Выходит 12 номеров в год
ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Anti-Inflammatory and Wound-Healing Potential of Golden Chanterelle Mushroom, Cantharellus cibarius (Agaricomycetes)
Get access
Краткое описание
The golden chanterelle mushroom, Cantharellus cibarius, is an edible mushroom with medicinal value. Given that this species has good radical scavenging activity and strong antioxidant potential and bactericidal effects, this study was designed to investigate the anti-inflammatory and wound-healing activity of C. cibarius extract in rats. For this experimental study, circular excision and linear incision wound models were used in 4 groups of male Wistar rats: nontreated, vehicle-treated, treated with C. cibarius extract ointment (2% w/w), and treated with the reference drug (Madecassol). All the animals were treated topically once a day. The circular and linear wounds were treated for 9 and 17 days, respectively. At the end of the study, samples from healing wounds were taken for histopathological assessment to determine the in vivo anti-inflammatory activity and investigate immunohistochemistry by cyclooxygenase-2 (COX-2). Significant wound-healing activity in each wound model was observed in the C. cibarius extract–treated and Madecassol-treated groups compared with the nontreated and vehicle-treated groups (P < 0.05). Histological assessment showed complete repair of the epidermal layer, increased collagen production, and a remarkable degree of neovascularization and epithelization in the extract group, which were significantly different from those in the other groups (P < 0.05). In addition, a significantly lower rate of COX-2 expression was detected in the extract group than in the nontreated and vehicle-treated groups (P < 0.0001). Therefore, the experimental data reveal that C. cibarius extract showed significant wound-healing and anti-inflammatory effects, which could be the scientific rationale for the medicinal use of the golden chanterelle mushroom in treating wounds.
-
Vlasenko Vyacheslav, Turmunkh Dejidmaa, Ochirbat Enkhtuya, Budsuren Dondov, Nyamsuren Kherlenchimeg, Samiya Javkhlan, Ganbaatar Burenbaatar, Vlasenko Anastasia, Lashinsky N.N., Makunina N.I., Medicinal potential of extracts from the chanterelle mushroom, Cantharellus cibarius (Review) and prospects for studying its strains from differs plant communities of ultracontinental regions of the Asia, BIO Web of Conferences, 16, 2019. Crossref
-
Papazov Penko, Denev Panteley, DETERMINATION PHOSPHOLIPIDS OF WILD EDIBLE MUSHROOMS (SUILLUS LUTEUS), Applied Researches in Technics, Technologies and Education, 6, 4, 2018. Crossref
-
Lemieszek Marta K., Nunes Fernando M., Rzeski Wojciech, Branched mannans from the mushroom Cantharellus cibarius enhance the anticancer activity of natural killer cells against human cancers of lung and colon, Food & Function, 10, 9, 2019. Crossref
-
Nasiry Davood, Khalatbary Ali Reza, Ahmadvand Hassan, Talebpour Amiri Fereshteh Beigom, Effects of Juglans regia L. leaf extract supplementation on testicular functions in diabetic rats, Biotechnic & Histochemistry, 96, 1, 2021. Crossref
-
YILDIZ Filiz, Mengen’de Yetişen Bazı Yabani Mantar Türlerinin Doğal Boya Kaynağı Olarak Değerlendirilmesi, European Journal of Science and Technology, 2020. Crossref
-
Nasiry Davood, Khalatbary Ali Reza, Abdollahifar Mohammad-Amin, Amini Abdollah, Bayat Mohammad, Noori Afshin, Piryaei Abbas, Engraftment of bioengineered three-dimensional scaffold from human amniotic membrane-derived extracellular matrix accelerates ischemic diabetic wound healing, Archives of Dermatological Research, 313, 7, 2021. Crossref
-
Nilforoushzadeh Mohammad Ali, Raoofi Amir, Afzali Hamideh, Gholami Omid, Zare Sona, Nasiry Davood, Khodaverdi Darian Ebrahim, Rustamzadeh Auob, Alavi Shiva, Ahmadi Rahim, Alimohammadi Alimohammad, Razzaghi Zahra, Safaie Naraghi Zahra, Mahmoudbeyk Mona, Amirkhani Mohammad Amir, Mousavi Khaneghah Amin, Promotion of cutaneous diabetic wound healing by subcutaneous administration of Wharton's jelly mesenchymal stem cells derived from umbilical cord, Archives of Dermatological Research, 2022. Crossref
-
Ahmed Elkhateeb Waill, Mosbah Daba Ghoson, Medicinal mushroom: What should we know?, International Journal of Pharmaceutical Chemistry and Analysis, 9, 1, 2022. Crossref
-
Marathe Sandesh J., Hamzi Wahiba, Bashein Abdulla M., Deska Jan, Seppänen-Laakso Tuulikki, Singhal Rekha S., Shamekh Salem, Anti-Angiogenic Effect of Cantharellus cibarius Extracts, its Correlation with Lipoxygenase Inhibition, and Role of the Bioactives Therein, Nutrition and Cancer, 74, 2, 2022. Crossref
-
Huang Lei, Wang Mengting, Ebrahimzadeh Mohammad Ali, Jafari Aref, Jiang Kejiao, Stereological and molecular studies on the effects of Ferula persica extract on wound healing in rats , Veterinary Medicine and Science, 8, 1, 2022. Crossref
-
Otaghvar Hamidreza Alizadeh, Rezapour-Nasrabad Rafat, Ebrahimzadeh Mohammad Ali, Yaghoubi Mehran, Khalatbary Ali Reza, Nasiry Davood, Raoofi Amir, Rostamzadeh Auob, The effects of Feijoa sellowiana fruit extract on wound healing in rats: a stereological and molecular study, Journal of Wound Care, 31, Sup8, 2022. Crossref
-
Davoodi Sima, Ebrahimpour‐Malekshah Roohollah, Ayna Ömer, Akbari Mitra, Raoofi Amir, Mokhtari Hossein, Izanlu Mostafa, Modanloo Faezeh, Nasiry Davood, Decellularized human amniotic membrane engraftment in combination with adipose‐derived stem cells transplantation, synergistically improved diabetic wound healing, Journal of Cosmetic Dermatology, 2022. Crossref
-
Nasiry Davood, Khalatbary Ali Reza, Ghaemi Alireza, Ebrahimzadeh Mohammad Ali, Hosseinzadeh Mohammad Hossein, Topical administration of Juglans regia L. leaf extract accelerates diabetic wound healing, BMC Complementary Medicine and Therapies, 22, 1, 2022. Crossref