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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Antibacterial and Antiviral Value of the Genus Ganoderma P. Karst. Species (Aphyllophoromycetideae): A Review

Volume 5, Edição 3, 2003, 12 pages
DOI: 10.1615/InterJMedicMush.v5.i3.20
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RESUMO

Various effective synthetic antibacterial and antiviral agents have been developed, but drug resistance and toxicity may occur. Herbal medicines may represent a safe and useful approach for the treatment of infectious diseases. Ganoderma lucidum and other Ganoderma species, alone or more often in combination with chemotherapeutic agents, have been used to treat chronic infectious diseases such as chronic hepatitis and bronchitis, although there is limited clinical data available. Data from in vitro and in vivo animal studies indicate that G. lucidum and other Ganoderma species exhibit a broad spectrum of antibacterial and antiviral activities. A recent randomized placebo-controlled clinical study indicates that treatment with G. lucidum polysaccharides at 5400 mg/day for 12 weeks caused inhibitory effects on hepatitis B virus (HBV) replication, as indicated by the decreased serum HBV DNA and hepatitis B e antigen (HBeAg) levels. It appears that both polysaccharides and triterpenoids are the major antiviral constituents of Ganoderma species, while the polysaccharides play a more important role for its antibacterial activity. There appears to be a structure–activity relationship for triterpenoid-mediated antiviral effect. The mechanisms for the antibacterial and antiviral activities of G. lucidum and other Ganoderma species are largely undefined. Ganoderma constituents (e.g., polysaccharides and triterpenoids) may inhibit viral replication by interfering with their adsorption, virus-hepatocyte fusion and endocytosis, and viral integration, assembly, and release. Currently available data suggest that G. lucidum and some other Ganoderma species may play an adjunct role for the management of various infectious diseases, and further experimental and clinical studies are needed.

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