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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Chemical Composition and Antiproliferative, Antioxidant, and Proapoptotic Effects of Fruiting Body Extracts of the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), from India

Volume 18, Edição 7, 2016, pp. 599-607
DOI: 10.1615/IntJMedMushrooms.v18.i7.50
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RESUMO

Ganoderma lucidum is a renowned medicinal mushroom exploited as a panacea because of the broad spectrum of its bioactivities, which give it invaluable nutritional and clinical implications. This research was implemented with an incentive to explore and quantify various macromolecules encompassed in the oriental fungus; these vary in concentration with respect to the development/growth phase, host plants, and geographic location of collection. Chemical profiling of G. lucidum confirmed the presence of myco-constituents, their amounts varying in response to extreme climatic conditions. G. lucidum extract exhibited elevated levels of all myco-constituents but flavonoids, which were more pronounced when in a parasitic relationship with their host plants. Proapoptotic efficiency portrayed by the extracts against a prostate cancer cell line (PC-3) was also found to be similar. The samples collected from the Bathinda region, with Azadirachta and Acacia trees as the host plants, showed several-fold augmentation in levels of G. lucidum gredients compared with other variants. Elevated levels of myco-constituents highlight their significance in inhibiting prostate cancer cell proliferation, reducing reactive oxygen species, suppressing invasive potential, and inducing apoptosis. It was thus concluded that G. lucidum grown on Azadirachta plants was more efficient in exhibiting potent biological activities than G. lucidum grown on other host plants.

CITADO POR
  1. Gill Balraj Singh, Navgeet , Mehra Richa, Kumar Vicky, Kumar Sanjeev, Ganoderic acid, lanostanoid triterpene: a key player in apoptosis, Investigational New Drugs, 36, 1, 2018. Crossref

  2. Gill Balraj Singh, Kumar Sanjeev, Navgeet , Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer, Tumor Biology, 39, 3, 2017. Crossref

  3. Gill Balraj Singh, Navgeet , Kumar Sanjeev, Ganoderma lucidumtargeting lung cancer signaling: A review, Tumor Biology, 39, 6, 2017. Crossref

  4. Gill Balraj Singh, Navgeet , Kumar Sanjeev, Antioxidant potential of ganoderic acid in Notch-1 protein in neuroblastoma, Molecular and Cellular Biochemistry, 456, 1-2, 2019. Crossref

  5. Gill Balraj Singh, Mehra Richa, Navgeet , Kumar Sanjeev, Vitex negundo and its medicinal value, Molecular Biology Reports, 45, 6, 2018. Crossref

  6. Sharma Prateek, Kumar Sanjeev, Metformin inhibits human breast cancer cell growth by promoting apoptosis via a ROS-independent pathway involving mitochondrial dysfunction: pivotal role of superoxide dismutase (SOD), Cellular Oncology, 41, 6, 2018. Crossref

  7. Gill Balraj Singh, Navgeet , Qiu Feng, Technologies for extraction and production of bioactive compounds, in Biotechnological Production of Bioactive Compounds, 2020. Crossref

  8. Ahmad Md Faruque, Ganoderma lucidum: A Macro Fungus with Phytochemicals and Their Pharmacological Properties, in Plant and Human Health, Volume 2, 2019. Crossref

  9. Shibu Marthandam Asokan, Shanmugam Tamilselvi, Agrawal Dinesh Chandra, Huang Chih-Yang, Mushrooms: A Wealth of Resource for Prospective Stem Cell-Based Therapies, in Medicinal Mushrooms, 2019. Crossref

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