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International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

Выходит 12 номеров в год

ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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In Vitro Antitumor Activity and Structure Characterization of Ethanol Extracts from Wild and Cultivated Chaga Medicinal Mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae)

Том 13, Выпуск 2, 2011, pp. 121-130
DOI: 10.1615/IntJMedMushr.v13.i2.40
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Краткое описание

Inonotus obliquus (Pers.:Fr.) Pilat has been traditionally used as a folk remedy for treatment of cancers, cardiovascular disease and diabetes in Russia, Poland, and most of the Baltic countries, but natural reserves of this fungus have nearly been exhausted. This study was designed to investigate the artificial cultivation of I. obliquus and the antitumor activity of its tissues. The ethanol extract of cultivated sclerotium had the highest cell growth inhibitory rate (74.6%) as determined by an 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. 78% of the bags produced sclerotia and only 6.17 g/bag of sclerotium was obtained. Extracts of the cultivated fruiting body showed 44.2% inhibitory activity against tumor cells. However, the yield was as high as 18.24 g/bag, and 98% of the bags produced fruiting body. The results of gas chromatography-mass spectroscopy (GC-MS) showed that similar compounds were extracted from the wild and cultivated samples. The principal compounds observed were lanosterol, inotodiol, and ergosterol. Their percentages of the mass fraction were 86.1, 59.9, and 71.8% of the total, for the wild sclerotium, cultivated sclerotium, and cultivated fruiting body, respectively. Ergosterol was found to be much higher (27.32%) in cultivated fruiting body. We conclude that cultivated fruiting body of I. obliquus obtained by inoculation of the substrate with spawn mycelium of the fifth generation could serve as an ideal substitute for the wild I. obliquus.

ЦИТИРОВАНО В
  1. Song Fu-Qiang, Liu Ying, Kong Xiang-Shi, Chang Wei, Song Ge, Progress on Understanding the Anticancer Mechanisms of Medicinal Mushroom: Inonotus Obliquus, Asian Pacific Journal of Cancer Prevention, 14, 3, 2013. Crossref

  2. Lee Hyun Sook, Kim Eun Ji, Kim Sun Hyo, Ethanol extract ofInnotus obliquus(Chaga mushroom) induces G1cell cycle arrest in HT-29 human colon cancer cells, Nutrition Research and Practice, 9, 2, 2015. Crossref

  3. Nikitina S.A., Khabibrakhmanova V.R., Sysoeva M.A., Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga), Biomeditsinskaya Khimiya, 62, 4, 2016. Crossref

  4. Nikitina S. A., Habibrakhmanova V. R., Sysoeva M. A., Chemical composition and biological activity of triterpenes and steroids of chaga mushroom, Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 10, 1, 2016. Crossref

  5. Patel Seema, Goyal Arun, Recent developments in mushrooms as anti-cancer therapeutics: a review, 3 Biotech, 2, 1, 2012. Crossref

  6. Zhang Jiao-Jiao, Li Ya, Zhou Tong, Xu Dong-Ping, Zhang Pei, Li Sha, Li Hua-Bin, Bioactivities and Health Benefits of Mushrooms Mainly from China, Molecules, 21, 7, 2016. Crossref

  7. Lau Beng Fye, Abdullah Noorlidah, Sclerotium-Forming Mushrooms as an Emerging Source of Medicinals, in Mushroom Biotechnology, 2016. Crossref

  8. Deepalakshmi Krishnamoorthy, Mirunalini Sankaran, Antiproliferative and apoptotic effect ofPleurotus ostreatuson human mammary carcinoma cell line (michigan cancer foundation-7), Cancer Translational Medicine, 2, 4, 2016. Crossref

  9. Staniszewska Justyna, Szymański Marcin, Ignatowicz Ewa, Antitumor and immunomodulatory activity of Inonotus obliquus , Herba Polonica, 63, 2, 2017. Crossref

  10. Rezaeian Sharareh, Pourianfar Hamid R., A comparative study on cytotoxicity and antiproliferative activities of crude extracts and fractions from Iranian wild-growing and cultivated Agaricus spp., Journal of Food Measurement and Characterization, 12, 4, 2018. Crossref

  11. Fradj , Gonçalves dos Santos , de Montigny , Awwad , Boumghar , Germain , Desgagné-Penix , RNA-Seq de Novo Assembly and Differential Transcriptome Analysis of Chaga (Inonotus obliquus) Cultured with Different Betulin Sources and the Regulation of Genes Involved in Terpenoid Biosynthesis, International Journal of Molecular Sciences, 20, 18, 2019. Crossref

  12. Patel Seema, Chaga (Inonotus Obliquus) Mushroom: Nutraceutical Assesement Based on Latest Findings, in Emerging Bioresources with Nutraceutical and Pharmaceutical Prospects, 2015. Crossref

  13. Mohammadnejad Safoora, Pourianfar Hamid R., Drakhshan Ahmad, Jabaleh Isa, Rezayi Majid, Potent antiproliferative and pro-apoptotic effects of a soluble protein fraction from culinary-medicinal mushroom Lentinus tigrinus on cancer cells, Journal of Food Measurement and Characterization, 13, 4, 2019. Crossref

  14. Eid Jehane Ibrahim, Das Biswadeep, Molecular insights and cell cycle assessment upon exposure to Chaga (Inonotus obliquus) mushroom polysaccharides in zebrafish (Danio rerio), Scientific Reports, 10, 1, 2020. Crossref

  15. Sun Xueyan, Liu Dongmei, Wang Yuanyuan, Ma Aimin, Biogenesis of macrofungal sclerotia: influencing factors and molecular mechanisms, Applied Microbiology and Biotechnology, 104, 10, 2020. Crossref

  16. Upska Karina, Klavins Linards, Radenkovs Vitalijs, Nikolajeva Vizma, Faven Leena, Isosaari Eveliina, Lauberts Maris, Busa Lauma, Viksna Arturs, Klavins Maris, Extraction possibilities of lipid fraction and authentication assessment of chaga (Inonotus obliquus), Biomass Conversion and Biorefinery, 2022. Crossref

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