年間 6 号発行
ISSN 印刷: 0743-4863
ISSN オンライン: 2162-660X
Indexed in
Drug Delivery Systems for the Treatment of Restenosis
要約
Attempts to achieve revascularization of coronary arteries blocked by atherosclerotic plaques are hampered by restenotic hyperproliferative response of die treated vessels. The uniform failure of clinical trials using systemic therapies to prevent restenosis has prompted development of methods for arterial drug delivery systems. This review describes technologies of polymeric-based, perivascular, and intraluminal drug and gene delivery systems. The critical assessment of controversies including drug and vehicle type, dose and release rate, and preclinical validation is reviewed.
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Cohen-Sela Einat, Elazar Victoria, Epstein-Barash Hila, Golomb Gershon, Nano-Carriers of Drugs and Genes for the Treatment of Restenosis, in Nanoparticulate Drug Delivery Systems, 20075578, 2007. Crossref
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Sharkawi Tahmer, Cornhill Frederick, Lafont Antoine, Sabaria Patrick, Vert Michel, Intravascular bioresorbable polymeric stents: A potential alternative to current drug eluting metal stents, Journal of Pharmaceutical Sciences, 96, 11, 2007. Crossref
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Feng Si-Shen, Nanoparticles of biodegradable polymers for new-concept chemotherapy, Expert Review of Medical Devices, 1, 1, 2004. Crossref
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Huang Guofeng, Zhou Zhongmin, Srinivasan Rekha, Penn Marc S., Kottke-Marchant Kandice, Marchant Roger E., Gupta Anirban S., Affinity manipulation of surface-conjugated RGD peptide to modulate binding of liposomes to activated platelets, Biomaterials, 29, 11, 2008. Crossref
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Chorny Michael, Fishbein Ilia, Danenberg Haim D, Golomb Gershon, Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics, Journal of Controlled Release, 83, 3, 2002. Crossref
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Cohen-Sacks Hagit, Elazar Victoria, Gao Jianchuan, Golomb Assaf, Adwan Hassan, Korchov Nikoly, Levy Robert J, Berger Martin R, Golomb Gershon, Delivery and expression of pDNA embedded in collagen matrices, Journal of Controlled Release, 95, 2, 2004. Crossref
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Bohl Masters Kristyn S., Lipke Elizabeth A., Rice Elizabeth E. H., Liel Meghan S., Myler Heather A., Zygourakis Corinna, Tulis David A., West Jennifer L., Nitric oxide-generating hydrogels inhibit neointima formation, Journal of Biomaterials Science, Polymer Edition, 16, 5, 2005. Crossref
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Westedt Ulrich, Kalinowski Marc, Wittmar Matthias, Merdan Thomas, Unger Florian, Fuchs Jutta, Schäller Susann, Bakowsky Udo, Kissel Thomas, Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment, Journal of Controlled Release, 119, 1, 2007. Crossref
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Zweers Miechel L.T., Engbers Gerard H.M., Grijpma Dirk W., Feijen Jan, Release of anti-restenosis drugs from poly(ethylene oxide)-poly(dl-lactic-co-glycolic acid) nanoparticles, Journal of Controlled Release, 114, 3, 2006. Crossref
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Epstein Hila, Afergan Eyal, Koroukhov Nickolay, Eisenberg Galit, Gutman Dikla, Golomb Gershon, Liposomal Bisphosphonates for the Treatment of Restenosis, in Liposome Technology, Volume II, 2006. Crossref
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Shi Xudong, Chen Guojun, Guo Lian-Wang, Si Yi, Zhu Men, Pilla Srikanth, Liu Bo, Gong Shaoqin, Kent K. Craig, He Xiaoming, Periadventitial Application of Rapamycin-Loaded Nanoparticles Produces Sustained Inhibition of Vascular Restenosis, PLoS ONE, 9, 2, 2014. Crossref
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Varshosaz J., Soheili M., Production andin vitrocharacterization of lisinopril-loaded nanoparticles for the treatment of restenosis in stented coronary arteries, Journal of Microencapsulation, 25, 7, 2008. Crossref
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Sarısözen Can, Arıca Betül, Orman Mehmet N., Hıncal A. Atilla, Çalış Sema, Optimization of prednisolone acetate-loaded chitosan microspheres using a 23factorial design for preventing restenosis, Drug Delivery, 17, 3, 2010. Crossref
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Sarısözen Can, Arıca Betül, Hıncal A. Atilla, Çalış Sema, Development of biodegradable drug releasing polymeric cardiovascular stents andin vitroevaluation, Journal of Microencapsulation, 26, 6, 2009. Crossref
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Sachar Ravish, Topol Eric J., Local Gene and Cell Delivery Devices, in Essentials of Restenosis, 2007. Crossref
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Epstein Hila , Rabinovich Laura, Banai Shmuel, Elazar Vicktoria, Gao Jianchuan, Chorny Michael, Danenebrg Haim D, Golomb Gershon, Predicting In Vivo Efficacy of Potential Restenosis Therapies by Cell Culture Studies: Species-Dependent Susceptibility of Vascular Smooth Muscle Cells, The Open Cardiovascular Medicine Journal, 2, 1, 2008. Crossref
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Fishbein Ilia, Chorny Michael, Alferiev Ivan S., Levy Robert J., Site Specific Controlled Release for Cardiovascular Disease: Translational Directions, in Fundamentals and Applications of Controlled Release Drug Delivery, 2012. Crossref
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Aizik Gil, Waiskopf Nir, Agbaria Majd, Ben-David-Naim Meital, Nordling-David Mirjam M., Jbara-Agbaria Doaa, Banin Uri, Golomb Gershon, Targeting and imaging of monocyte-derived macrophages in rat's injured artery following local delivery of liposomal quantum dots, Journal of Controlled Release, 318, 2020. Crossref
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Zilberman Meital, Kraitzer Amir, Grinberg Orly, Elsner Jonathan J., Drug-Eluting Medical Implants, in Drug Delivery, 197, 2010. Crossref
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Fishbein Ilia, Chorny Michael, Golomb Gershon, Treatment of restenosis by controlled‐release delivery systems of tyrphostins, Drug Development Research, 50, 3-4, 2000. Crossref
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Cohen-Sacks H, Najajreh Y, Tchaikovski V, Gao G, Elazer V, Dahan R, Gati I, Kanaan M, Waltenberger J, Golomb G, Novel PDGFβR antisense encapsulated in polymeric nanospheres for the treatment of restenosis, Gene Therapy, 9, 23, 2002. Crossref