Activities of Low Molecular Weight Fraction Derived from the Cultured Fruit Body of Sparassis crispa in Tumor-Bearing Mice, Nippon Shokuhin Kagaku Kogaku Kaishi, 54, 9, 2007. Crossref

  14. Ohno Naohito, Fungal Polysaccharides, in Comprehensive Glycoscience, 2021. Crossref

  15. Zafar Sadia, Jabeen Farhat, Akram Muhammad, Riaz Zarfishan, Munir Naveed, Mushroom Species and Classification, in Poisonous Plants and Phytochemicals in Drug Discovery, 2020. Crossref

  16. Sharma Neha, Tapwal Ashwani, Verma Rachna, Kumar Dinesh, Nepovimova Eugenie, Kuca Kamil, Medicinal, nutritional, and nutraceutical potential of Sparassis crispa s. lat.: a review, IMA Fungus, 13, 1, 2022. Crossref

  17. Zhang Mei, Lou Ben-Yong, Zhang Yan-Jie, Mei Shu-Jia, Gao Lu-Yao, Chen Wei-Jian, Preparation and characterization of Sparassis latifolia β-glucan microcapsules, Open Chemistry, 20, 1, 2022. Crossref

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