Доступ предоставлен для: Guest
Critical Reviews™ in Immunology

Выходит 6 номеров в год

ISSN Печать: 1040-8401

ISSN Онлайн: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

T Cell Activation Pathways: B7, LFA-3, and ICAM-1 Shape Unique T Cell Profiles

Том 15, Выпуск 3-4, 1995, pp. 235-253
DOI: 10.1615/CritRevImmunol.v15.i3-4.30
Get accessGet access

Краткое описание

Two signals are required for induction of cell proliferation and cytokine production in resting T cells. Occupancy of the T cell receptor by antigen/MHC complexes delivers the first signal to the T cell, while the second signal is provided by interaction with costimulatory ligands on APC. CD2, LFA-1, and CD28 are the major costimulatory and adhesive molecules on T cells and bind to the LFA-3, ICAM-1 and B7 ligands, respectively, on APC. LFA-3 plays a central role for naive and memory T helper cells during the early phase of an immune response. The LFA-3/CD2 pathway initiates strong antigen-independent cell adhesion, substantial expansion of naive T helper cells, and induction of large amounts of IFN-γ in memory cells.
The release of IFN-γ may upregulate expression of ICAM-1 and B7 on APC and allows multiple adhesion pathways to amplify the immune response. The LFA- 1/ICAM-l pathway stimulates adhesion and cell proliferation more efficiently in memory T helper cells than in naive cells. Further, the results suggest that naive T helper cells express functionally inactive LFA-1 molecules on the cell surface, which may have a physiological role in keeping these cells in a resting state. B7 costimulation superinduces IL-2 production in both naive and memory T helper cells and generates long-lasting cell proliferation. This permits transition from an autocrine to a paracrine immune response. Coexpression of B7/LFA-3 provides an optimal APC function and enables a vigorous T cell response to minute amounts of antigen. AP-1 and NF-κB transcription factors are involved in the induction of several cytokine gene promoters and play a central role in the regulation of IL-2 gene transcription. LFA-3 costimulation only moderately enhances AP-1 DNA-binding activity and does not influence the NF-κB activity induced by TCR engagement, whereas B7 costimulation induces large amounts of NF-κB and AP-1 activity in T helper cells. The costimulatory ligands represent a family of adhesion molecules with considerable redundancy. Interfamily redundancy of LFA-3, B7, and ICAM ligands offers an opportunity to regulate distinct T cell response profiles in various microenvironments at separate time points of an immune response.

ЦИТИРОВАНО В
  1. Hilliard Brendan A., Mason Nicola, Xu Lingyun, Sun Jing, Lamhamedi-Cherradi Salah-Eddine, Liou Hsiou-Chi, Hunter Christopher, Chen Youhai H., Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation, Journal of Clinical Investigation, 110, 6, 2002. Crossref

  2. Wanschitz Felix, Nell Andrea, Patruta Sanda, Wagner Arne, Ewers Rolf, Influence of three currently used bone replacing materials on thein vitroproliferation of human peripheral blood mononuclear cells, Clinical Oral Implants Research, 16, 5, 2005. Crossref

  3. Hewson Tim, Lone Nazir, Moore Marilyn, Howie Sarah, Interactions of HIV-1 with antigen-presenting cells, Immunology and Cell Biology, 77, 4, 1999. Crossref

  4. Prinz JC, The role of T cells in psoriasis, Journal of the European Academy of Dermatology and Venereology, 17, 3, 2003. Crossref

  5. Dunnion D. J., Cywinski A. L., Tucker V. C., Murray A. K., Rickinson A. B., Coulie P., Browning M. J., Human antigen-presenting cell/tumour cell hybrids stimulate strong allogeneic responses and present tumour-associated antigens to cytotoxic T cells in vitro , Immunology, 98, 4, 1999. Crossref

  6. Hall Simon R., Rhodes John, Schiff base-mediated co-stimulation primes the T-cell-receptor-dependent calcium signalling pathway in CD4 T cells, Immunology, 104, 1, 2001. Crossref

  7. ABRAMS SCOTT I., Development of Epitope-Specific Immunotherapies for Human Malignancies and Premalignant Lesions Expressing Mutated ras Genes, in Gene Therapy of Cancer, 2002. Crossref

  8. Schlom Jeffrey, Hodse James W., The diversity of T-cell co-stimulation in the induction of antitumor immunity, Immunological Reviews, 170, 1, 1999. Crossref

  9. Salucci V., Lena A. M., Ciliberto G., Scarselli E., La Monica N., Adenovirus Transduction and Culture Conditions Affect the Immunogenicity of Murine Dendritic Cells, Scandinavian Journal of Immunology, 62, 3, 2005. Crossref

  10. Nicola Nicos A., Hilton Douglas J., General Classes and Functions of Four-Helix Bundle Cytokines, in Cytokines, 52, 1998. Crossref

  11. Taylor Alison, Verhagen Johan, Blaser Kurt, Akdis Mubeccel, Akdis Cezmi A., Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells, Immunology, 117, 4, 2006. Crossref

  12. Riley Roger S., Mageau Ronald, Ben-Ezra Jonathan, Laboratory Evaluation of the Cellular Immune System, in Henry's Clinical Diagnosis and Management by Laboratory Methods, 2011. Crossref

  13. Hilliard Brendan A., Mason Nicola, Xu Lingyun, Sun Jing, Lamhamedi-Cherradi Salah-Eddine, Liou Hsiou-Chi, Hunter Christopher, Chen Youhai H., Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation, Journal of Clinical Investigation, 110, 6, 2002. Crossref

  14. Kenneth B. Gordon, Thomas S. McCormick, Evolution of Biologic Therapies for the Treatment of Psoriasis, SKINmed: Dermatology for the Clinician, 2, 5, 2003. Crossref

  15. Lagaudrière-Gesbert Cécile, Lebel-Binay Sophie, Hubeau Cedric, Fradelizi Didier, Conjeaud Hélène, Signaling through the tetraspanin CD82 triggers its association with the cytoskeleton leading to sustained morphological changes and T cell activation, European Journal of Immunology, 28, 12, 1998. Crossref

  16. Remondo Cinzia, Gulley James L, Immunotherapy for prostate cancer, in Targeted Therapies for Castration-Resistant Prostate Cancer, 2011. Crossref

  17. Altin Joseph G, Sloan Erica K, The role of CD45 and CD45-associated molecules in T cell activation, Immunology and Cell Biology, 75, 5, 1997. Crossref

  18. La Flamme Anne C., Kahn Stuart J., Rudensky Alexander Y., Van Voorhis Wesley C., Trypanosoma cruzi-infected macrophages are defective in major histocompatibility complex class II antigen presentation, European Journal of Immunology, 27, 12, 1997. Crossref

  19. Hilliard Brendan A., Mason Nicola, Xu Lingyun, Sun Jing, Lamhamedi-Cherradi Salah-Eddine, Liou Hsiou-Chi, Hunter Christopher, Chen Youhai H., Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation, Journal of Clinical Investigation, 110, 6, 2002. Crossref

  20. McMichael Amy J., Excimer Laser: A Module of the Alopecia Areata Common Protocol, Journal of Investigative Dermatology Symposium Proceedings, 16, 1, 2013. Crossref

  21. Ward Robert C., Kaufman Howard L., Targeting Costimulatory Pathways for Tumor Immunotherapy, International Reviews of Immunology, 26, 3-4, 2007. Crossref

  22. Clinical Protocol: A Phase I Trial of Intra Lesional RV-B7.1 Vaccine in the Treatment of Malignant Melanoma. Albert Einstein Center, Bronx, New York., Human Gene Therapy, 11, 7, 2000. Crossref

  23. EVANS GERALD A., FARRAR WILLIAM L., Purification of the Renaturable Protein Kinase PK55 by Preparative Isoelectric Focusing and High Performance Electrophoretic Chromatography and the Generation of PK55 Monoclonal Antibodies by In Vitro B Cell Stimulation, Hybridoma, 16, 6, 1997. Crossref

  24. Avitahl Nicole, Winandy Susan, Friedrich Christof, Jones Beverly, Ge Yimin, Georgopoulos Katia, Ikaros Sets Thresholds for T Cell Activation and Regulates Chromosome Propagation, Immunity, 10, 3, 1999. Crossref

  25. Palena Claudia, Abrams Scott I., Schlom Jeffrey, Hodge James W., , 95, 2006. Crossref

  26. Schlom Jeffrey, Tsang Kwong-Yok, Kantor Judith A, Abrams Scott I, Zaremba Sam, Greiner John, Hodge James W, Cancer vaccine development, Expert Opinion on Investigational Drugs, 7, 9, 1998. Crossref

  27. Gandolfi A., Cell receptor occupancy during cell-to-cell adhesion, Mathematical and Computer Modelling, 31, 4-5, 2000. Crossref

  28. Grosenbach Douglas W., Schlom Jeffrey, Gritz Linda, Gómez Yafal Alicia, Hodge James W., A recombinant vector expressing transgenes for four T-cell costimulatory molecules (OX40L, B7-1, ICAM-1, LFA-3) induces sustained CD4+ and CD8+ T-cell activation, protection from apoptosis, and enhanced cytokine production, Cellular Immunology, 222, 1, 2003. Crossref

  29. Eriksson Håkan, Proteolytic cleavage of MHC class I by complement C1-esterases—an overlooked mechanism?, Immunotechnology, 2, 3, 1996. Crossref

  30. Briones J., Timmerman J. M., Panicalli D. L., Levy R., Antitumor Immunity After Vaccination With B Lymphoma Cells Overexpressing a Triad of Costimulatory Molecules, JNCI Journal of the National Cancer Institute, 95, 7, 2003. Crossref

  31. Shankar Pragyna, Schlom Jeffrey, Hodge James W., Enhanced activation of rhesus T cells by vectors encoding a triad of costimulatory molecules (B7-1, ICAM-1, LFA-3), Vaccine, 20, 5-6, 2001. Crossref

  32. Britten Cedrik M, Meyer Ralf G, Kreer Tanja, Drexler Ingo, Wölfel Thomas, Herr Wolfgang, The use of HLA-A*0201-transfected K562 as standard antigen-presenting cells for CD8+ T lymphocytes in IFN-γ ELISPOT assays, Journal of Immunological Methods, 259, 1-2, 2002. Crossref

  33. Costa Maria Fernanda S., Nihei Jorge, Mengel José, Henriques Maria Graças, Penido Carmen, Requirement of L-selectin for γδ T lymphocyte activation and migration during allergic pleurisy: Co-relation with eosinophil accumulation, International Immunopharmacology, 9, 3, 2009. Crossref

  34. Bazzi Samer, Modjtahedi Helmout, Mudan Satvinder, Akle Charles, Bahr Georges M., Analysis of the immunomodulatory properties of two heat-killed mycobacterial preparations in a human whole blood model, Immunobiology, 220, 12, 2015. Crossref

  35. Hodge James W, Tsang Kwong-Yok, Poole Diane J, Schlom Jeffrey, General Keynote: Vaccine Strategies for the Therapy of Ovarian Cancer, Gynecologic Oncology, 88, 1, 2003. Crossref

  36. Framson Paul E., Cho Diane H., Lee Lawrence Y., Hershberg Robert M., Polarized expression and function of the costimulatory molecule CD58 on human intestinal epithelial cells, Gastroenterology, 116, 5, 1999. Crossref

  37. Müller-Alouf Heide, Gerlach Dieter, Desreumaux Pierre, Leportier Christelle, Alouf Joseph E., Capron Monique, Streptococcal pyrogenic exotoxin A (SPE A) superantigen induced production of hematopoietic cytokines, IL-12 and IL-13 by human peripheral blood mononuclear cells, Microbial Pathogenesis, 23, 5, 1997. Crossref

  38. Zhou Hao, Zou Ping, Chen Zhi-chao, You Yong, A novel vicious cycle cascade in tumor chemotherapy, Medical Hypotheses, 69, 6, 2007. Crossref

  39. Mehlis Stephanie L, Gordon Kenneth B, The immunology of psoriasis and biologic immunotherapy, Journal of the American Academy of Dermatology, 49, 2, 2003. Crossref

  40. Linton Phyllis-Jean, Lustgarten Joseph, Thoman Marilyn, T cell function in the aged: Lessons learned from animal models, Clinical and Applied Immunology Reviews, 6, 2, 2006. Crossref

  41. Tzu Julia, Mamelak Adam J., Sauder Daniel N., Current advancements in the treatment of psoriasis: Immunobiologic agents, Clinical and Applied Immunology Reviews, 6, 2, 2006. Crossref

  42. Ginn-Pease Margaret E, Whisler Ronald L, Redox Signals and NF-κB Activation in T Cells, Free Radical Biology and Medicine, 25, 3, 1998. Crossref

  43. Teschner D., Wenzel G., Distler E., Schnürer E., Theobald M., Neurauter A. A., Schjetne K., Herr W., In Vitro Stimulation and Expansion of Human Tumour-Reactive CD8+ Cytotoxic T Lymphocytes by Anti-CD3/CD28/CD137 Magnetic Beads, Scandinavian Journal of Immunology, 74, 2, 2011. Crossref

  44. Tannenbaum Charles S., Hamilton Thomas A., Immune-inflammatory mechanisms in IFNγ-mediated anti-tumor activity, Seminars in Cancer Biology, 10, 2, 2000. Crossref

  45. Taylor Alison, Verhagen Johan, Akkoç Tunç, Wenig Renate, Flory Egbert, Blaser Kurt, Akdis Mübeccel, Akdis Cezmi A., IL-10 suppresses CD2-mediated T cell activation via SHP-1, Molecular Immunology, 46, 4, 2009. Crossref

  46. Hui George, Hashimoto Caryn, The requirement of CD80, CD86, and ICAM-1 on the ability of adjuvant formulations to potentiate antibody responses to a Plasmodium falciparum blood-stage vaccine, Vaccine, 25, 51, 2007. Crossref

  47. Hodge James W, Grosenbach Douglas W, Schlom Jeffrey, Vector-based delivery of tumor-associated antigens and T-cell co-stimulatory molecules in the induction of immune responses and anti-tumor immunity, Cancer Detection and Prevention, 26, 4, 2002. Crossref

  48. Sporici Romeo A., Perrin Peter J., Costimulation of Memory T-Cells by ICOS: A Potential Therapeutic Target for Autoimmunity?, Clinical Immunology, 100, 3, 2001. Crossref

  49. Rad Ariel N, Schlom Jeffrey, Hodge James W, Vector-driven hyperexpression of a triad of costimulatory molecules confers enhanced T-cell stimulatory capacity to DC precursors, Critical Reviews in Oncology/Hematology, 39, 1-2, 2001. Crossref

  50. Hodge James W, Grosenbach Douglas W, Rad Ariel N, Giuliano Mariateresa, Sabzevari Helen, Schlom Jeffrey, Enhancing the potency of peptide-pulsed antigen presenting cells by vector-driven hyperexpression of a triad of costimulatory molecules, Vaccine, 19, 25-26, 2001. Crossref

  51. Kim Hye-Ran, Jeon Byeong-Hun, Lee Hyun-Su, Im Sin-Hyeog, Araki Masatake, Araki Kimi, Yamamura Ken-ichi, Choi Suck-Chei, Park Do-Sim, Jun Chang-Duk, IGSF4 is a novel TCR ζ-chain–interacting protein that enhances TCR-mediated signaling, Journal of Experimental Medicine, 208, 12, 2011. Crossref

  52. Marlin Steven D., Rothlein Robert, Intercellular Adhesion Molecules: ICAM-1, ICAM-2 And ICAM-3, in Encyclopedia of Immunology, 1998. Crossref

  53. Rakasz Eva, Sandor Matyas, Hagen Michael, Lynch Richard G., Activation features of intraepithelial γδ T-cells of the murine vagina, Immunology Letters, 54, 2-3, 1996. Crossref

  54. Vanderlugt Carol L, Rahbe Sandra M, Elliott Peter J, Dal Canto Mauro C, Miller Stephen D, Treatment of Established Relapsing Experimental Autoimmune Encephalomyelitis with the Proteasome Inhibitor PS-5191, Journal of Autoimmunity, 14, 3, 2000. Crossref

  55. Hodge J. W., Rad A. N., Grosenbach D. W., Sabzevari H., Yafal A. G., Gritz L., Schlom J., Enhanced Activation of T Cells by Dendritic Cells Engineered to Hyperexpress a Triad of Costimulatory Molecules, JNCI Journal of the National Cancer Institute, 92, 15, 2000. Crossref

  56. Kohm Adam P., Miller Stephen D., Role of ICAM-1 and P-selectin expression in the development and effector function of CD4+CD25+regulatory T cells, Journal of Autoimmunity, 21, 3, 2003. Crossref

  57. Findlay Lucy, Sharp Giles, Fox Bernard, Ball Christina, Robinson C. Jane, Bird Christopher, Stebbings Richard, Eastwood David, Wadhwa Meenu, Poole Stephen, Thorpe Robin, Thorpe Susan J., Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture, Cytokine, 55, 1, 2011. Crossref

  58. Madan Ravi A, Arlen Philip M, Gulley James L, PANVAC™-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinoma, Expert Opinion on Biological Therapy, 7, 4, 2007. Crossref

  59. Kalamasz Dale, Long S. A., Taniguchi Ruth, Buckner Jane H., Berenson Ronald J., Bonyhadi Mark, Optimization of Human T-Cell Expansion Ex Vivo Using Magnetic Beads Conjugated with Anti-CD3 and Anti-CD28 Antibodies, Journal of Immunotherapy, 27, 5, 2004. Crossref

  60. Dalirfardouei Razieh, Karimi Gholamreza, Jamialahmadi Khadijeh, Molecular mechanisms and biomedical applications of glucosamine as a potential multifunctional therapeutic agent, Life Sciences, 152, 2016. Crossref

  61. Schlom J., Sabzevari H., Grosenbach D. W., Hodge J. W., A Triad of Costimulatory Molecules Synergize to Amplify T‐‐Cell Activation in Both Vector‐‐Based and Vector‐‐Infected Dendritic Cell Vaccines, Artificial Cells, Blood Substitutes, and Biotechnology, 31, 2, 2003. Crossref

  62. Madan Ravi A, Arlen Philip M, Mohebtash Mahsa, Hodge James W, Gulley James L, Prostvac-VF: a vector-based vaccine targeting PSA in prostate cancer, Expert Opinion on Investigational Drugs, 18, 7, 2009. Crossref

  63. Rocha-Perugini Vera, Sánchez-Madrid Francisco, Martínez del Hoyo Gloria, Function and Dynamics of Tetraspanins during Antigen Recognition and Immunological Synapse Formation, Frontiers in Immunology, 6, 2016. Crossref

  64. Dangles Virginie, Validire Pierre, Wertheimer Mireille, Richon Sophie, Bovin Christophe, Zeliszewski Dominique, Vallancien Guy, Bellet Dominique, Impact of human bladder cancer cell architecture on autologous T-lymphocyte activation, International Journal of Cancer, 98, 1, 2002. Crossref

  65. A Phase I Trial of Intralesional rV-Tricom Vaccine in the Treatment of Malignant Melanoma, Human Gene Therapy, 12, 11, 2001. Crossref

  66. Cole Grace, Dunne Nicholas J., McCarthy Helen O., Microneedles for Gene Therapy: Overcoming Extracellular and Intracellular Barriers, in Microneedles for Drug and Vaccine Delivery and Patient Monitoring, 2018. Crossref

  67. Agrawal Babita, Gupta Nancy, Konowalchuk Jeffrey D., MUC1 Mucin: A Putative Regulatory (Checkpoint) Molecule of T Cells, Frontiers in Immunology, 9, 2018. Crossref

  68. Lausen Mads, Poulsen Thomas B.G., Christiansen Gunna, Kastaniegaard Kenneth, Stensballe Allan, Birkelund Svend, Proteomic analysis of lipopolysaccharide activated human monocytes, Molecular Immunology, 103, 2018. Crossref

  69. Uzendoski Kerry, Kantor Judy A., Abrams Scott I., Schlom Jeffrey, Hodge James W., Construction and Characterization of a Recombinant Vaccinia Virus Expressing Murine Intercellular Adhesion Molecule-1: Induction and Potentiation of Antitumor Responses, Human Gene Therapy, 8, 7, 1997. Crossref

  70. Intra-Lesional rF-B7.1 Versus rF-TRICOM Vaccine in the Treatment of Metastatic Cancer, Human Gene Therapy, 14, 8, 2003. Crossref

  71. Pinto Bruna, Medeiros Nayara, Fontes-Cal Tereza, Naziazeno Isabela, Correa-Oliveira Rodrigo, Dutra Walderez, Gomes Juliana, The Role of Co-Stimulatory Molecules in Chagas Disease, Cells, 7, 11, 2018. Crossref

  72. El Menshawy Nadia, Eissa Mohammed, Abdeen Hanaa M., Elkhamisy Enas M., Joseph Nabil, CD58; leucocyte function adhesion-3 (LFA-3) could be used as a differentiating marker between immune and non-immune thyroid disorders, Comparative Clinical Pathology, 27, 3, 2018. Crossref

  73. Agrawal Babita, New therapeutic targets for cancer: the interplay between immune and metabolic checkpoints and gut microbiota, Clinical and Translational Medicine, 8, 1, 2019. Crossref

  74. Wolk Kerstin, Döcke Wolf-Dietrich, von Baehr Volker, Volk Hans-Dieter, Sabat Robert, Impaired antigen presentation by human monocytes during endotoxin tolerance, Blood, 96, 1, 2000. Crossref

  75. Hodge J. W., Schlom J., Costimulatory Molecules in Vaccine Design, in Therapeutic Vaccination Strategies, 2000. Crossref

  76. Madan Ravi A., Gulley James L., Celestin Jackie, Arlen Philip M., Schlom Jeffrey, Cancer Immunology, Immunotherapeutics, and Vaccine Approaches, in Drug Management of Prostate Cancer, 2010. Crossref

  77. Murad Kari L., Gosselin Edmund J., Eaton John W., Scott Mark D., Stealth Cells: Prevention of Major Histocompatibility Complex Class II-Mediated T-Cell Activation by Cell Surface Modification, Blood, 94, 6, 1999. Crossref

  78. Naisbitt Dean J., Gordon Sfraser, Pirmohamed Munir, Park Bkevin, Immunological Principles of Adverse Drug Reactions, Drug Safety, 23, 6, 2000. Crossref

  79. Gulley James L., Arlen Philip M., Schlom Jeffrey, Pox Viral Vaccines, in Handbook of Cancer Vaccines, 2004. Crossref

  80. Newrzela Sebastian, Gunda Brandenburg, Laer Dorothee von, T Cell Culture for Gammaretroviral Transfer, in Genetic Modification of Hematopoietic Stem Cells, 506, 2009. Crossref

  81. Stavridis John C., Oxidative Activation of Transcription Factor Pathways by Cigarette Smoke Oxidants, in Oxidation: The Cornerstone of Carcinogenesis, 2008. Crossref

  82. Orlik Christian, Deibel Daniel, Küblbeck Johanna, Balta Emre, Ganskih Sabina, Habicht Jüri, Niesler Beate, Schröder-Braunstein Jutta, Schäkel Knut, Wabnitz Guido, Samstag Yvonne, Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin, Cellular & Molecular Immunology, 17, 4, 2020. Crossref

  83. Chen Audrey M., Scott Mark D., Current and Future Applications of Immunological Attenuation via Pegylation of Cells and Tissue, BioDrugs, 15, 12, 2001. Crossref

  84. Villegas Eric N., Lieberman Linda A., Mason Nicola, Blass Sarah L., Zediak Valerie P., Peach Robert, Horan Tom, Yoshinaga Steve, Hunter Christopher A., A Role for Inducible Costimulator Protein in the CD28- Independent Mechanism of Resistance toToxoplasma gondii, The Journal of Immunology, 169, 2, 2002. Crossref

  85. Burkly Linda C., CD40L Pathway Blockade as an Approach to Immunotherapy, in Hemophilia Care in the New Millennium, 489, 2001. Crossref

  86. Wolk Kerstin, Döcke Wolf-Dietrich, von Baehr Volker, Volk Hans-Dieter, Sabat Robert, Impaired antigen presentation by human monocytes during endotoxin tolerance, Blood, 96, 1, 2000. Crossref

  87. Murad Kari L., Gosselin Edmund J., Eaton John W., Scott Mark D., Stealth Cells: Prevention of Major Histocompatibility Complex Class II-Mediated T-Cell Activation by Cell Surface Modification, Blood, 94, 6, 1999. Crossref

  88. Farsaci Benedetto, Kwilas Anna, Hodge James W., Design, development, and translation of poxvirus-based vaccines for cancer, in Cancer Vaccines: From Research to Clinical Practice, 2011. Crossref

  89. Palena Claudia, Foon Kenneth A., Panicali Dennis, Yafal Alicia Gómez, Chinsangaram Jarasvech, Hodge James W., Schlom Jeffrey, Tsang Kwong Y., Potential approach to immunotherapy of chronic lymphocytic leukemia (CLL): enhanced immunogenicity of CLL cells via infection with vectors encoding for multiple costimulatory molecules, Blood, 106, 10, 2005. Crossref

  90. Ramkumar Poornima, Abarientos Anthony B., Tian Ruilin, Seyler Meghan, Leong Jaime T., Chen Merissa, Choudhry Priya, Hechler Torsten, Shah Nina, Wong Sandy W., Martin Thomas G., Wolf Jeffrey L., Roybal Kole T., Pahl Andreas, Taunton Jack, Wiita Arun P., Kampmann Martin, CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma, Blood Advances, 4, 13, 2020. Crossref

  91. Li Yan, Zhu Min, Huo Yani, Zhang Xuerong, Liao Ming, Anti‑fibrosis activity of combination therapy with epigallocatechin gallate, taurine and genistein by regulating glycolysis, gluconeogenesis, and ribosomal and lysosomal signaling pathways in HSC‑T6 cells, Experimental and Therapeutic Medicine, 2018. Crossref

  92. Khongthong Sunisa, Theapparat Yongyuth, Roekngam Natthrit, Tantisuwanno Chinnapatch, Otto Michael, Piewngam Pipat, Characterization and immunomodulatory activity of sulfated galactan from the red seaweed Gracilaria fisheri, International Journal of Biological Macromolecules, 189, 2021. Crossref

  93. Vancheri Carlo, Mastruzzo Claudio, Trovato-Salinaro Elisa, Gili Elisa, Lo Furno Debora, Pistorio Maria P, Caruso Massimo, La Rosa Cristina, Crimi Claudia, Failla Marco, Crimi Nunzio, Interaction between human lung fibroblasts and T-lymphocytes prevents activation of CD4+ cells, Respiratory Research, 6, 1, 2005. Crossref

  94. Gokhale Ameya, Weldeghiorghis Thomas K., Taneja Veena, Satyanarayanajois Seetharama D., Conformationally Constrained Peptides from CD2 To Modulate Protein–Protein Interactions between CD2 and CD58, Journal of Medicinal Chemistry, 54, 15, 2011. Crossref

  95. Arlen Philip M, Mohebtash Mahsa, Madan Ravi A, Gulley James L, Promising novel immunotherapies and combinations for prostate cancer, Future Oncology, 5, 2, 2009. Crossref

  96. Samoilova Elena B., Horton Jennifer L., Chen Youhai, Experimental Autoimmune Encephalomyelitis in Intercellular Adhesion Molecule-1-Deficient Mice, Cellular Immunology, 190, 1, 1998. Crossref

  97. Al-Aghbar Mohammad Ameen, Jainarayanan Ashwin K., Dustin Michael L., Roffler Steve R., The interplay between membrane topology and mechanical forces in regulating T cell receptor activity, Communications Biology, 5, 1, 2022. Crossref

  98. Raghavendra V, Singh V, Shaji A V, Vohra H, Kulkarni S K, Agrewala J N, Melatonin provides signal 3 to unprimed CD4+ T cells but failed to stimulate LPS primed B cells, Clinical and Experimental Immunology, 124, 3, 2001. Crossref

  99. Li Chiang J., Ueda Yutaka, Shi Bin, Borodyansky Laura, Huang Lili, Li You-Zhi, Pardee Arthur B., Tat protein induces self-perpetuating permissivity for productive HIV-1 infection, Proceedings of the National Academy of Sciences, 94, 15, 1997. Crossref

  100. Berndt Uta, Philipsen Lars, Bartsch Sebastian, Wiedenmann Bertram, Baumgart Daniel C., Hämmerle Marcus, Sturm Andreas, Systematic High-Content Proteomic Analysis Reveals Substantial Immunologic Changes in Colorectal Cancer, Cancer Research, 68, 3, 2008. Crossref

  101. Morse Michael A., Clay Timothy M., Hobeika Amy C., Osada Takuya, Khan Shubi, Chui Stephen, Niedzwiecki Donna, Panicali Dennis, Schlom Jeffrey, Lyerly H. Kim, Phase I Study of Immunization with Dendritic Cells Modified with Fowlpox Encoding Carcinoembryonic Antigen and Costimulatory Molecules, Clinical Cancer Research, 11, 8, 2005. Crossref

  102. SHAFIULLA Shaik, DHANESHWAR Suneela, Recent Advancements in Antipsoriatic Therapy: An Update, Fabad Journal of Pharmaceutical Sciences, 2022. Crossref

  103. Consalvo Kristen M., Kirolos Sara A., Sestak Chelsea E., Gomer Richard H., Sex-Based Differences in Human Neutrophil Chemorepulsion, The Journal of Immunology, 209, 2, 2022. Crossref

  104. Toor Amir A., Stiff Patrick J., Nickoloff Brian J., Rodriguez Tulio, Klein Jared L., Gordon Kenneth B., Alefacept in corticosteroid refractory graft versus host disease: Early results indicate promising activity, Journal of Dermatological Treatment, 18, 1, 2007. Crossref

  105. Slavin-Chiorini Dale C, Catalfamo Marta, Kudo-Saito Chie, Hodge James W, Schlom Jeffrey, Sabzevari Helen, Amplification of the lytic potential of effector/memory CD8+ cells by vector-based enhancement of ICAM-1 (CD54) in target cells: implications for intratumoral vaccine therapy, Cancer Gene Therapy, 11, 10, 2004. Crossref

  106. Dahal Achyut, Parajuli Pravin, Singh Sitanshu S., Shrestha Leeza, Sonju Jafrin Jobayer, Shrestha Prajesh, Chatzistamou Ioulia, Jois Seetharama, Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model, Journal of Pharmacological Sciences, 149, 3, 2022. Crossref

  107. Wang Xiaoping, Lewis Dorothy E., CD86 expression correlates with amounts of HIV produced by macrophages in vitro , Journal of Leukocyte Biology, 69, 3, 2001. Crossref

Последний выпуск

Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Gene Analysis Jian Shen, Minzhe Li Exploration of Diagnostic Markers Associated with Inflammation in Chronic Kidney Disease Based on WGCNA and Machine Learning Qianjia Wu, Yang Yang, Chongze Lin Exploring the Mechanism of Zilongjin in Treating Lung Adenocarcinoma Based on Network Pharmacology Combined with Experimental Verification Kang Zhang, Xiaoqun Chen Efficacy and Nuances of Precision Molecular Engineering for Hodgkin’s Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain The Protective Effect and Mechanism of Mild Hypothermia on Lung Injury after Cardiopulmonary Resuscitation in Pigs Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Phillygenin Alleviates Arthritis through the Inhibition of the NLRP3 Inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, Peihong Zhang, Hong Chang Current and Future States of Natural Killer Cell−Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven S. Raman, Anahid Jewett, Jason Chiang Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett Clinical Significance of Serum CTRP3 Level in the Prediction of Cardiac and Intestinal Mucosal Barrier Dysfunction in Patients with Severe Acute Pancreatitis Qiang Shao, Lin Sun

Статьи, принятые к публикации

Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain