Доступ предоставлен для: Guest
Critical Reviews™ in Oncogenesis
Главный редактор: Benjamin Bonavida (open in a new tab)

Выходит 4 номеров в год

ISSN Печать: 0893-9675

ISSN Онлайн: 2162-6448

SJR: 0.395 SNIP: 0.322 CiteScore™:: 2.5 H-Index: 54

Indexed in

Implication of Cyclin D1 in Malignant Lymphoma

Том 7, Выпуск 3-4, 1996, pp. 191-204
DOI: 10.1615/CritRevOncog.v7.i3-4.30
Get accessGet access

Краткое описание

The chromosomal translocation t( 11; 14)(ql 3;q32) is observed in a number of lymphoid malignancies but is specifically associated with a particular subtype of non-Hodgkin's lymphoma called mantle cell lymphoma, where it is observed in up to 70% of cases. This translocation juxtaposes 1GH sequences at 14q32 to a region variously termed BCL1/PRAD1 at 11q13, on the derivative chromosome 11. Detailed molecular analysis identified BCL1 to be a gene coding for the G1 cyclin, cyclin D1, which is an important regulator of the G1/S transition of the cell cycle. Cyclin Dl overexpression is observed in a vast majority of mantle cell lymphoma and lymphoid malignancies with 11ql3 rearrangement, thereby confirming BCL1, now referred to as CCND1, as the gene targeted by these rearrangements. In this review, following a brief discussion of the role of cyclin Dl in cell cycle regulation, we discuss the mechanisms and pathogenetic impact of cyclin D1 activation in lymphoproliferative disorders with 11q13 rearrangement. We also review a number of the diagnostic strategies available for detection of CCND1 rearrrangement/overexpression, with particular emphasis on applications for mantle cell lymphoma.

ЦИТИРОВАНО В
  1. Pommier Yves, Yu Qiang, Kohn Kurt W., NOVEL TARGETS IN THE CELL CYCLE AND CELL CYCLE CHECKPOINTS, in Anticancer Drug Development, 2002. Crossref

  2. Le Baccon Patricia, Leroux Dominique, Dascalescu Christina, Duley Samuel, Marais Danielle, Esmenjaud Eliane, Sotto Jean Jacques, Callanan Mary, Novel evidence of a role for chromosome 1 pericentric heterochromatin in the pathogenesis of B-cell lymphoma and multiple myeloma, Genes, Chromosomes and Cancer, 32, 3, 2001. Crossref

  3. Park S-H, Suh Y-L, Expression of cyclin A and topoisomerase IIα of oligodendrogliomas is correlated with tumour grade, MIB-1 labelling index and survival, Histopathology, 42, 4, 2003. Crossref

  4. Sathanoori Malini, Shekhter-Levin Sofia, Marks Stanley M., Swerdlow Steven H., Derivative (14)t(11;14)(q13;q32)t(11;14)(p11.2;p11.2): a novel unbalanced variant of the t(11;14)(q13;q32) translocation in mantle cell lymphoma, Cancer Genetics and Cytogenetics, 172, 2, 2007. Crossref

  5. Ahlborn Gene J., Nelson Gail M., Ward William O., Knapp Geremy, Allen James W., Ouyang Ming, Roop Barbara C., Chen Yan, O'Brien Thomas, Kitchin Kirk T., Delker Don A., Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite, Toxicology and Applied Pharmacology, 227, 3, 2008. Crossref

  6. Sahasrabuddhe Anagh A., Elenitoba-Johnson Kojo S.J., The role of aberrant proteolysis in lymphomagenesis, Current Opinion in Hematology, 22, 4, 2015. Crossref

  7. Drexler Hans G, MacLeod Roderick A.F, Malignant hematopoietic cell lines: in vitro models for the study of mantle cell lymphoma, Leukemia Research, 26, 9, 2002. Crossref

  8. Janssen Johannes W.G., Cuny Marguerite, Orsetti Béatrice, Rodriguez Carmen, Vallés Hélène, Bartram Claus R., Schuuring Ed, Theillet Charles, MYEOV: A candidate gene for DNA amplification events occurring centromeric toCCND1in breast cancer, International Journal of Cancer, 102, 6, 2002. Crossref

  9. Moody Brent R., Bartlett Nancy L., George David W., Price Caroline R., Breer Wayne A., Rothschild Yadira, Kraus Madeleine D., Cyclin D1 as an Aid in the Diagnosis of Mantle Cell Lymphoma in Skin Biopsies: A Case Report, The American Journal of Dermatopathology, 23, 5, 2001. Crossref

  10. Huang Hu, Hu Yi-de, Li Na, Zhu Yong, Inhibition of Tumor Growth and Metastasis by Non–Small Cell Lung Cancer Cells Transfected With Cyclin D1–Targeted siRNA, Oligonucleotides, 19, 2, 2009. Crossref

  11. Anderson Christopher B., Lipsky Michael, Nandula Subhadra V., Freeman Christopher E., Matthews Thomas, Walsh Caitlin E., Li Gen, Szabolcs Matthias, Mansukhani Mahesh M., McKiernan James M., Murty Vundavalli V., Cytogenetic analysis of 130 renal oncocytomas identify three distinct and mutually exclusive diagnostic classes of chromosome aberrations, Genes, Chromosomes and Cancer, 59, 1, 2020. Crossref

  12. Fu Maofu, Wang Chenguang, Li Zhiping, Sakamaki Toshiyuki, Pestell Richard G., Minireview: Cyclin D1: Normal and Abnormal Functions, Endocrinology, 145, 12, 2004. Crossref

  13. Gustavsson Elin, Sernbo Sandra, Andersson Elin, Brennan Donal J., Dictor Michael, Jerkeman Mats, Borrebaeck Carl A. K., Ek Sara, SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies, Molecular Cancer, 9, 1, 2010. Crossref

  14. Inoue Jun, Otsuki Takemi, Hirasawa Akira, Imoto Issei, Matsuo Yoshinobu, Shimizu Shiroh, Taniwaki Masafumi, Inazawa Johji, Overexpression of PDZK1 within the 1q12-q22 Amplicon Is Likely To Be Associated with Drug-Resistance Phenotype in Multiple Myeloma, The American Journal of Pathology, 165, 1, 2004. Crossref

  15. Goy Andre, Mantle cell lymphoma, in Management of Hematologic Malignancies, 2010. Crossref

  16. La Ping, Fernando Amal P., Wang Zhi, Salahudeen Ameen, Yang Guang, Lin Qing, Wright Clyde J., Dennery Phyllis A., Zinc Protoporphyrin Regulates Cyclin D1 Expression Independent of Heme Oxygenase Inhibition, Journal of Biological Chemistry, 284, 52, 2009. Crossref

  17. Callanan Mary B., Le Baccon Patricia, Mossuz Pascal, Duley Samuel, Bastard Christian, Hamoudi Rifat, Dyer Martin J., Klobeck Gustav, Rimokh Ruth, Sotto Jean Jacques, Leroux Dominique, The IgG Fc receptor, FcγRIIB, is a target for deregulation by chromosomal translocation in malignant lymphoma, Proceedings of the National Academy of Sciences, 97, 1, 2000. Crossref

Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain