Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
Indexed in
Wound Healing Activity of an Aqueous Extract of the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes)
RESUMO
The Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes) is popular because of its health-promoting properties. The effects of G. lucidum extract on cancer, hypertension, hypercholesterolemia, and hepatitis have been reported by many researchers. This investigation was undertaken to evaluate the healing efficacy of an aqueous lyophilized extract of G. lucidum from the Indian Himalayan region on dermal excision wound in experimental rats. The extract used in the study was found to be rich in total polyphenol and flavonoid contents. The healing efficacy was comparatively assessed with a reference povidone-iodine ointment. The G. lucidum extract showed significant enhanced healing activity, evidenced by an increase in wound contraction, collagen accumulation (hydroxyproline), hexosamine, and total protein contents. Histopathological findings further supported the biochemical indices. The results suggest that aqueous lyophilized extract of G. lucidum possesses significant wound-healing activity.
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Siwulski Marek, Sobieralski Krzysztof, Golak-Siwulska Iwona, Sokół Sławomir, Sękara Agnieszka, Ganoderma lucidum (Curt.: Fr.) Karst. – health-promoting properties. A review, Herba Polonica, 61, 3, 2015. Crossref
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Varghese Ruby, Dalvi Yogesh Bharat, Lamrood Prasad Y., Shinde Bharat P., Nair C. K. K., Historical and current perspectives on therapeutic potential of higher basidiomycetes: an overview, 3 Biotech, 9, 10, 2019. Crossref
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Sharifi-Rad Javad, Butnariu Monica, Ezzat Shahira M., Adetunji Charles Oluwaseun, Imran Muhammad, Sobhani Seyyed Reza, Tufail Tabussam, Hosseinabadi Tahereh, Ramírez-Alarcón Karina, Martorell Miquel, Maroyi Alfred, Martins Natália, Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes, Frontiers in Pharmacology, 11, 2020. Crossref
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Kamdi Sandesh P., Raval Amit, Nakhate Kartik T., Effect of apple peel extract on diabetes-induced peripheral neuropathy and wound injury, Journal of Diabetes & Metabolic Disorders, 20, 1, 2021. Crossref