年間 6 号発行
ISSN 印刷: 0743-4863
ISSN オンライン: 2162-660X
Indexed in
Therapy Considerations in Drug-Eluting Stents
要約
Approximately 12 million Americans have coronary artery disease, and almost one in five deaths in the United States can be attributed to this disease. In addition, 1.2 million Americans undergo cardiac catheterization and over one-half million receive a percutaneous coronary intervention such as balloon angioplasty, atherectomy, or stent implantation annually. This article will provide an overview of (1) atherosclerosis, the progressive disease which can lead to thrombotic events and/or the development of hemodynamically significant coronary artery lesions; (2) restenosis, the reappearance of significant lesions after coronary interventions such as stent placement; and (3) drugeluting stents, the devices which, by using appropriate polymers to elute the appropriate drug with the appropriate pharmacokinetics, have almost completely eliminated restenosis.
-
Hossainy Syed, Prabhu Santosh, A mathematical model for predicting drug release from a biodurable drug-eluting stent coating, Journal of Biomedical Materials Research Part A, 87A, 2, 2008. Crossref
-
Calo V. M., Brasher N. F., Bazilevs Y., Hughes T. J. R., Multiphysics model for blood flow and drug transport with application to patient-specific coronary artery flow, Computational Mechanics, 43, 1, 2008. Crossref
-
Prabhu Santosh, Hossainy Syed, Modeling of degradation and drug release from a biodegradable stent coating, Journal of Biomedical Materials Research Part A, 80A, 3, 2007. Crossref
-
Mahoney Christine M., Patwardhan Dinesh V., Ken McDermott M., Characterization of drug-eluting stent (DES) materials with cluster secondary ion mass spectrometry (SIMS), Applied Surface Science, 252, 19, 2006. Crossref
-
Venkatraman Subbu, Boey Freddy, Release profiles in drug-eluting stents: Issues and uncertainties, Journal of Controlled Release, 120, 3, 2007. Crossref
-
Pan Chang-Jiang, Tang Jia-Ju, Weng Ya-Jun, Wang Jin, Huang Nan, Preparation and in vitro release profiles of drug-eluting controlled biodegradable polymer coating stents, Colloids and Surfaces B: Biointerfaces, 73, 2, 2009. Crossref
-
Trollsas Mikael, Maslanka Bozena, Pham Nam, Lin Qing, Hossainy Syed, Hsu Shaw Ling, Ngo Michael Huy, Polyesteramide Coatings for Drug Eluting Stents: Controlling Drug Release by Polymer Engineering, in Active Implants and Scaffolds for Tissue Regeneration, 8, 2011. Crossref
-
dos Santos Leandro F., de Carvalho Júlio C., Rubel Rosália, Soccol Carlos Ricardo, Microbial Statins, in Biotransformation of Waste Biomass into High Value Biochemicals, 2014. Crossref