年間 6 号発行
ISSN 印刷: 1040-8401
ISSN オンライン: 2162-6472
Indexed in
Signal Transduction via MHC Class I Molecules in Endothelial and Smooth Muscle Cells
要約
MHC class I molecules have long been recognized for their ability to stimulate intracellular signals in T and B lymphocytes. More recently, it has become clear that MHC class I molecules can also initiate intracellular signals in endothelial and smooth muscle cells, which synergize with growth factor receptors to elicit cell proliferation. This review describes our current knowledge of class I–mediated signaling pathways in human endothelial and smooth muscle cells. The role of the class I signaling pathway in modulating cell growth and the clinical significance of this pathway in chronic allograft rejection are discussed.
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Smith R. N., Kawai T., Boskovic S., Nadazdin O., Sachs D. H., Cosimi A. B., Colvin R. B., Chronic Antibody Mediated Rejection of Renal Allografts: Pathological, Serological and Immunologic Features in Nonhuman Primates, American Journal of Transplantation, 6, 8, 2006. Crossref
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Charron Dominique, Suberbielle-Boissel Caroline, Al-Daccak Reem, Immunogenicity and Allogenicity: A Challenge of Stem Cell Therapy, Journal of Cardiovascular Translational Research, 2, 1, 2009. Crossref
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Soleimani B., Lechler R. I., Hornick P. I., George A. J. T., Role of Alloantibodies in the Pathogenesis of Graft Arteriosclerosis in Cardiac Transplantation, American Journal of Transplantation, 6, 8, 2006. Crossref
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Jin Yi-Ping, Jindra Peter T., Gong Ke Wei, Lepin Eric J., Reed Elaine F., Anti-HLA Class I Antibodies Activate Endothelial Cells and Promote Chronic Rejection, Transplantation, 79, Supplement, 2005. Crossref
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Zhang Qiuheng, Liang Leonard W., Gjertson David W., Lassman Charles, Wilkinson Alan H., Kendrick Elizabeth, Pham Phuong-Thu T., Danovitch Gabriel M., Gritsch H Albin, Reed Elaine F., Development of Posttransplant Antidonor HLA Antibodies Is Associated with Acute Humoral Rejection and Early Graft Dysfunction, Transplantation, 79, 5, 2005. Crossref
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Lepin Eric J., Reed Elaine F., Complement-independent mechanisms of antigraft antibodies in transplant arteriosclerosis and accommodation, Current Opinion in Organ Transplantation, 9, 1, 2004. Crossref
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Jindra Peter T., Zhang Xiaohai, Mulder Arend, Claas Frans, Veale Jeffrey, Jin Yi-Ping, Reed Elaine F., Anti-HLA Antibodies Can Induce Endothelial Cell Survival or Proliferation Depending on their Concentration, Transplantation, 82, Supplement 1, 2006. Crossref
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Jindra Peter T, Reed Elaine F, Signal transduction through major histocompatibility complex molecules, Current Opinion in Organ Transplantation, 12, 4, 2007. Crossref
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Zachary A. A., Montgomery R. A., Jordan S. C., Reinsmoen N. L., Claas F. H. J., Reed E. F., 14th International HLA and Immunogenetics Workshop: Report on understanding antibodies in transplantation, Tissue Antigens, 69, 2007. Crossref
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Kobashigawa Jon, Mehra Mandeep, West Lori, Kerman Ronald, George James, Rose Marlene, Zeevi Adriana, Reinsmoen Nancy, Patel Jignesh, Reed Elaine F., Report From a Consensus Conference on the Sensitized Patient Awaiting Heart Transplantation, The Journal of Heart and Lung Transplantation, 28, 3, 2009. Crossref
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Colovai Adriana I., Vasilescu Elena R., Foca-Rodi Aurica, Kim-Schulze Seunghee, Hussaini Najeeb, D’agati Vivette D., Markowitz Glen S., Wang Chuan, Cohen David J., Hardy Mark A., Suciu-Foca Nicole, Acute and Hyperacute Humoral Rejection in Kidney Allograft Recipients Treated with Anti-Human Thymocyte Antibodies, Human Immunology, 66, 5, 2005. Crossref
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Cecka J. Michael, Zhang Qiuheng, Reed Elaine F., Preformed Cytotoxic Antibodies in Potential Allograft Recipients: Recent Data, Human Immunology, 66, 4, 2005. Crossref
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Peng Alice, Vo Ashley, Jordan Stanley C., Transplantation of the highly human leukocyte antigen–sensitized patient: long-term outcomes and future directions, Transplantation Reviews, 20, 3, 2006. Crossref
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Morales-Buenrostro L.E., Buzo-Romero J.M., de Leo C., López M., Ortiz-Arroyo V.M., Pérez-Garrido J., Herrera-Garcia C., Granados J., Alberú J., Prevalence of HLA Antibodies and Its Impact on Graft Function in a Group of Kidney Transplant Recipients: A Cross-Sectional Study, Transplantation Proceedings, 38, 3, 2006. Crossref
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Jin Y.-P., Valenzuela N. M., Ziegler M. E., Rozengurt E., Reed E. F., Everolimus Inhibits Anti-HLA I Antibody-Mediated Endothelial Cell Signaling, Migration and Proliferation More Potently Than Sirolimus, American Journal of Transplantation, 14, 4, 2014. Crossref
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Moody Paul R, Sayers Edward J, Magnusson Johannes P, Alexander Cameron, Borri Paola, Watson Peter, Jones Arwyn T, Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes, Molecular Therapy, 23, 12, 2015. Crossref
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Parkes Michael D., Halloran Philip F., Hidalgo Luis G., Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection, Transplantation, 101, 4, 2017. Crossref
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Xia Simo, Tao Yijie, Cui Likun, Yu Yizhi, Xu Sheng, MHC Class I Molecules Exacerbate Viral Infection by Disrupting Type I Interferon Signaling, Journal of Immunology Research, 2019, 2019. Crossref
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Jindra Peter T., Hsueh Aileen, Hong Longshen, Gjertson David, Shen Xiu-Da, Gao Feng, Dang Julie, Mischel Paul S., Baldwin William M., Fishbein Michael C., Kupiec-Weglinski Jerzy W., Reed Elaine F., Anti-MHC Class I Antibody Activation of Proliferation and Survival Signaling in Murine Cardiac Allografts, The Journal of Immunology, 180, 4, 2008. Crossref
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Jindra Peter T., Jin Yi-Ping, Rozengurt Enquire, Reed Elaine F., HLA Class I Antibody-Mediated Endothelial Cell Proliferation via the mTOR Pathway, The Journal of Immunology, 180, 4, 2008. Crossref
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Zeevi Adriana, Lunz John G., Human leukocyte antigen antibodies in liver retransplantation, Liver Transplantation, 16, 3, 2010. Crossref
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Zhang Zhengrong, Na Hana, Gan Qini, Tao Qiushan, Alekseyev Yuriy, Hu Junming, Yan Zili, Yang Jack B., Tian Hua, Zhu Shenyu, Li Qiang, Rajab Ibraheem M., Blusztajn Jan Krizysztof, Wolozin Benjamin, Emili Andrew, Zhang Xiaoling, Stein Thor, Potempa Lawrence A., Qiu Wei Qiao, Monomeric C‐reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype‐dependent pattern: A risk factor for Alzheimer’s disease?, Aging Cell, 20, 11, 2021. Crossref
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Galvani Sylvain, Trayssac Magali, Augé Nathalie, Thiers Jean-Claude, Calise Denis, Krell Hans-Willi, Sallusto Federico, Kamar Nassim, Rostaing Lionel, Thomsen Mogens, Nègre-Salvayre Anne, Salvayre Robert, A Key Role for Matrix Metalloproteinases and Neutral Sphingomyelinase-2 in Transplant Vasculopathy Triggered by Anti-HLA Antibody, Circulation, 124, 24, 2011. Crossref
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Cheung Kenneth C. P., Fanti Silvia, Mauro Claudio, Wang Guosu, Nair Anitha S., Fu Hongmei, Angeletti Silvia, Spoto Silvia, Fogolari Marta, Romano Francesco, Aksentijevic Dunja, Liu Weiwei, Li Baiying, Cheng Lixin, Jiang Liwen, Vuononvirta Juho, Poobalasingam Thanushiyan R., Smith David M., Ciccozzi Massimo, Solito Egle, Marelli-Berg Federica M., Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming, Nature Communications, 11, 1, 2020. Crossref