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ISSN Печать: 1040-8401
ISSN Онлайн: 2162-6472
Indexed in
Immunomodulatory Bonds of the Partnership between Dendritic Cells and T Cells
Краткое описание
By acquiring, processing, and presenting both foreign and self-antigens, dendritic cells (DCs) initiate T cell activation that is shaped through the immunomodulatory functions of a variety of cell-membrane-bound molecules including BTLA-HVEM, CD40-CD40L, CTLA-4-CD80/CD86, CD70-CD27, ICOS-ICOS-L, OX40-OX40L, and PD-L1-PD-1, as well as several key cytokines and enzymes such as interleukin-6 (IL-6), IL-12, IL-23, IL-27, transforming growth factor-beta 1 (TGF-β1), retinaldehyde dehydrogenase (Raldh), and indoleamine 2,3-dioxygenase (IDO). Some of these distinct immunomodulatory signals are mediated by specific subsets of DCs, therefore contributing to the functional specialization of DCs in the priming and regulation of immune responses. In addition to responding to the DC-mediated signals, T cells can reciprocally modulate the immunomodulatory capacities of DCs, further refining immune responses. Here, we review recent studies, particularly in experimental mouse systems, that have delineated the integrated mechanisms of crucial immunomodulatory pathways that enable specific populations of DCs and T cells to work intimately together as single functional units that are indispensable for the maintenance of immune homeostasis.
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Aung Phyu P., Sukswai Narittee, Nejati Reza, Loghavi Sanam, Chen Weina, Torres-Cabala Carlos A., Yin C. Cameron, Konopleva Marina, Zheng Xiaofeng, Wang Jing, Tang Zhenya, Medeiros L. Jeffrey, Prieto Victor G., Pemmaraju Naveen, Khoury Joseph D., PD1/PD-L1 Expression in Blastic Plasmacytoid Dendritic Cell Neoplasm, Cancers, 11, 5, 2019. Crossref
-
Bourque Jessica, Hawiger Daniel, The BTLA–HVEM–CD5 Immunoregulatory Axis–An Instructive Mechanism Governing pTreg Cell Differentiation, Frontiers in Immunology, 10, 2019. Crossref
-
Iberg Courtney A., Hawiger Daniel, Advancing immunomodulation by in vivo antigen delivery to DEC-205 and other cell surface molecules using recombinant chimeric antibodies, International Immunopharmacology, 73, 2019. Crossref
-
Imai Jun, Otani Mayu, Sakai Takahiro, Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation, International Journal of Molecular Sciences, 20, 22, 2019. Crossref
-
Nelson Nicole L.J., Zajd Cheryl M., Lennartz Michelle R., Gosselin Edmund J., Fcγ receptors and toll-like receptor 9 synergize to drive immune complex-induced dendritic cell maturation, Cellular Immunology, 345, 2019. Crossref
-
Azeem Waqas, Bakke Ragnhild Maukon, Appel Silke, Øyan Anne Margrete, Kalland Karl-Henning, Dual Pro- and Anti-Inflammatory Features of Monocyte-Derived Dendritic Cells, Frontiers in Immunology, 11, 2020. Crossref
-
Van Coillie Samya, Wiernicki Bartosz, Xu Jie, Molecular and Cellular Functions of CTLA-4, in Regulation of Cancer Immune Checkpoints, 1248, 2020. Crossref
-
Iberg Courtney A., Hawiger Daniel, Targeting Dendritic Cells with Antigen-Delivering Antibodies for Amelioration of Autoimmunity in Animal Models of Multiple Sclerosis and Other Autoimmune Diseases, Antibodies, 9, 2, 2020. Crossref
-
Imai Jun, Ohashi Sayaka, Sakai Takahiro, Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations: A Review, Pharmaceutics, 12, 2, 2020. Crossref
-
Iberg Courtney A., Hawiger Daniel, Natural and Induced Tolerogenic Dendritic Cells, The Journal of Immunology, 204, 4, 2020. Crossref
-
Du Xiaonan, Li Chenduo, Wang Wenjun, Huang Qiong, Wang Jingjing, Tong Zhaohui, Huang Kewu, Chen Yan, Yuan Huihui, Lv Zhe, Corrigan Chris J., Wang Wei, Ying Sun, IL-33 induced airways inflammation is partially dependent on IL-9, Cellular Immunology, 352, 2020. Crossref
-
Zheng Xue, Sun Chao, Yu Rilei, Chu Xin, Xu Jiahao, Liu Chengcheng, Zhao Miaoqing, Xu Xuelian, Xia Ming, Wang Cheng, CD13-specific ligand facilitates Xanthatin nanomedicine targeting dendritic cells for therapy of refractory allergic rhinitis, International Journal of Pharmaceutics, 577, 2020. Crossref
-
Carranza-León D A, Oeser A, Marton A, Wang P, Gore J C, Titze J, Stein C M, Chung C P, Ormseth M J, Tissue sodium content in patients with systemic lupus erythematosus: association with disease activity and markers of inflammation, Lupus, 29, 5, 2020. Crossref
-
Gallizioli Mattia, Miró-Mur Francesc, Otxoa-de-Amezaga Amaia, Cugota Roger, Salas-Perdomo Angélica, Justicia Carles, Brait Vanessa H., Ruiz-Jaén Francisca, Arbaizar-Rovirosa Maria, Pedragosa Jordi, Bonfill-Teixidor Ester, Gelderblom Mathias, Magnus Tim, Cano Eva, del Fresno Carlos, Sancho David, Planas Anna M., Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs, Cell Reports, 33, 3, 2020. Crossref
-
Pavlovic Kristina, Tristán-Manzano María, Maldonado-Pérez Noelia, Cortijo-Gutierrez Marina, Sánchez-Hernández Sabina, Justicia-Lirio Pedro, Carmona M. Dolores, Herrera Concha, Martin Francisco, Benabdellah Karim, Using Gene Editing Approaches to Fine-Tune the Immune System, Frontiers in Immunology, 11, 2020. Crossref
-
Kim Kyungeun, Khang Dongwoo, <p>Past, Present, and Future of Anticancer Nanomedicine</p>, International Journal of Nanomedicine, Volume 15, 2020. Crossref
-
Barut G. Tuba, Lischer Heidi E. L., Bruggmann Rémy, Summerfield Artur, Talker Stephanie C., Transcriptomic profiling of bovine blood dendritic cells and monocytes following TLR stimulation, European Journal of Immunology, 50, 11, 2020. Crossref
-
Opejin Adeleye, Surnov Alexey, Misulovin Ziva, Pherson Michelle, Gross Cindy, Iberg Courtney A., Fallahee Ian, Bourque Jessica, Dorsett Dale, Hawiger Daniel, A Two-Step Process of Effector Programming Governs CD4+ T Cell Fate Determination Induced by Antigenic Activation in the Steady State, Cell Reports, 33, 8, 2020. Crossref
-
Jafarzadeh Abdollah, Nemati Maryam, Jafarzadeh Sara, Chauhan Prashant, Saha Bhaskar, The immunomodulatory potentials of interleukin‐27 in airway allergies, Scandinavian Journal of Immunology, 93, 2, 2021. Crossref
-
Pelosi Andrea, Fiore Piera Filomena, Di Matteo Sabina, Veneziani Irene, Caruana Ignazio, Ebert Stefan, Munari Enrico, Moretta Lorenzo, Maggi Enrico, Azzarone Bruno, Pediatric Tumors-Mediated Inhibitory Effect on NK Cells: The Case of Neuroblastoma and Wilms’ Tumors, Cancers, 13, 10, 2021. Crossref
-
Shen Pei-Xin, Li Xing, Deng Si-Ying, Zhao Li, Zhang Yan-Yan, Deng Xin, Han Bing, Yu Jie, Li Yin, Wang Zhe-Zhi, Zhang Yuan, Urolithin A ameliorates experimental autoimmune encephalomyelitis by targeting aryl hydrocarbon receptor, EBioMedicine, 64, 2021. Crossref
-
Tang Philip Chiu-Tsun, Chan Alex Siu-Wing, Zhang Cai-Bin, García Córdoba Cristina Alexandra, Zhang Ying-Ying, To Ka-Fai, Leung Kam-Tong, Lan Hui-Yao, Tang Patrick Ming-Kuen, TGF-β1 Signaling: Immune Dynamics of Chronic Kidney Diseases, Frontiers in Medicine, 8, 2021. Crossref
-
Solé Patricia, Santamaria Pere, Re-Programming Autoreactive T Cells Into T-Regulatory Type 1 Cells for the Treatment of Autoimmunity, Frontiers in Immunology, 12, 2021. Crossref
-
Oner Fatma, Alvarez Carla, Yaghmoor Wael, Stephens Danielle, Hasturk Hatice, Firatli Erhan, Kantarci Alpdogan, Resolvin E1 Regulates Th17 Function and T Cell Activation, Frontiers in Immunology, 12, 2021. Crossref
-
Han Limin, Fu Qiang, Deng Chuan, Luo Li, Xiang Tengxiao, Zhao Hailong, Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour, Scandinavian Journal of Immunology, 95, 1, 2022. Crossref
-
Ness Sara, Lin Shiming, Gordon John R., Regulatory Dendritic Cells, T Cell Tolerance, and Dendritic Cell Therapy for Immunologic Disease, Frontiers in Immunology, 12, 2021. Crossref
-
Talayev VYu, Svetlova MV, Zaichenko IY, Babaykina ON, Voronina EV, Methods of Studying Human Dendritic Cells Applicable to Assessing Vaccine Efficacy, ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, 2021. Crossref
-
Zheng Guoxu, Guo Zhangyan, Li Weimiao, Xi Wenjin, Zuo Baile, Zhang Rui, Wen Weihong, Yang An-Gang, Jia Lintao, Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab, Signal Transduction and Targeted Therapy, 6, 1, 2021. Crossref
-
Fiore Piera Filomena, Vacca Paola, Tumino Nicola, Besi Francesca, Pelosi Andrea, Munari Enrico, Marconi Marcella, Caruana Ignazio, Pistoia Vito, Moretta Lorenzo, Azzarone Bruno, Wilms’ Tumor Primary Cells Display Potent Immunoregulatory Properties on NK Cells and Macrophages, Cancers, 13, 2, 2021. Crossref
-
Wright Sabrina, Hennessy Conor, Hester Joanna, Issa Fadi, Chimeric Antigen Receptors and Regulatory T Cells: The Potential for HLA-Specific Immunosuppression in Transplantation, Engineering, 10, 2022. Crossref
-
Harriman Rian, Lewis Jamal S., Bioderived materials that disarm the gut mucosal immune system: Potential lessons from commensal microbiota, Acta Biomaterialia, 133, 2021. Crossref
-
Bourque Jessica, Hawiger Daniel, Variegated Outcomes of T Cell Activation by Dendritic Cells in the Steady State, The Journal of Immunology, 208, 3, 2022. Crossref
-
Gao Yang, Cheng Jishuai, Xu Xingli, Li Xueqi, Zhang Jingjing, Ma Danjing, Jiang Guorun, Liao Yun, Fan Shengtao, Niu Zhenye, Yue Rong, Chang Penglan, Zeng Fengyuan, Duan Suqin, Meng Ziyan, Xu Xiangxiong, Li Xinghang, Li Dandan, Yu Li, Ping Lifen, Zhao Heng, Guo Mingtian, Wang Lichun, Wang Yafang, Zhang Ying, Li Qihan, HSV-1 Infection of Epithelial Dendritic Cells Is a Critical Strategy for Interfering with Antiviral Immunity, Viruses, 14, 5, 2022. Crossref
-
Bourque Jessica, Hawiger Daniel, Applications of Antibody-Based Antigen Delivery Targeted to Dendritic Cells In Vivo, Antibodies, 11, 1, 2022. Crossref
-
Guo Bingnan, Peng Yigen, Gu Yuting, Zhong Yi, Su Chenglei, Liu Lin, Chai Dafei, Song Tengfei, Zhao Ningjun, Yan Xianliang, Xu Tie, Resveratrol pretreatment mitigates LPS-induced acute lung injury by regulating conventional dendritic cells’ maturation and function, Open Life Sciences, 16, 1, 2021. Crossref
-
Lutgens Esther, Joffre Jeremie, van Os Bram, Ait-Oufella Hafid, Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies, Atherosclerosis, 335, 2021. Crossref
-
Schmid Hannes, Ribeiro Emmanuelle M., Secker Kathy-Ann, Duerr-Stoerzer Silke, Keppeler Hildegard, Dong Ruoyun, Munz Timo, Schulze-Osthoff Klaus, Hailfinger Stephan, Schneidawind Corina, Schneidawind Dominik, Human invariant natural killer T cells promote tolerance by preferential apoptosis induction of conventional dendritic cells, Haematologica, 107, 2, 2021. Crossref
-
Wang Hong-yun, Ye Jun-rui, Cui Li-yuan, Chu Shi-feng, Chen Nai-hong, Regulatory T cells in ischemic stroke, Acta Pharmacologica Sinica, 43, 1, 2022. Crossref
-
Barrett Lucy W, Fear Vanessa S, Foley Bree, Audsley Katherine, Barnes Samantha, Newnes Hannah, McDonnell Alison, Wood Fiona M, Fear Mark W, Waithman Jason, Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells, Burns & Trauma, 10, 2022. Crossref
-
Wang Junlin, Li Xiaoling, Liu Chunlei, Wang Shuli, Li Jianqin, Effect of BCG HSP70 Gene Transfection on Dendritic Cells Derived From Bone Marrow in Children With Acute Leukemia, Journal of Pediatric Hematology/Oncology, 44, 6, 2022. Crossref
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de Cos Marina, Xipell Marc, García-Herrera Adriana, Lledo Gema M., Guillen Elena, Blasco Miquel, Espinosa Gerard, Cervera Ricard, Quintana Luis F., Assessing and counteracting fibrosis is a cornerstone of the treatment of CKD secondary to systemic and renal limited autoimmune disorders, Autoimmunity Reviews, 21, 3, 2022. Crossref
-
Iberg Courtney A., Bourque Jessica, Fallahee Ian, Son Sungho, Hawiger Daniel, TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells, Cell Reports, 39, 2, 2022. Crossref
-
Zhao Yongmei, Liu Tianqing, Zhou Mengjiao, Immune-Cell-Derived Exosomes for Cancer Therapy, Molecular Pharmaceutics, 19, 9, 2022. Crossref
-
Neyrinck-Leglantier Déborah, Tamagne Marie, L’honoré Sasha, Cagnet Léonie, Pakdaman Sadaf, Marchand Alexandre, Pirenne France, Vingert BenoÎt, Autologous blood extracellular vesicles and specific CD4+ T-cell co-activation, Frontiers in Immunology, 13, 2022. Crossref
-
Wen Mou, Ying Yuanlin, Xiao Xiang, Arnold Preston R., Wang Guangchuan, Chu Xiufeng, Ghobrial Rafik M., Li Xian C., Ox40-Cre–mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia, JCI Insight, 7, 23, 2022. Crossref
-
Karayama Masato, Mizoguchi Yukihiro, Inoue Yusuke, Hozumi Hironao, Suzuki Yuzo, Furuhashi Kazuki, Fujisawa Tomoyuki, Enomoto Noriyuki, Nakamura Yutaro, Inui Naoki, Suda Takafumi, Kitano Shigehisa, Aoki Kazunori, Yamada Yasuhide, Association between increased peripheral blood CD86-positive plasmacytoid dendritic cells and immune-related adverse events in patients with non-small cell lung cancer, Global Health & Medicine, 4, 6, 2022. Crossref
-
Meng Ru, Fu Yong, Zhang Yaogang, Mou Yalin, Liu Gongguan, Fan Haining, Indoleamine 2,3-dioxygenase 1 signaling orchestrates immune tolerance in Echinococcus multilocularis-infected mice, Frontiers in Immunology, 13, 2022. Crossref