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International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

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ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

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Extract of Caterpillar Medicinal Mushroom, Cordyceps milifaris (Ascomycetes), Mycelia Attenuates Doxorubicin-Induced Cardiotoxicity and Upregulates Mitochondrial Electron Transport Chain Activity in Rats

Том 23, Выпуск 1, 2021, pp. 17-26
DOI: 10.1615/IntJMedMushrooms.2020037199
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Краткое описание

The anthracycline antibiotic doxorubicin (DOX) is extensively used in cancer chemotherapy. Cumulative dose-dependent cardiotoxicity may develop even several years after DOX treatment. This study aimed to evaluate the protective effect of aqueous ethanol extract of Cordyceps militaris mycelia (CM) against DOX-induced cardiotoxicity in rats. DOX was administered intraperitoneally at a cumulative dose of 18 mg/kg of body weight (BW). The protective effect was evaluated using CM at doses of 150 and 300 mg/kg BW administered orally. DL-alpha-lipoic acid (100 mg/ kg BW) was used as the reference control. Both serum creatine kinase and lactate dehydrogenase activities were elevated significantly (P < 0.01) in the group treated with DOX alone compared to the control or CM + DOX-treated groups. DOX administration significantly decreased (P < 0.01) adenosine triphosphate levels and activity of complexes I, III, and IV and Krebs cycle dehydrogenases. CM treatment (300 mg/kg BW) upregulated decreased mitochondrial enzyme activity consequent to DOX administration. Histopathological observations revealed the amelioration of cardiac myocyte necrosis and hypertrophy, which supported the protective effect of CM.

ЛИТЕРАТУРА
  1. Weiss RB. The anthracyclines: Will we ever find a better doxorubicin? Semin Oncol. 1992;19:670-86.

  2. Zhang S, Liu X, Bawa-Khalfe T, Lu LS, Lyu YL, Liu LF, Yeh ET. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat Med. 2012;18:1639-42.

  3. Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol. 1997;57:727-41.

  4. Ghigo A, Li M, Hirsch E. New signal transduction paradigms in anthracycline-induced cardiotoxicity. Biochim Biophys Acta. 2016;1863:1916-25.

  5. Garner AP, Paine MJ, Rodriguez-Crespo I, Chinje EC, Ortiz De Montellano P, Stratford IJ, Tew DG, Wolf CR. Nitric oxide synthases catalyze the activation of redox cycling and bioreductive anticancer agents. Cancer Res. 1999;59:1929-34.

  6. Songbo M, Lang H, Xinyong C, Bin X, Ping Z, Liang S. Oxidative stress injury in doxorubicin-induced cardiotoxicity. Toxicol Lett. 2019;307:41-8.

  7. Swain SM, Whaley FS, Ewer MS. Congestive heart failure in patients treated with doxorubicin: A retrospective analysis of three trials. Cancer. 2003;97:2869-79.

  8. Chatterjee K, Zhang J, Honbo N, Karliner JS. Doxorubicin cardiomyopathy. Cardiology. 2010;115:155-62.

  9. Jung SJ, Jung ES, Choi EK, Sin HS, Ha KC, Chae SW. Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): A randomized and double-blind clinical trial. BMC Complement Altern Med. 2019;19:77.

  10. Qiao J, Shuai Y, Zeng X, Xu D, Rao S, Zeng H, Li F. Comparison of chemical compositions, bioactive ingredients, and in vitro antitumor activity of four products of Cordyceps (Ascomycetes) strains from China. Int J Med Mushrooms. 2019;21:331-42.

  11. Nurmamat E, Xiao H, Zhang Y, Jiao Z. Effects of different temperatures on the chemical structure and antitumor activities of polysaccharides from Cordyceps militaris. Polymers. 2018;10:430.

  12. Dong CH, Yang T, Lian T. A comparative study of the antimicrobial, antioxidant, and cytotoxic activities of methanol extracts from fruit bodies and fermented mycelia of caterpillar medicinal mushroom Cordyceps militaris (Ascomycetes). Int J Med Mushrooms. 2014;16:485-95.

  13. Ong BY, Aziz Z. Efficacy of Cordyceps sinensis as an adjunctive treatment in kidney transplant patients: A systematic-review and meta-analysis. Complement Ther Med. 2017;30:84-92.

  14. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients. Cochrane Database Syst Rev. 2015;12;CD009698.

  15. Ajith TA, Sudheesh NP, Roshny D, Abishek G, Janardhanan KK. Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats. Exp Gerontol. 2009;44:219-23.

  16. Fatania H, al-Nassar KE, Sidhan V. Purification and partial characterization NADP+-linked isocitrate dehydrogenase from rat liver cytosol. FEBS Lett. 1993;320:57-60.

  17. Reed LJ, Mukherjee BB. a-ketoglutarate dehydrogenase complex from Escherichia coli. Methods Enzymol. 1969;13:55-61.

  18. Nulton-PerssonAC, Szweda LI. Modulation ofmitochondrial function by hydrogen peroxide. J Biol Chem. 2001;276:23357-61.

  19. Mehler AH, Kornberg A, Grisolia S, Ochia S. The enzymatic mechanisms of oxidation-reductions between malate or isocitrate and pyruvate. J Biol Chem. 1948;174:961-71.

  20. Janssen AJ, Trijbels FJ, Sengers RC, Smeitink JA, van den Heuvel LP, Wintjes LT, Stoltenborg-Hogenkamp BJ, Rodenburg RJ. Spectrophotometric assay for complex I of the respiratory chain in tissue samples and cultured fibroblasts. Clin Chem. 2007;53:729-34.

  21. Krahenbuhl S, Chang M, Brass EP, Hoppel CL. Decreased activities of ubiquinol:ferricytochrome c oxidoreductase (complex III) and ferricytochrome c:oxygen oxidoreductase (complex IV) in liver mitochondria from rats with hydroxocobalamin[c lactam]-induced methylmalonic aciduria. J Biol Chem. 1991;266:20998-30003.

  22. Capaldi RA, Marusich MF, Taanman JW. Mammalian cytochrome-c oxidase: Characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells. Methods Enzymol. 1995;260:117-32.

  23. Lowry HD, Rosenberg NJ, Farr AL, Randa RJ. Protein measurement with Folin phenol reagent. J Biol Chem. 1951;193:265-75.

  24. Zilinyi R, Czompa A, Czegledi A, Gajtko A, Pituk D, Lekli I, Tosaki A. The cardioprotective effect of metformin in doxorubicin-induced cardiotoxicity: The role of autophagy. Molecules. 2018;23:1184.

  25. Veena, RK, Ajith TA, Janardhanan KK. Lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Agaricomycetes), prevents doxorubicin-induced cardiotoxicity in rat. Int J Med Mushrooms. 2018;20:761-74.

  26. Sudheesh NP, Ajith TA, Janardhanan KK. Ganoderma lucidum ameliorate mitochondrial damage in isoproterenol-induced myocardial infarction in rats by enhancing the activities of TCA cycle enzymes and respiratory chain complexes. Int J Cardiol. 2013;165:117-25.

  27. Ajith TA, Nima N, Veena RK, Janardhanan KK, Antonawich F. Effect of palladium a-lipoic acid complex on energy in the brain mitochondria of aged rats. Altern Ther Health Med. 2014;20:27-35.

  28. Minotti G, Recalcati S, Menna P, Salvatorelli E, Corna G, Cairo G. Doxorubicin cardiotoxicity and the control of iron metabolism: Quinone-dependent and independent mechanisms. Methods Enzymol. 2004;378:340-61.

  29. Hu X, Li B, Li L, Li B, Luo J, Shen B. Asiatic acid protects against doxorubicin-induced cardiotoxicity in mice. Oxid Med Cell Longev. 2020;2020:5347204.

  30. Clementi ME, Giardina B, Di Stasio E, Mordente A, Misiti F. Doxorubicin-derived metabolites induce release of cytochrome C and inhibition of respiration on cardiac isolated mitochondria. Anticancer Res. 2003;23:2445-50.

  31. Yeh ET, Chang HM. Oncocardiology-past, present, and future: A review. JAMA Cardiol. 2016;1:1066-72.

  32. Tscheschner H, Meinhardt E, Schlegel P, Jungmann A, Lehmann LH, Muller OJ, Most P, Katus HA, Raake PW. CaM-KII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression. PLoS One. 2019;14:e0215992.

  33. Ghibu S, Delemasure S, Richard C, Guilland JC, Martin L, Gambert S, Rochette L, Vergely C. General oxidative stress during doxorubicin-induced cardiotoxicity in rats: Absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid. Biochimie. 2012;94:932-9.

  34. Chang HM, Moudgil R, Scarabelli T, Okwuosa TM, Yeh ETH. Cardiovascular complications of cancer therapy: Best practices in diagnosis, prevention, and management: Part 1. J Am Coll Cardiol. 2017;70:2536-51.

  35. Vandecruys E, Mondelaers V, De Wolf D, Benoit Y, Suys B. Late cardiotoxicity after low dose of anthracycline therapy for acute lymphoblastic leukemia in childhood. J Cancer Surviv. 2012;6:95-101.

  36. Nysom K, Holm K, Lipsitz SR, Mone SM, Colan SD, Orav EJ, Sallan SE, Olsen JH, Hertz H, Jacobsen JR, Lipshultz SE. Relationship between cumulative anthracycline dose and late cardiotoxicity in childhood acute lymphoblastic leukemia. J Clin Oncol. 1998;16:545-50.

  37. Pritsos CA, Ma J. Basal and drug-induced antioxidant enzyme activities correlate with age-dependent doxorubicin oxidative toxicity. Chem Biol Interact. 2000;127:1-11.

  38. Suh JH, Heath SH, Hagen TM. Two populations of mitochondria in the aging rat heart display heterologous levels of oxidative stress. Free Radic Biol. Med. 2003;35:1064-72.

  39. Lesnefsky EJ, Hoppel CL. Oxidative phosphorylation and aging. Ageing Res Rev. 2006;5:402-33.

  40. Wen J, Wang J, Li P, Wang R, Wang J, Zhou X, Zhang L, Li H, Wei S, Cai H, Zhao Y. Protective effects of dienamine combined with [6]-gingerol against doxorubicin-induced mitochondrial dysfunction and toxicity in H9c2 cells and potential mechanisms. Biomed Pharmacother. 2019;115:108881.

  41. Chen X, Peng X, Luo Y, You J, Yin D, Xu Q, He H, He M. Quercetin protects cardiomyocytes against doxorubicin-induced toxicity by suppressing oxidative stress and improving mitochondrial function via 14-3-3y. Toxicol Mech Methods. 2019;29:344-54.

  42. Tuli HS, Sardul SS, Sharma AK. Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin. 3 Biotech. 2014;4:1-12.

  43. Veena RK, Carmel EJ, Ramya H, Ajith TA, Wasser SP, Janardhanan KK. Caterpillar medicinal mushroom, Cordyceps militaris (Ascomycetes), mycelia attenuates doxorubicin-induced oxidative stress and upregulates Krebs cycle dehydrogenases activity and ATP level in rat brain. Int J Med Mushrooms. 2020;22:593-604.

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