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ISSN Печать: 0896-2960
ISSN Онлайн: 2162-6553
Indexed in
Treating Chronic Cognitive Impairment After Traumatic Brain Injury: A Review of Post-traumatic Neurotransmitter-Based Interventions
Краткое описание
Chronic cognitive impairment is a frequent and enduring aspect of traumatic brain injury in both humans and animals. Animal models of traumatically induced cognitive impairment provide the groundwork for future clinical studies aimed at treating chronic cognitive dysfunction after head injury. This article will review the results of posttraumatic neurotransmitter-based interventions aimed at improving cognitive recovery in animal models of traumatic brain injury. The scope of this review is limited to experiments designed to treat the chronic stages of head injury, and the interventions tested must have been initiated after injury and continued for a period of days. Where applicable, results from clinical studies are considered. A brief review of current techniques used in experimental traumatic brain injury are presented.