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Critical Reviews™ in Eukaryotic Gene Expression

Publicou 6 edições por ano

ISSN Imprimir: 1045-4403

ISSN On-line: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Muscle-Based Gene Therapy and Tissue Engineering

Volume 11, Edição 1-3, 2001, 10 pages
DOI: 10.1615/CritRevEukarGeneExpr.v11.i1-3.60
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RESUMO

The development of new biological approaches based on cell and gene therapies, in combination with tissue engineering, may create innovative ways to treat various tissues of the musculoskeletal system. It is vital for practicing orthopaedic surgeons to understand the terminology, fundamental concepts, and current research in this burgeoning field so that they may practice their discipline in its fullest form. Such techniques, coupled with advances in cell biology and polymer chemistry, are resulting in novel approaches to treating musculoskeletal disorders in which surgeons, who have traditionally used the tools of excision and reconstruction to treat patients, may now serve as surgical gardeners who create microenvironments that are conducive for tissue regeneration. Gene therapy and tissue engineering applications for bone healing, articular disorders, and skeletal muscle diseases and injuries are currently being explored. This review is intended to update readers on the principles and current advances in muscle-based gene therapy and tissue engineering for the musculoskeletal system.

CITADO POR
  1. Umehara Kohsuke, Iimura Tadahiro, Sakamoto Kei, Lin Zayar, Kasugai Shohei, Igarashi Yoshimasa, Yamaguchi Akira, Canine Oral Mucosal Fibroblasts Differentiate into Osteoblastic Cells in Response to BMP-2, The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 295, 8, 2012. Crossref

  2. Garcia A.J., Guldberg R.E., Byers B.A., Gersbach C.A., Phillips J.E., Addressing cell-sourcing limitations with gene therapy, IEEE Engineering in Medicine and Biology Magazine, 22, 5, 2003. Crossref

  3. Badylak Stephen F., Extracellular matrix as a scaffold for tissue engineering in veterinary medicine: Applications to soft tissue healing, Clinical Techniques in Equine Practice, 3, 2, 2004. Crossref

  4. O'Rourke J.P, Hiraragi H, Urban K, Patel M, Olsen J.C, Bunnell B.A, Analysis of gene transfer and expression in skeletal muscle using enhanced EIAV lentivirus vectors, Molecular Therapy, 7, 5, 2003. Crossref

  5. Young Brett H., Peng Hairong, Huard Johnny, Muscle-Based Gene Therapy and Tissue Engineering to Improve Bone Healing, Clinical Orthopaedics and Related Research, 403, 2002. Crossref

  6. Hirata K, Tsukazaki T, Kadowaki A, Furukawa K, Shibata Y, Moriishi T, Okubo Y, Bessho K, Komori T, Mizuno A, Yamaguchi A, Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2, Bone, 32, 5, 2003. Crossref

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