Library Subscription: Guest
International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Gain Access(open in a new tab)
More
Purchase $35.00(open in a new tab) Check subscription Download MARC record(open in a new tab) Get Permissions(open in a new tab)

Vitamins D and D2 in Cultivated Mushrooms under Ultraviolet Irradiation and Their Bioavailability in Humans: A Mini-Review

Volume 23, Issue 11, 2021, pp. 1-15
DOI: 10.1615/IntJMedMushrooms.2021040390
Get accessGet access
Mei Fong Leung
School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
Peter Chi Keung Cheung
Department of Biology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China

ABSTRACT

Vitamin D deficiency is a public health issue that not only results in skeletal disorders but is also linked to several chronic diseases. Several studies have shown that ultraviolet (UV)-treated mushrooms are a potential dietary source of vitamin D, as these mushrooms have a high rate of conversion of ergosterol to vitamin D2. However, there are gaps in knowledge about the most appropriate irradiation conditions, including the source, dose, intensity, and duration of irradiation, for maximizing vitamin D2 content in mushrooms. UVB seems to be most effective in transforming ergosterol to vitamin D2 in both fresh and dried mushrooms. Effects of drying, storage, and thermal treatments on vitamin D content in UV-treated fresh mushrooms have been reported. This knowledge is important for the mushroom industry in order to provide the market with vitamin D2-enhanced mushrooms in a safe and affordable manner. Recent studies in humans focused on the bioavailability of vitamin D2 from mushrooms. The study results showed that UV-treated mushrooms were effective in increasing serum 25-hydroxyvitamin D levels, as they contain high vitamin D2. However, other reports indicate that there are no significant changes in serum 25(OH)D levels and suggest that vitamin D2 is not as effective as vitamin D2 in increasing serum 25(OH) D levels. Vitamin D2 bioavailability is still unclear, and there is an urgent need to investigate the effectiveness, safety, and adequate amount of vitamin D2-enhanced mushrooms for reducing vitamin D deficiency and maintaining vitamin D levels.

KEY WORDS: vitamin D, vitamin D2, cultivated mushrooms, UV irradiation, bioavailability, medicinal mushrooms
REFERENCES

  1. Autier P, Boniol M, Pizot C, Mullie P. Vitamin D status and ill health: A systematic review. Lancet Diabetes Endocrinol. 2014;2(1):76-89.

  2. European Food Safety Authority. Outcome of a public consultation on the draft scientific opinion of the EFSA panel on dietetic products, nutrition, and allergies (NDA) on dietary reference values for vitamin D. EFSA supporting publication 2016:EN-1078. Parma, Italy: EFSA; 2016.

  3. Holick M, Binkley N, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM. Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. J Clin Endocrinol Metab. 2012;97(4):1153-8.

  4. Smith LM, Gallagher JC. Dietary vitamin D intake for the elderly population: Update on the recommended dietary allowance for vitamin D. Endocrinol Metab Clinics North Am. 2017;46(4):871-84.

  5. Tangpricha V. Vitamin D in food and supplements. Am J Clin Nutr. 2012;95(6):1299-300.

  6. Vuolo L, Somma CD, Faggiano A, Colao A. Vitamin D and cancer. Front Endocrinol. 2012;3:58.

  7. Wilson LR, Tripkovic L, Hart KH, Lanham-New SA. Vitamin D deficiency as a public health issue: Using vitamin D2 or vitamin D3 in future fortification strategies. Proc Nutr Soc. 2017;76(3):392-9.

  8. Schmid A, Walther B. Natural vitamin D content in animal products. Adv Nutr. 2013;4(4):453-62.

  9. Kristensen HL, Rosenqvist E, Jakobsen J. Increase of vitamin D(2) by UV-B exposure during the growth phase of white button mushroom (Agaricus bisporus). Food Nutr Res. 2012;56:7114.

  10. Urbain P, Jakobsen J. Dose-response effect of sunlight on vitamin D2 production in Agaricus bisporus mushrooms. J Agric Food Chem. 2015;63(37):8156-61.

  11. Mattila PH. Vitamin D contents in edible mushrooms. J Agric Food Chem. 1994;42(11):2449-53.

  12. Teichmann A, Dutta P, Staffas A, Jagerstad M. Sterol and vitamin D2 concentrations in cultivated and wild grown mushrooms: Effects of UV irradiation. Food Sci Technol. 2007;40(5):815-22.

  13. Slawinska A, Fornal E, Radzki W, Skrzypczak K, Zalewska-Korona M, Michalak-Majewska M, Parfieniuk E. Study on vitamin D2 stability in dried mushrooms during drying and storage. Food Chem. 2016;199:203-9.

  14. Nolle N, Argyropoulos D, Muller J, Biesalski HK. Temperature stability of vitamin D2 and color changes during drying of UVB-treated mushrooms. Drying Technol. 2018;36(3):307-15.

  15. Keflie TS, Nolle N, Lambert C, Nohr D, Biesalski HK. Impact of the natural resource of UVB on the content of vitamin D2 in oyster mushroom (Pleurotus ostreatus) under subtropical settings. Saudi J Biol Sci. 2019;26(7):1724-30.

  16. Wu W-J, Ahn B-Y. Statistical optimization of ultraviolet irradiate conditions for vitamin D2 synthesis in oyster mushrooms (Pleurotus ostreatus) using response surface methodology. PLoS One. 2014;9(4):e95359.

  17. Nolle N, Argyropoulos D, Ambacher S, Muller J. Vitamin D2 enrichment in mushrooms by natural or artificial UV-light during drying. Food Sci Technol. 2017;85:400-4.

  18. Jasinghe VJ, Perera CO. Distribution of ergosterol in different tissues of mushrooms and its effect on the conversion of ergosterol to vitamin D2 by UV irradiation. Food Chem. 2005;92(3):541-6.

  19. Lee NK, Aan B. Optimization of ergosterol to vitamin D2 synthesis in Agaricus bisporus powder using ultraviolet-B radiation. Food Sci Biotechnol. 2016;25(6):1627-31.

  20. Kalaras MD, Beelman RB, Elias RJ. Effects of postharvest pulsed UV light treatment of white button mushrooms (Agaricus bisporus) on vitamin D2 content and quality attributes. J Agric Food Chem. 2012;60(1):220-5.

  21. Roberts JS, Teichert A, McHugh TH. Vitamin D2 formation from post-harvest UV-B treatment of mushrooms (Agaricus bisporus) and retention during storage. J Agric Food Chem. 2008;56(12):4541-4.

  22. Koyyalamudi SR, Jeong S, Song C, Cho KY, Pang G. Vitamin D2 formation and bioavailability from Agaricus bisporus button mushrooms treated with ultraviolet irradiation. J Agric Food Chem. 2009;57(8):3351-5.

  23. Loznjak P, Jakobsen J. Stability of vitamin D3 and vitamin D2 in oil, fish and mushrooms after household cooking. Food Chem. 2018;254:144-9.

  24. Keegan RH, Lu Z, Bogusz JM, Williams JE, Holick MF. Photobiology of vitamin D in mushrooms and its bioavailability in humans. Dermatoendocrinology. 2014;5(1):165-76.

  25. Mehrotra A, Calvo MS, Beelman RB, Levy E, Siuty J, Kalaras MD, Uribarri J. Bioavailability of vitamin D2 from enriched mushrooms in prediabetic adults: A randomized controlled trial. Eur J Clin Nutr. 2014:68(10):1154-60.

  26. Nieman DC, Gillitt ND, Shanely RA, Dew D, Meaney MP, Luo B. Vitamin D2 supplementation amplifies eccentric exercise-induced muscle damage in NASCAR pit crew athletes. Nutrients. 2013;6(1):63-75.

  27. Shanely RA, Nieman DC, Knab AM, Gillitt ND, Meaney MP, Jin F, Sha W, Cialdella-Kam L. Influence of vitamin D mushroom powder supplementation on exercise-induced muscle damage in vitamin D insufficient high school athletes. J Sports Sci. 2014;32(7):670-9.

  28. Stephensen CB, Zerofsky M, Burnett DJ, Lin Y, Hammock BD, Hall LM, McHugh T. Ergocalciferol from mushrooms or supplements consumed with a standard meal increases 25-hydroxyergocalciferol but decreases 25-hydroxycholecalciferol in the serum of healthy adults. J Nutr. 2012;142(7):1246-52.

  29. Stepien M, O'Mahony L, O'Sullivan A, Collier J, Fraser WD, Gibney MJ, Nugent AP, Brennan L. Effect of supplementation with vitamin D2-enhanced mushrooms on vitamin D status in healthy adults. J Nutr Sci. 2013;2:e29.

  30. Urbain P, Singler F, Ihorst G, Biesalski H-K, Bertz H. Bioavailability of vitamin D2 from UV-B-irradiated button mushrooms in healthy adults deficient in serum 25-hydroxyvitamin D: A randomized controlled trial. Eur J Clin Nutr. 2011;65(8):965-71.

  31. Cashman, KD, Kiely M, Seamans KM, Urbain P. Effect of ultraviolet light-exposed mushrooms on vitamin D status: Liquid chromatography-tandem mass spectrometry reanalysis of biobanked sera from a randomized controlled trial and a systematic review plus meta-analysis. J Nutr. 2016;146(3):565-75.

  32. Houghton LA, Vieth R. The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin Nutr. 2006;84(4):694-7.

  33. Guan W, Zhang J, Yan R, Shao S, Zhou T, Lei J, Wang Z. Effects of UV-C treatment and cold storage on ergosterol and vitamin D2 contents in different parts of white and brown mushroom (Agaricus bisporus). Food Chem. 2016;210:129-34.

CITED BY

  1. Liang Qishun, Chen Tianyu, Luo Lvqi, Ma Yizhe, Wen Congcong, Huang Xueli, Pharmacokinetics and bioavailability of curdione in mice by UPLC-MS/MS, Acta Chromatographica, 2022. Crossref

  2. Koeder Christian, Perez-Cueto Federico J. A., Vegan nutrition: a preliminary guide for health professionals, Critical Reviews in Food Science and Nutrition, 2022. Crossref

11622 Article views 34 Article downloads Metrics
11622 VIEWS 34 DOWNLOADS 2 Crossref CITATIONS Google
Scholar CITATIONS

Articles with similar content:

Vitamin D and Vitamin D from Ultraviolet-Irradiated Mushrooms (Review) International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 3
Paul Kuria Kamweru , Edward L Tindibale
The Protective Effects of Aqueous Extracts of Wild-Growing and Fermented Royal Sun Mushroom, Agaricus brasiliensis S. Wasser et al. (Higher Basidiomycetes), in CCl4-Induced Oxidative Damage in Rats International Journal of Medicinal Mushrooms, Vol.14, 2012, issue 6
Haitao Yu, Baosheng Zhao, Chunchao Han, Chun-Jing Zhang
Vitamin D2 Stability During the Refrigerated Storage of Ultraviolet B−Treated Cultivated Culinary-Medicinal Mushrooms International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 3
Ewa Jablonska-Rys, Emilia Fornal, Ewa Parfieniuk, Wojciech Radzki, Aneta Slawinska
Culinary-Medicinal Mushroom Products as a Potential Source of Vitamin D International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 10
Grażyna Jaworska, Emilia Bernas
The Hepatoprotective Effect of Clidemia hirta against Carbon Tetrachloride (CCl4)−Induced Oxidative Stress and Hepatic Damage in Mice Journal of Environmental Pathology, Toxicology and Oncology, Vol.36, 2017, issue 4
Mohammad Iqbal, Nurul Amzar

Latest Issue

Anti-Hyperglycemic Effect of the Brown Slime Cap Mushroom Chroogomphus rutilus (Agaricomycetes) Crude Polysaccharide In Vitro and In Vivo Lichao Guo, Qingguo Yao, Jianhua Lv, Zhuang Li, Li-An Wang, Jinxiu Zhang

Forthcoming Articles

Exploring the Functional Properties and Nutritional Values of Coloured Oyster Mushrooms Species of Genus Pleurotus (Agaricomycetes): A Review Nurul Izzati Medihi, Zaibunnisa Abdul Haiyee, Patmawati Patmawati, Sukor Rashidah, Raseetha Siva Influence of Drying Temperatures on Colour Variation, Phenolic Compounds and Multi-Elemental Composition of Some Culinary- Medicinal Mushrooms Nur-Amirah Izzah Nasarudin, Azilah Abdul-Malek , Nurulain Syuhada Mohamad Yazid, Sukor Rashidah, Jegadeesh Raman, Raseetha Siva Anti-hyperuricaemic Activity and Potential Mechanisms of Mushrooms: A Review of Preclinical Studies Chun-Hong Lai, Hui-Chen Lo Taxonomic Identification and Nutritional Profiling of Wild Isolates of the Pink Oyster Mushroom Pleurotus djamor (Agaricomycetes) from Northwestern Himalayas (India) Shikha Guleria Chemical composition and antimicrobial properties of Morchella crassipes from Kashmir Valley, India MEHRAJUDDIN TALIE, John Mohd War, Anees Un Nisa, Asif Hamid Dar, Abdul Hamid Wani, Mohd Yaqub Bhat Effects of Outdoor Grown the Royal Sun Medicinal Mushroom Agaricus brasiliensis KA21 (Agaricomycetes) Fruit Body on Canine Malassezia Dermatitis Akitomo Motoi, Katsuya Tajima, Masuro Motoi, Katsuaki Nishihara, Daisuke Yamanaka, Ken-ichi Ishibashi, Naohito Ohno, Yoshiyuki Adachi
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections Prices and Subscription Policies Begell House Contact Us Language English 中文 Русский Português German French Spain