Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
Indexed in
Anticancer and Antimicrobial Activities and Chemical Composition of the Birch Mazegill Mushroom Lenzites betulina (Higher Basidiomycetes)
RESUMO
The anticancer properties, antibiotic activity, and chemical composition of Lenzites betulina ethanol extract (EE) were evaluated. Eight compounds including 5 sterols were isolated from L. betulina, and 7 compounds were isolated from L. betulina for the first time. The EE displayed strong anticancer activity against tumor cell line MDA-MB-231, with a half maximal inhibitory concentration of 51.46 μg/mL, and there was 83.15% inhibition at a concentration of 200 μg/mL (MTT assay). The antimicrobial activity of the EE was evaluated against 6 microorganisms−Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Fusarium graminearum, Gibberella zeae, and Cercosporella albo-maculans−and the EE showed moderate antibiotic activity. These results suggest that L. betulina could be a good anticancer and antibiotic agent.
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Alves Ricardo, Preto Marco, Vasconcelos Vitor, Oliveira Rui S., Martins Rosário, Cytotoxicity Induced by Extracts ofPisolithus tinctoriusSpores on Human Cancer and Normal Cell Lines—Evaluation of the Anticancer Potential, Journal of Toxicology and Environmental Health, Part A, 78, 13-14, 2015. Crossref
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Zhang Jiao-Jiao, Li Ya, Zhou Tong, Xu Dong-Ping, Zhang Pei, Li Sha, Li Hua-Bin, Bioactivities and Health Benefits of Mushrooms Mainly from China, Molecules, 21, 7, 2016. Crossref
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Hardin Joshua S., Sutton Deanna A., Wiederhold Nathan P., Mele James, Goyal Sunali, Fungal Keratitis Secondary to Trametes betulina: A Case Report and Review of Literature, Mycopathologia, 182, 7-8, 2017. Crossref
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Sytu Marion Ryan C., Camacho Drexel H., Green Synthesis of Silver Nanoparticles (AgNPs) from Lenzites betulina and the Potential Synergistic Effect of AgNP and Capping Biomolecules in Enhancing Antioxidant Activity, BioNanoScience, 8, 3, 2018. Crossref
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Wu Fang, Zhou Li-Wei, Yang Zhu-Liang, Bau Tolgor, Li Tai-Hui, Dai Yu-Cheng, Resource diversity of Chinese macrofungi: edible, medicinal and poisonous species, Fungal Diversity, 98, 1, 2019. Crossref
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Guo Lei, Tan Da‐Cong, Hui Fu‐Yi, Gu Fan, Xiao Kun‐Min, Hua Yan, Optimization of the Cellulase−Ultrasonic Synergistic Extraction Conditions of Polysaccharides from Lenzites betulina , Chemistry & Biodiversity, 16, 11, 2019. Crossref