Library Subscription: Guest
Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Gain Access(open in a new tab)
More
Purchase $35.00(open in a new tab) Check subscription Download MARC record(open in a new tab) Get Permissions(open in a new tab)

Antigen Delivery to Plasmacytoid Dendritic Cells -Induction of Tolerance and Immunity

Volume 32, Issue 6, 2012, pp. 489-501
DOI: 10.1615/CritRevImmunol.v32.i6.20
Submitted: Jul 23 2012 Accepted: Dec 04 2012 Published online: Jan 28 2013
Get accessGet access
Jakob Loschko
Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
Anne Krug (Corresponding author anne.krug@med.lmu.de)
Institute for Immunology, Ludwig-Maximilians-Universität München (LMU)

ABSTRACT

Dendritic cells are professional antigen presenting cells linking the innate and the adaptive immune system. Antibody mediated antigen delivery to functionally distinct DC subpopulations is a promising approach to induce or inhibit antigen specific immune responses in vivo and is useful for designing therapeutic vaccination strategies. This review focuses on the state of the art of this technique and describes recent findings of antigen targeting to the subpopulation of plasmacytoid dendritic cells and the possibilities to induce immunity or attenuate autoimmunity by delivering antigens specifically to this cell type.

KEY WORDS: Plasmacytoid dendritic cells, antigen targeting, tolerance, immunity
CITED BY

  1. Chappell Craig P., Giltiay Natalia V., Dresch Christiane, Clark Edward A., Controlling immune responses by targeting antigens to dendritic cell subsets and B cells, International Immunology, 26, 1, 2014. Crossref

  2. Dillon Patrick M., Slingluff Craig L., Peptide Vaccine: Overview, in Cancer Therapeutic Targets, 2017. Crossref

  3. Chappell Craig P., Giltiay Natalia V., Draves Kevin E., Chen ChangHung, Hayden-Ledbetter Martha S., Shlomchik Mark J., Kaplan Daniel H., Clark Edward A., Targeting Antigens through Blood Dendritic Cell Antigen 2 on Plasmacytoid Dendritic Cells Promotes Immunologic Tolerance, The Journal of Immunology, 192, 12, 2014. Crossref

  4. Dillon Patrick M., Slingluff Craig L., Peptide Vaccine: Overview, in Cancer Therapeutic Targets, 2015. Crossref

  5. Biessen Erik A.L., Christ Anette, Plasmacytoid Dendritic Cells in Atherosclerosis, Circulation, 130, 16, 2014. Crossref

699 Article views 99 Article downloads Metrics
699 VIEWS 99 DOWNLOADS 5 Crossref CITATIONS Google
Scholar CITATIONS

Articles with similar content:

NKT-Licensed In Vivo Dendritic Cell−Based Immunotherapy as Cellular Immunodrugs for Cancer Treatment Critical Reviews™ in Oncogenesis, Vol.29, 2024, issue 1
Kanako Shimizu, Shin-ichiro Fujii
Therapeutic Dendritic Cell−Based Cancer Vaccines: The State of the Art Critical Reviews™ in Immunology, Vol.33, 2013, issue 6
Marius M. Strioga, Valerijus Ostapenko, Daniel J. Powell Jr., Neringa T. Dobrovolskiene, Virgil E. J. C. Schijns, Thomas Felzmann, Jaroslav Michalek, Miroslava Matuskova
CD28-CD80/86 and CD40-CD40L Interactions Promote Thymic Tolerance by Regulating Medullary Epithelial Cell and Thymocyte Development Critical Reviews™ in Immunology, Vol.35, 2015, issue 1
Xuguang Tai , Richard J. Hodes, Joy A. Williams
CD1d-Mediated Antigen Presentation to Natural Killer T (NKT) Cells Critical Reviews™ in Immunology, Vol.23, 2003, issue 5-6
Tonya J. Roberts, Venkataraman Sriram, Yinling Lin, Sungyoo Cho, Randy R. Brutkiewicz, Yu Kyeong Hwang
In Vitro Immunization and Expansion of Antigen-Specific Cytotoxic T Lymphocytes for Adoptive Immunotherapy Using Peptide-Pulsed Dendritic Cells Critical Reviews™ in Immunology, Vol.18, 1998, issue 1-2
Alessandro Sette, Van Tsai, Esteban Celis, Ichiro Kawashima, Elissa Keogh, Kieran Daly

Latest Issue

The Value of Systemic Immune-Inflammation Index and T Cell Subsets in the Severity and Prognosis of Sepsis Hao Zhou MiRNA let-7d-5p Alleviates Inflammatory Responses by Targeting Map3k1 and Inactivating ERK/p38 MAPK Signaling in Microglia Fan Fang, Cheng Chen Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang Effect of the p-Estrogen Receptor at Serine on Its Function and Breast Growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang KIAA1429 Induces m6A Modification of LINC01106 to Enhance the Malignancy of Lung Adenocarcinoma Cells via the JAK/STAT3 Pathway Di Xu, Ziming Wang, Fajiu Li Different Doses of Dexmedetomidine Reduce Postoperative Sleep Disturbance Incidence in Patients under General Anesthesia by Elevating Serum Neurotransmitter Levels Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of a Novel Five-Gene Prognostic Model for Laryngeal Cancer Associated with Mitophagy Using Integrated Bioinformatics Analysis and Experimental Verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Exploring the Mechanism of Isoforskolin against Asthma Based on Network Pharmacology and Experimental Verification Yan Fang, Shibo Sun, Chuang Xiao, Min Li, Yuanyuan Zheng, Anju Zu, Zhuang Luo

Forthcoming Articles

The SLE Conundrum: A Comprehensive Analysis of Pathogenesis, Re-cent Developments, and the Future of Therapeutic Interventions Uddeshya Sharma The effect of supplementation of vitamin D on hyperlipidemia and bone mass in the pediatric with obesity Feifan Wang, Lingshan Bei, Xiaoyan Zhang, Yangxi Fu Identification of key chondrocyte apoptosis-related genes in osteoarthritis based on weighted gene co-expression network analysis and experimental verification Wei Wang, Junyi Hong, Tianyi Cao, Fusheng Ye, Junwei Gao, Shumei Qin Anoikis and Mitophagy-Related Gene Signature for Predicting the Survival and Tumor Cell Progression in Colon Cancer Jian Shen, Minzhe Li Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections Prices and Subscription Policies Begell House Contact Us Language English 中文 Русский Português German French Spain