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Critical Reviews™ in Therapeutic Drug Carrier Systems

Publicou 6 edições por ano

ISSN Imprimir: 0743-4863

ISSN On-line: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

Indexed in

Advanced Implantable Drug Delivery Systems via Continuous Manufacturing

Volume 33, Edição 6, 2016, pp. 569-589
DOI: 10.1615/CritRevTherDrugCarrierSyst.2016018537
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RESUMO

Polymeric implantable drug delivery systems have remarkable potential for systemic delivery of various therapeutic agents. Generally, drug-loaded implants do not require a vehicle for delivery and can be used to attain prolonged delivery into the systemic circulation of active pharmaceutical ingredients (APIs) with enhanced drug bioavailability. Furthermore, implants can provide drug release ranging from months to years, which improves patient compliance, especially for poorly bioavailable and rapidly metabolized compounds. Continuous manufacturing technology (e.g., hot-melt extrusion, or HME) has been successfully employed to prepare drug-loaded single-unit polymeric implants. Employing heat and mechanical shear, such systems retain the stability of thermolabile therapeutics (e.g., proteins) in implants. HME has emerged as important because of its varied applications that combine economic viability with solvent-free and easy scale-up processing. Moreover, it has been recognized from a quality-by-design (QbD) viewpoint by the FDA.

CITADO POR
  1. Rust Brett, Tsaponina Olga, Maniruzzaman Mohammed, Recent Innovations in Additive Manufacturing Across Industries: 3D Printed Products and FDA's Perspectives, in 3D and 4D Printing in Biomedical Applications, 2018. Crossref

  2. Shi Nian-Qiu, Wang Shu-Ran, Zhang Yong, Huo Jun-Shuang, Wang Li-Na, Cai Jian-Hui, Li Zheng-Qiang, Xiang Bai, Qi Xian-Rong, Hot melt extrusion technology for improved dissolution, solubility and “spring-parachute” processes of amorphous self-micellizing solid dispersions containing BCS II drugs indomethacin and fenofibrate: Profiles and mechanisms, European Journal of Pharmaceutical Sciences, 130, 2019. Crossref

  3. Tambe Srushti, Jain Divya, Agarwal Yashvi, Amin Purnima, Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications, Journal of Drug Delivery Science and Technology, 63, 2021. Crossref

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