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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Identification and Quantification of Triterpenoids in Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with HPLC-MS/MS Methods

Volume 20, Edição 10, 2018, pp. 919-934
DOI: 10.1615/IntJMedMushrooms.2018027398
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RESUMO

Ganoderma lucidum is one of the most commonly used mushrooms in traditional Chinese medicine, with significant immunomodulatory and antitumor effects. Triterpenoids are deemed to be the main bioactive components in G. lucidum. In this study, high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (MS) and high-performance liquid chromatography-MS/MS methods were used to identify and quantify, respectively, the main triterpenoids in G. lucidum obtained from different sources. The full MS scan with a daughter ion scan was used to identify a variety of potential derivatives of triterpenoids in the mushroom. Multiple reaction monitoring was performed with transitions of m/z—515.2 → 285.1 (quantifier) and 515.2 → 497.2 (qualifier)—to determine the amount of ganoderic acid A. The developed methods were successfully used to analyze 8 G. lucidum samples from the wild and from cultivated and commercial sources. The results show that the content and composition of triterpenoids differed significantly among these samples. A total of 29 triterpenoids were explicitly or tentatively identified in the wild sample, whereas 23 triterpenoids were found in the cultured sample and 17 in the commercial sample. The results of this study provide a foundation for further research on chemical constituents of, identification of metabolites in, and quality control of the G. lucidum mushroom.

CITADO POR
  1. Chang Wei-Ting, Gao Zi-Han, Lo Yi-Ching, Wu Sheng-Nan, Evidence for Effective Inhibitory Actions on Hyperpolarization-Activated Cation Current Caused by Ganoderma Triterpenoids, the Main Active Constitutents of Ganoderma Spores, Molecules, 24, 23, 2019. Crossref

  2. Wang Zhuo, Wang Hongling, Kang Zongli, Wu You, Xing Yao, Yang Yuhong, Antioxidant and anti-tumour activity of triterpenoid compounds isolated from Morchella mycelium, Archives of Microbiology, 202, 7, 2020. Crossref

  3. Li Changqin, Cui Yiping, Lu Jie, Meng Lijun, Ma Changyang, Liu Zhenhua, Zhang Yan, Kang Wenyi, Spectrum-effect relationship of immunologic activity of Ganoderma lucidum by UPLC-MS/MS and component knock-out method, Food Science and Human Wellness, 10, 3, 2021. Crossref

  4. Adotey Gideon, Alolga Raphael N., Quarcoo Abraham, Gedel Mohammed Ahmed, Anang Abraham K., Holliday John C., Ultra Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry (UPLC-Q-TOF-MS)-based metabolomic analysis of mycelial biomass of three Ganoderma isolates from the Lower Volta River Basin of Ghana, Journal of Pharmaceutical and Biomedical Analysis, 205, 2021. Crossref

  5. Li Baolin, Fan Shuaishuai, Hu Jingnan, Ma Yongben, Feng Yu, Wang Fengxia, Wang Xinguo, Niu Liying, Abdel Azim Nahla S., Phytochemical Analysis Using UPLC-MS/MS Combined with Network Pharmacology Methods to Explore the Biomarkers for the Quality Control of Lingguizhugan Decoction, Evidence-Based Complementary and Alternative Medicine, 2021, 2021. Crossref

  6. Kiss Attila, Grünvald Petra, Ladányi Márta, Papp Viktor, Papp István, Némedi Erzsébet, Mirmazloum Iman, Heat Treatment of Reishi Medicinal Mushroom (Ganoderma lingzhi) Basidiocarp Enhanced Its β-glucan Solubility, Antioxidant Capacity and Lactogenic Properties, Foods, 10, 9, 2021. Crossref

  7. Khan Mohammad Umar, Gautam Gaurav, Jan Bisma, Zahiruddin Sultan, Parveen Rabea, Ahmad Sayeed, Vitamin D from Vegetable VV Sources: Hope for the Future, Phytomedicine Plus, 2, 2, 2022. Crossref

  8. Zhao Hengqiang, Lai Chang-Jiang-Sheng, Yu Yi, Wang Ya-nan, Zhao Yu-Jun, Ma Fangli, Hu Minghua, Guo Juan, Wang Xiao, Guo Lanping, Acidic hydrolysate fingerprints based on HILIC-ELSD/MS combined with multivariate analysis for investigating the quality of Ganoderma lucidum polysaccharides, International Journal of Biological Macromolecules, 163, 2020. Crossref

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