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Critical Reviews™ in Immunology

Publicou 6 edições por ano

ISSN Imprimir: 1040-8401

ISSN On-line: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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Mechanisms of Induction of Tolerance to Organ Allografts

Volume 20, Edição 4, 2000, 58 pages
DOI: 10.1615/CritRevImmunol.v20.i4.10
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RESUMO

The long-term acceptance of organ allografts can be induced in numerous rodent and some preclinical outbred models. Induction methods can use donor alloantigen in various forms, including spontaneous acceptance of grafts such as livers, to deviate the immune response so a subsequent graft will be accepted. Establishment of lymphohemopoietic chimerism is not essential. Short-term immunosuppressive treatments that prevent acute rejection can also induce tolerance. These include nonspecific immunosuppressive drugs and immunotherapy that blocks cell surface molecular interactions or cytokine function. There is variation in the effect of these protocols on different strain combinations that may be due to innate differences in the cell sub-populations and cytokines activated in the hosts. Th1 cytokines, although important in the mediation of rejection, are also required for induction of tolerance. Th2 cytokines may facilitate tolerance induction but are not essential. The tolerant state takes weeks to fully mature after exposure to alloantigen. Tolerance is associated with a loss or change in dendritic cells and the development of suppressor cells, which in all cases include CD4+ T cells. In the near future precise understanding of the function of these two cell types may allow diagnosis and induction of tolerance in clinical transplantation.

CITADO POR
  1. Hall Bruce M., Plain Karren M., Verma Nirupama D., Tran Giang T., Boyd Rochelle, Robinson Catherine M., Nicolls Mark R., Berger Manuela E., Nomura Masaru, Hodgkinson Suzanne J., Transfer of Allograft Specific Tolerance Requires CD4+CD25+T Cells but Not Interleukin-4 or Transforming Growth Factor–β and Cannot Induce Tolerance to Linked Antigens, Transplantation, 83, 8, 2007. Crossref

  2. Asolati Massimo, Testa Giuliano, Gangemi Antonio, Sankary Howard, Oberholzer Jos??, Benedetti Enrico, ???Prope??? Tolerance in a Noncompliant Living Related Small Bowel Transplant Recipient After Severe Rejection, Transplantation, 83, 1, 2007. Crossref

  3. Plain Karren M., Verma Nirupama D., Tran Giang T., Nomura Masaru, Boyd Rochelle, Robinson Catherine M., Hodgkinson Suzanne J., Hall Bruce M., Cytokines affecting CD4+ T regulatory cells in transplant tolerance. Interleukin-4 does not maintain alloantigen specific CD4+CD25+ Treg, Transplant Immunology, 29, 1-4, 2013. Crossref

  4. Plain Karren M., Boyd Rochelle, Verma Nirupama D., Robinson Catherine M., Tran Giang T., Hodgkinson Suzanne J., Hall Bruce M., Transplant Tolerance Associated With a Th1 Response and Not Broken by IL-4, IL-5, and TGF-β Blockade or Th1 Cytokine Administration, Transplantation, 83, 6, 2007. Crossref

  5. Waldmann H, Therapeutic aspects of tolerance, Current Opinion in Pharmacology, 1, 4, 2001. Crossref

  6. Bridle Byram W., Wilkie Bruce N., Jevnikar Anthony M., Mallard Bonnie A., Deviation of xenogeneic immune response and bystander suppression in rats fed porcine blood mononuclear cells, Transplant Immunology, 17, 4, 2007. Crossref

  7. Waldmann Herman, Therapeutic approaches for transplantation, Current Opinion in Immunology, 13, 5, 2001. Crossref

  8. Mellergård Johan, Havarinasab Said, Hultman Per, Short- and long-term effects of T-cell modulating agents in experimental autoimmunity, Toxicology, 196, 3, 2004. Crossref

  9. Garin Marina I., Lechler Robert I., Regulatory T cells, Current Opinion in Organ Transplantation, 8, 1, 2003. Crossref

  10. Waldmann Herman, Cobbold Stephen, Regulating the Immune Response to Transplants, Immunity, 14, 4, 2001. Crossref

  11. Yoshida A., Narumi S., Hashimoto N., Itabashi Y., Hakamada K., Sasaki M., CD8 T cell of donor splenocyte mixed with bone marrow cells is more effective than CD4 T cell for induction of donor-specific tolerance in sublethally irradiated mice, Transplantation Proceedings, 36, 8, 2004. Crossref

  12. Hall Bruce M., Tran Giang, Hodgkinson Suzanne J., Alloantigen specific T regulatory cells in transplant tolerance, International Immunopharmacology, 9, 5, 2009. Crossref

  13. Hall Bruce M., CD4+CD25+ T Regulatory Cells in Transplantation Tolerance, Transplantation, 100, 12, 2016. Crossref

  14. McCaughan G, Withdrawal of immunosuppression in liver transplant recipients: Is this as good as it gets?, Liver Transplantation, 8, 4, 2002. Crossref

  15. Hall Bruce M., Plain Karren M., Tran Giang T., Verma Nirupama D., Robinson Catherine M., Nomura Masaru, Boyd Rochelle, Hodgkinson Suzanne J., Cytokines affecting CD4 + T regulatory cells in transplant tolerance. III. Interleukin-5 (IL-5) promotes survival of alloantigen-specific CD4 + T regulatory cells, Transplant Immunology, 43-44, 2017. Crossref

  16. Nomura Masaru, Hodgkinson Suzanne J., Tran Giang T., Verma Nirupama D., Robinson Catherine, Plain Karren M., Boyd Rochelle, Hall Bruce M., Cytokines affecting CD4 + T regulatory cells in transplant tolerance. II. Interferon gamma (IFN-γ) promotes survival of alloantigen-specific CD4 + T regulatory cells, Transplant Immunology, 42, 2017. Crossref

  17. Bishop G. Alex, McCaughan Geoffrey W., Immune activation is required for the induction of liver allograft tolerance: Implications for immunosuppressive therapy, Liver Transplantation, 7, 3, 2001. Crossref

  18. Tung Thomas H. H., Mackinnon Susan E., Mohanakumar T., Long-term limb allograft survival using anti-CD40L antibody in a murine model, Transplantation, 75, 5, 2003. Crossref

  19. Yan Yiqun, van der Putten Karien, Bowen David G., Painter Dorothy M., Kohar Jimmy, Sharland Alexandra F., McCaughan Geoffrey W., Bishop G. Alex, Postoperative administration of donor B cells induces rat kidney allograft acceptance: lack of association with TH2 cytokine expression in long-term accepted grafts1, Transplantation, 73, 7, 2002. Crossref

  20. Lechler Robert I., Garden Oliver A., Turka Laurence A., The complementary roles of deletion and regulation in transplantation tolerance, Nature Reviews Immunology, 3, 2, 2003. Crossref

  21. Waldmann Herman, Reprogramming the immune system, Immunological Reviews, 185, 1, 2002. Crossref

  22. Chandraker Anil, Sayegh Mohamed H., Transplantation Immunology, in Immunology, Infection, and Immunity, 2015. Crossref

  23. Hall Bruce M., Verma Nirupama D., Tran Giang T., Hodgkinson Suzanne J., Transplant Tolerance, Not Only Clonal Deletion, Frontiers in Immunology, 13, 2022. Crossref

  24. Watson Debbie, Zhang Geoff Yu, Sartor Mary, Alexander Stephen I., “Pruning” of Alloreactive CD4+ T Cells Using 5- (and 6-)Carboxyfluorescein Diacetate Succinimidyl Ester Prolongs Skin Allograft Survival, The Journal of Immunology, 173, 11, 2004. Crossref

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