Доступ предоставлен для: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Выходит 6 номеров в год

ISSN Печать: 1045-4403

ISSN Онлайн: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Target Genes and Cellular Regulators of the Мус Transcription Complex

Том 8, Выпуск 3-4, 1998, pp. 277-296
DOI: 10.1615/CritRevEukarGeneExpr.v8.i3-4.30
Get accessGet access

Краткое описание

Precisely how the Myc proteins promote cellular growth and transformation remains an enigma. Structural and functional studies unequivocally demonstrate that Myc proteins have the potential to function as regulators of gene transcription in vivo. Therefore, the current view is that Myc-induced cellular growth is orchestrated by products of the genes regulated by Myc and that efforts to curtail Myc function are best directed toward the accessory proteins that interact with Myc to modulate its function as a transcription factor. This review is focused on recent work designed to identify the genetic targets of Myc activity in cells and to characterize Myc-interacting proteins. These studies have provided an intriguing set of molecular tools that can be exploited to generate new information on the role of Myc in cell growth and oncogenic transformation.

Ключевые слова: Myc, transcription, transformation, oncogenes.
ЦИТИРОВАНО В
  1. Daumer Kathleen M., Taparowsky Elizabeth J., Hall David J., Steinbeck Marla J., Transcription From the Tartrate-resistant Acid Phosphatase Promoter Is Negatively Regulated by the Myc Oncoprotein, Journal of Bone and Mineral Research, 17, 9, 2002. Crossref

  2. Oster Sara K., Ho Cynthia S.W., Soucie Erinn L., Penn Linda Z., , 84, 2002. Crossref

  3. Sosinsky Alona, Glusman Gustavo, Lancet Doron, The Genomic Structure of Human Olfactory Receptor Genes, Genomics, 70, 1, 2000. Crossref

  4. Jacobs Heinz, TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function, Seminars in Immunology, 12, 5, 2000. Crossref

  5. Vanden Heuvel J.P., Receptor-Mediated Carcinogenesis, in Comprehensive Toxicology, 2010. Crossref

  6. Wang Xueyan, Peters Mette A., Utama Fransiscus E., Wang Yuzhen, Taparowsky Elizabeth J., The Adrenomedullin Gene Is a Target for Negative Regulation by the Myc Transcription Complex, Molecular Endocrinology, 13, 2, 1999. Crossref

  7. Burton Robert A., Mattila Sampo, Taparowsky Elizabeth J., Post Carol Beth, B-Myc:  N-Terminal Recognition of Myc Binding Proteins, Biochemistry, 45, 32, 2006. Crossref

  8. Luo Qi, Li Jun, Cenkci Belgin, Kretzner Leo, Autorepression of c-myc requires both initiator and E2F-binding site elements and cooperation with the p107 gene product, Oncogene, 23, 5, 2004. Crossref

  9. Meroni Germana, Cairo Stefano, Merla Giuseppe, Messali Silvia, Brent Roger, Ballabio Andrea, Reymond Alexandre, Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?, Oncogene, 19, 29, 2000. Crossref

  10. McMahon Steven B., Wood Marcelo A., Cole Michael D., The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc, Molecular and Cellular Biology, 20, 2, 2000. Crossref

  11. Dudley JP, Mertz JA, Rajan L, Lozano M, Broussard DR, What retroviruses teach us about the involvement of c-Myc in leukemias and lymphomas, Leukemia, 16, 6, 2002. Crossref

Статьи, принятые к публикации

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain