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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Medicinal Polypores of the Forests of North America: Screening for Novel Antiviral Activity

Volume 7, Edição 3, 2005, 362 pages
DOI: 10.1615/IntJMedMushrooms.v7.i3.210
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RESUMO

Polypore mushrooms have been used medicinally for thousands of years. The Greek physician Dioscorides first described the use of a wood conk, Agarikon, now known as Fomitopsis officinalis (Vill.: Fr.) Bond. et Singer (= Laricifomes officinalis), as a treatment against consumption in 65 AD. Other wood conks, such as Ling Chi or Reishi, have had a similarly long history of use in Asia. In the past 20 years, wood conks have been carefully explored for their immunomodulating and anticancer properties. More recently, mushrooms, including polypores, have and are being explored for their antimicrobial properties.
Upon submitting more than a hundred in vitro cultures of mushrooms to the US Defense Department’s Bioshield BioDefense program, several tests show that some of these polypore mushrooms have strong antiviral activity. Within these verdant natural landscapes, trees hundreds of years old host ancestral strains of these elusive polypores. Species that are now rare, or in some cases thought to be extinct, still reside in the pristine old growth forests of the Pacific Northwest of North America. When clones from these mushrooms were grown in vitro and submitted for antiviral screening, several mycelial cultures produced antibiotics effective against Pox and other viruses. Notably, strains vary in their antiviral properties. Our natural genomes hold within them great potentials for staving off disease and have not yet been fully explored. The fungal diversity within these genomes may prove critical for isolating the most active strains, similar to the lessons learned from the isolation of Penicillium chrysogenum strains that lead to the commercialization of penicillin and saved millions of lives.
With deforestation, pollution, and industrialization, societies should reevaluate the importance of their natural forests in the context that they hold within them novel medicines of enormous socio-economic importance. The old paradigm of viewing the forest as valuable only in terms of timber seems overly simplistic given this new knowledge.

CITADO POR
  1. Gilhen-Baker Melinda, Roviello Valentina, Beresford-Kroeger Diana, Roviello Giovanni N., Old growth forests and large old trees as critical organisms connecting ecosystems and human health. A review, Environmental Chemistry Letters, 20, 2, 2022. Crossref

  2. Costanzo Vincenzo, Gilhen-Baker Melinda, Beresford-Kroeger Diana, Roviello Giovanni N, Tree-inhabiting polypore fungi as sources of a cornucopia of bioactive compounds, Future Microbiology, 17, 12, 2022. Crossref

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